In the healthcare field today, perhaps no area holds as much promise and as many perils as weight control. Researchers see the same statistics that the rest of us do. They see the upcoming wave of obesity and diabetes diagnoses. They see the myriad complications that spring up from these conditions. And they want to address the problem in a simple way.
Could a "bionic pancreas"-a combination of insulin pump, continuous glucose monitor and predictive software-be on the market within four years? That 2017 date is the ambitious goal of a project from researchers at Boston University and Massachusetts General Hospital.
Researchers in Taipei, Taiwan, report that they have identified the top three drugs for reducing A1C levels in type 2 diabetes: biphasic insulin, GLP-1 analogs, and basal insulin. They hedged a little on their endorsement of GLP-1 analogs, however, by saying that although they are not decisively better at controlling A1Cs than other oral diabetes drugs, they have the advantage of helping to reduce weight without adding to the danger of hypoglycemia.
With tens of millions of American facing life with type 2 diabetes and many millions more at risk of the disease, scientists are scrambling to unravel novel treatments. The latest breakthrough could come from California's Salk Institute.
The FDA has approved US sales of JANUMET® XR, a daily oral treatment for type 2 diabetes that combines sitagliptin and extended-release metformin. The drug is the fourth oral type 2 diabetes treatment introduced by Merck, which also sells JANUVIA, JANUMET, and JUVISYNC.
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