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Recently, a Finnish study evaluated nearly 2,800 nondiabetic individuals, close to 500 of whom were using statins, after they had participated in a year of lifestyle interventions intended to improve their glucose metabolism. (Statins are lipid-lowering drugs that inhibit an enzyme crucial to the production of serum cholesterol; high cholesterol is associated with hardening of the arteries and cardiovascular problems.) The study was conducted by Dr. Nina Rautio and colleagues at Pirkanmaa Hospital in Tampere, Finland.
News from Danish pharmaceutical manufacturer Novo Nordisk reinforces the growing trend toward using a two-drug combination in the early treatment of type 2 diabetes. (See "A Conversation About Janumet and Earlier Combination Therapy for Type 2 Diabetes" for more discussion about this phenomenon.)
In a study it released in Lisbon, Portugal, at the recent meeting of the European Association for the Study of Diabetes, Novo said that combining its recently released drug Victoza® (liraglutide) with another drug early in therapy helps recently diagnosed type 2s achieve greater blood glucose control than they can with a single drug.
As we wrote back in 2008, the EndoBarrier is a very clever way to simulate the effect of a gastric bypass without the unpleasant scalpel part. It looks like a long clear plastic stocking, and it's simply threaded through the patient's mouth and stomach, down to the small intestine, where it lines the intestine's upper section (the same part that is bypassed in traditional surgery). Food slips right through it, but digestive enzymes are trapped on its other side. The two don't get to join forces until a couple of feet further downstream, so the effect on diabetes is a lot like that of a bypass: It resolves the symptoms of type 2 diabetes.
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