New Website Facilitates Communication Between Type 2 Patients and Their Physicians
People with type 2 diabetes often find visits with their physicians frustrating. Dr. Jeffrey Mechanick, MD, FACE, FACP, Secretary of the American Association of Clinical Endocrinologists (AACE), observes, "Many times when patients come to the doctor, the first thing that they say is really what's on their mind--that's their top priority. But oftentimes physicians don't address that at all. Instead, they move on to what's on their own agenda."
3 comments - Posted Jul 31, 2011
Be Thankful: A Letter of Gratitude
If you, like me, have diabetes, you realize upon reflection that you are, despite the constant demands of the disease, blessed. Somewhere, sometime, you have benefited from the kindness, professionalism, and genuine concern of a medical professional, be it a nurse, pharmacist, dietitian, physician, therapist, or supporting staff.
7 comments - Posted Apr 7, 2011
Does Coffee Protect Against Type 2 Diabetes?
Folks who need that morning cup of coffee to get going may be protecting themselves from type 2 diabetes, a new study suggests. UCLA researchers wrote in the journal Diabetes last month that drinking four cups of coffee a day reduced women's chance of developing type 2 by a bit less than half. What's more, the scientists point to a specific reason why all that java has a beneficial effect: a protein known as sex hormone-binding globulin (SHBG). Scientists have suspected for some time that SHBG was connected to diabetes development.
0 comments - Posted Feb 19, 2011
Mouse Study Eliminates Need for Insulin by Eliminating Glucagon
Can't make insulin? That might not be a problem, according to Dr. Roger Unger, the lead researcher on a mouse study out of UT Southwestern Medical Center. As Dr. Unger stated in a press release, his findings "suggest that if there is no glucagon, it doesn't matter if you don't have insulin....In adulthood, at least with respect to glucose metabolism, the role of insulin is to control glucagon. And if you don't have glucagon, then you don't need insulin...If diabetes is defined as restoration of glucose homeostasis to normal, then this treatment can perhaps be considered very close to a ‘cure.' "
1 comment - Posted Feb 16, 2011
Last Patient Completes the EU Phase III Study of Diamyd® Antigen Based Therapy for Type 1 Diabetes
The final patient has performed the last visit of the main study period in Diamyd Medical's European Phase III study. Treatment with the antigen based therapy Diamyd® is made to investigate whether beta cell function and thereby blood sugar control can be preserved in children and adolescents with new onset type 1 diabetes. The top line results from this study are expected to be reported as planned, in late spring 2011.
0 comments - Posted Feb 15, 2011
Type 1 Diabetes Associated With Common Cold Virus
It's generally thought that a genetic predisposition to type 1 diabetes is not enough to develop the disease, but that an environmental trigger is required to activate it. Researchers are not sure what that environmental trigger is, but enteroviruses have been under suspicion for quite a while. Enteroviruses are the second leading cause of viral colds in children.
1 comment - Posted Feb 8, 2011
"The Hormone of Darkness" Won't Come Out in the Light
Keeping the lights on all night might keep away the monsters under the bed, but it also keeps away the "hormone of darkness," melatonin, according to a new study in the Journal of Clinical Endocrinology and Metabolism. Melatonin, which is secreted into the blood by the brain's pineal gland at night, is involved in the circadian rhythm. Scientists believe that disrupting circadian rhythms can contribute to metabolic disease. Specifically, melatonin receptor genes have been linked to type 2 diabetes. Melatonin is also a powerful antioxidant that may help prevent cancer.
3 comments - Posted Jan 19, 2011
Surgeons Create Functional Artificial Pancreatic Tissue
In a proof-of-concept study presented at the 2010 Annual Clinical Congress of the American College of Surgeons, the researchers note that the matrix not only helps to understand the micro-architecture of the pancreas, but also prolongs the survival and preserves the function of the islets. Islets survived longer in the bio-artificial matrix than in conventional transplantation sites, and they produced significantly more insulin when challenged with glucose.
0 comments - Posted Oct 30, 2010
Continuous Glucose Monitoring Consensus Statement Released by AACE
JACKSONVILLE, FL - October 13, 2010 - The American Association of Clinical Endocrinologists (AACE) today published a consensus statement for continuous glucose monitoring (CGM) online, and will be published in the next issue of the association's official medical journal Endocrine Practice.
0 comments - Posted Oct 14, 2010
New Blood Markers for Type 2 Diabetes May Help to Identify Patients at Risk
For the first time, scientists have found that blood levels of some ribonucleic acids (microRNAs) are different among people with type 2 diabetes and those who subsequently develop the disease compared to healthy controls, according to research reported in Circulation Research: Journal of the American Heart Association.
0 comments - Posted Sep 22, 2010
Kids and Diabetes Risk: Do Chromosomes Hold New Clues?
Children who have a high risk of developing type 2 diabetes might be identified earlier by way of tell-tale genetic indicators known as biomarkers. Some of those new biomarkers might be pinpointed in research led by Nancy F. Butte and funded by the U.S. Department of Agriculture (USDA) and the U.S. Department of Health and Human Service's National Institutes of Health.
0 comments - Posted Sep 22, 2010
Rogue Protein May Trigger Diabetes
The presence of amyloid protein may produce a chain reaction which destroys vital insulin-producing cells. Researchers based in Dublin, writing in the journal Nature Immunology, say future drugs could target this process. Amyloid is implicated in many other diseases - most notably Alzheimer's.
0 comments - Posted Sep 17, 2010
Diabetes and Autoimmunity
The JDRF is celebrating its 40th anniversary this year. A lot has changed in the past four decades. One change has to do with the organization's name. JDRF stands for Juvenile Diabetes Research Foundation. Years ago we called what we now know as type 1 diabetes, Juvenile Onset Diabetes Mellitus (JODM). We called it that because we knew (or thought we knew) it was the kind of diabetes that occurred in children. We now know that type 1 diabetes occurs in people of all age groups. There was a lot we didn't know 40 years ago, one of which was that type 1 diabetes is an autoimmune disease.
0 comments - Posted Sep 16, 2010
Joslin 50-Year Medalists Give Clues to Cures
In type 1 diabetes, the body relentlessly attacks and destroys its own insulin-producing pancreatic beta cells. But a study by Joslin Diabetes Center scientists now has firmly established that some of these cells endure for many decades in a small group of people with the disease-offering clues to potential treatments for preserving and even restoring the crucial cell population.
0 comments - Posted Sep 14, 2010
Vietnam Vets, Agent Orange, and Type 2 Diabetes
Despite the lack of a strong link between type 2 diabetes and Agent Orange, the government is paying Vietnam veterans hundreds of millions of dollars for the disease on the basis of Agent Orange exposure.
2 comments - Posted Sep 12, 2010
More from ACCORD
In people with longstanding type 2 diabetes who are at high risk for heart attack and stroke, lowering blood sugar to near-normal levels did not delay the combined risk of diabetic damage to kidneys, eyes, or nerves, but did delay several other signs of diabetic damage, a study has found. The intensive glucose treatment was compared with standard glucose control.
0 comments - Posted Jul 2, 2010
Coconut Oil Could Reduce The Symptoms Of Type 2 Diabetes
A diet including coconut oil, a medium chain fatty acid (MCFA), helps combat insulin resistance. Insulin resistance is the inability of cells to respond to insulin and take in glucose for energy. The pancreas tries to compensate for insulin resistance by producing even more insulin, but eventually glucose accumulates in the bloodstream. Over time, insulin resistance and obesity can lead to pre-diabetes or full-blown type 2 diabetes.
0 comments - Posted Jul 1, 2010
Double Transplantation Treatment for Type 1 Diabetes
City of Hope researchers have found that bone marrow transplantation with islet cell transplantation shows promise as a treatment for late-stage type 1 diabetes. This combination may enable patients to make their own insulin again. Results from laboratory research led by Defu Zeng, MD, associate professor in the departments of Diabetes Research and Hematology & Hematopoietic Cell Transplantation at City of Hope, were published online this month in the journal Diabetes.
0 comments - Posted Jun 25, 2010
Scientists Have Found the Peptide Trigger for Type 1 Diabetes in Animal Tests
Researchers from the National Jewish Health and University of Colorado Anschutz Medical Campus have found a specific protein fragment, or peptide, that stimulates an immune system attack resulting in diabetes. Their experiments in mice contradict conventional wisdom about such peptides and support work by scientists studying autoimmune diseases.
0 comments - Posted Jun 24, 2010
Dieting to Reduce Diabetes Risk May Not Work in People With Low Muscle Mass
One of the factors that increases the risk of acquiring type 2 diabetes is excess body fat. So it makes sense that losing weight has always been one of the first lines of defense against the disease. Yet people who are slender -skinny, even- sometimes develop type 2. Why is that? Does the fact that a slender person can acquire type 2 negate the need for weight control?
0 comments - Posted Jun 18, 2010
DKA and Infection Risk
Diabetic ketoacidosis poses enough of a threat on its own. But in a small number of cases, it leaves sufferers open to a potentially fatal infection called mucormycosis.
0 comments - Posted Jun 12, 2010
Safe Chemicals Act of 2010 and You
We all know that certain chemicals in everyday products are harmful: mercury and lead, just to name a couple. But how harmful, and what can we do about it?
0 comments - Posted Jun 9, 2010
Environmental Factors In Diabetes
Both genetic components and environmental factors play a role in most chronic diseases, including type 2 diabetes. In the same way that researchers use a Genome-Wide Association Study (GWAS) to evaluate the role of genetic factors in disease, scientists at Stanford University have used an Environmental-Wide Association Study (EWAS) to evaluate environmental factors on diabetes.
0 comments - Posted May 29, 2010
Skimping on Sleep Linked to Diabetes and Higher Mortality Rates
As awareness of pre-diabetes grows, the list of conditions that can lead to it seems to be growing. Along with obesity and a sedentary lifestyle, researchers may start listing lack of sleep as another danger signal. Two recently published studies conclude that sleep deprivation can lead to insulin resistance-a precursor for diabetes-and even increase the risk of early death.
0 comments - Posted May 26, 2010
Beware the Perils of Severe Hypoglycemia
Over 80 years ago, famed diabetologist Elliot Joslin said about the treatment of patients with type 1 diabetes: "Ketoacidosis may kill a patient, but frequent hypoglycemic reactions will ruin him." Unfortunately, hypoglycemia continues to be the most difficult problem facing most patients, families, and caregivers who deal with the management of type 1 diabetes on a daily basis. Frequent hypoglycemia episodes not only can "ruin," or adversely impact the quality of life for patients, but also, when severe, can cause seizures, coma, and even death.
13 comments - Posted May 13, 2010
Recruiting Patients with Newly Diagnosed Type 1 Diabetes
Dr. Richard Hays announced today that he is now recruiting children with newly diagnosed type 1 diabetes for Protégé Encore, a randomized, placebo-controlled Phase III clinical trial. This is the second of two Phase III studies testing the safety and efficacy of an investigational drug called teplizumab. The first study, known as Protégé, has completed enrollment of more than 530 subjects with type 1 diabetes. There is currently no approved therapy to slow the progression of type 1 diabetes.
0 comments - Posted May 12, 2010
Stem Cell Treatment for Type 1 Diabetes
Osiris Therapeutics announced that it has been granted Orphan Drug designation from the U.S. Food and Drug Administration (FDA) for Prochymal as a treatment for type 1 diabetes mellitus. The FDA instituted the Orphan Drug Act to promote the development of treatments for underserved patient populations. To be eligible for Orphan Drug designation, the treatment must target a disease that affects fewer than 200,000 new patients per year in the United States.
0 comments - Posted May 7, 2010
Thinking of Kids? Here’s Some Tips for Handling Pregnancy & Diabetes
Becoming pregnant for the first time can be overwhelming for any woman, especially if that woman has diabetes. When my husband and I decided we were ready to have children, the first thing I did was make an appointment with my endocrinologist. Diagnosed when I was fourteen, I've had type 1 diabetes for twenty-four years. My doctor explained that I would need to be in tight control for three months before I could even think about babies, so I got right to work. Learning everything I could about diabetes and pregnancy, I was pleased to discover that with education, support, and practice, a woman with diabetes has every opportunity for a healthy pregnancy.
7 comments - Posted Nov 17, 2008
Family with Nine Kids, Three with Type 1, Finds There Are Some Silver Linings
My husband and I have nine children. Elliott is our oldest and when he was diagnosed with type 1 at age 11 in 1996, we were blindsided. Neither my husband, nor I, nor anyone in our extended family had diabetes. Elliot had all of the classic symptoms: excessive thirst, frequent urination, uncontrollable hunger, occasional blurry vision, and (something I think a lot of parents don't recognize as a sign) bedwetting.
11 comments - Posted Aug 28, 2008
Annual List of America's Best Hospitals Released
“Let’s take care of the patient.” That must be the credo of hospitals that make U.S. News & World Report's “Best Hospitals” rankings, in which hospitals are judged not in routine procedures but in difficult cases across an entire specialty. In the nineteenth year of this annual review, hospitals are ranked in 16 specialties, from cancer and heart disease to respiratory disorders and urology. Out of the 5,453 hospitals put through a rigorous statistical mill, only 170 scored high enough to appear in any of the specialty rankings.
2 comments - Posted Jul 17, 2008
A Leading Pediatric Endocrinologist Talks About Kids: Keeping BGs Steady
What’s the most important goal for kids and families dealing with diabetes? Learn all you can, and then strive for the best possible blood glucose levels without excessive hypoglycemia. This is a tough goal to attain. Our tools, food, insulin, and monitoring, while the best they have ever been, are still imprecise. And although optimal glucose control is critical for immediate and long-term health, one must always be wary of severe and recurring hypoglycemia.
0 comments - Posted Apr 13, 2007
Interview with a Pediatric Endocrinologist: Dr. Morey Haymond
Q: Please describe your background.
Morey Haymond: A pediatric endocrinologist by training, I have been involved in
metabolic studies of kids, infants, and adults for 35 years. I work with children who have disorders of
carbohydrate metabolism, including diabetes and hypoglycemia. Understanding the regulation of those
processes has been a focus of my research, and I have looked at amino acid and fat metabolism as well.
1 comment - Posted Mar 29, 2007
Help Wanted: Pediatric Endocrinologists
"Now is a wonderful time to consider a research career in childhood diabetes," says Georgeanna Klingensmith, MD, who heads the Division of Pediatrics at the Barbara Davis Center at the University of Colorado Health Sciences Center. "We need young people with energy and enthusiasm to take these new findings in molecular biology, genetics, and immunology and put them together to move the field ahead."
0 comments - Posted May 1, 2003
Choosing an Exercise Shoe
The type of shoe you choose for your walking or running activity may be the single best insurance you can buy to reduce your chance of injury. I find that most people look for two things in a shoe: cushion and style. The problem here is that cushion, while it may feel good initially, does not offer the stability that most people need. A lack of stability in a shoe can cause the majority of weight-bearing injuries to the ankles, knees, hips and lower back. Remember, it is nice to look good while you are exercising, but how can you continue to look good if you are injured?
0 comments - Posted Apr 1, 2002
Interpreting Your C-peptide Values
Normal C-peptide levels for a fasting test are generally considered to be anything between 0.5 nanograms (ng) per millileter (ml) and 3 ng/ml, although people who do not have diabetes may occasionally stray out of this range. The following is a range of C-peptide values in people without diabetes, as compiled by Endocrine Sciences, Inc., a California-based laboratory that conducts the test. It should be noted that, in some cases, subjects fell below the normal range of C-peptide values, but were still not found to have diabetes. The range of values may also vary according to what lab your health care practitioner uses.
11 comments - Posted Sep 1, 2000
Metformin: Who Should Take It?
Several prominent endocrinologists gathered in San Diego this past January to develop guidelines for prescribing metformin. Speaking at the American Diabetes Association Post-Graduate course were: Alan J. Garber, MD, PhD, of Houston's Baylor College of Medicine; Ralph A. DeFronzo, MD, Chief of the Diabetes Division of the University of Texas Health Center in San Antonio; and Jay S. Skyler, MD of Miami.
0 comments - Posted Jul 1, 1995
Vital Energy: A Scientific View of Diabetes
Diabetes is a disease of the substance sugar, but is really about energy. In the final analysis, diabetes is a disease of poor energy metabolism. It is manifest in problems with sugar, the crucial fuel, and insulin, the crucial energy hormone. To understand diabetes, we need to understand biological energy: where it comes from, what it is, and how it works.
0 comments - Posted Sep 1, 1991