An Italian-based pharmaceutical company with subsidiaries in New York has been granted orphan drug status for a new drug to treat neurotrophic keratitis, a rare degenerative corneal disease that impacts less than 1 in 5,000 people worldwide.
It was more than two decades ago, and Penny Hildreth was already feeling overwhelmed by life when she learned that she had type 1 diabetes. She was pregnant with her second child and worried about the baby’s safety after a car accident that had left Hildreth with a broken collarbone, a broken rib, and a punctured spleen. It was the spleen injury that ultimately led to her diagnosis of diabetes, but she was more concerned about the baby, a little girl who was born healthy despite the automobile accident. “I always say that she’s my miracle,” says the 46-year-old Portland resident.
The Mayo Clinic Health Letter for August 2012 has published three lifestyle changes that could stave off the progression of prediabetes to full-blown type 2 diabetes. The list isn't new, but its periodic reiteration indicates that healthcare researchers and providers have settled on a simple prescription for staying diabetes-free.
Diabetes affects nearly 25 million Americans, and that number is expected to grow substantially every year. It's the fifth leading cause of death in America, more than breast cancer and AIDs combined. And according to a report released last week from the Agency for Healthcare Research and Quality (AHRQ), it's a disease that’s costing Americans $83 billion a year in hospital fees — 23 percent of total hospital spending.
NeuroMetrix, Inc., a Massachusetts-based medical device company, has filed a 510(k) form with the US Food and Drug Administration for the SENSUSTM, a pain therapy device for people who suffer diabetic neuropathy. A 510(k) is a "premarket notification" of a company's intent to market a medical product. The FDA then tests the product and provides feedback to the manufacturer. Once the FDA clears the product, its maker can introduce it to the US market.
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