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Latest Research Articles
For people with type 1 diabetes who follow medical research, development of a closed-loop, "artificial pancreas" has always been the Holy Grail. Such a system would combine an insulin pump with a continuous glucose monitor to provide constant control of blood glucose levels. But what if such a system was only a start? What if it might work better when combined with another therapy altogether?
1 comment - Posted Dec 5, 2013
Research has already shown that gastric bypass can ease symptoms of diabetes, but according to a new study, a less-invasive sleeve may also result in benefits for those with type 2 diabetes.
0 comments - Posted Nov 29, 2013
One of my job as a member of the Diabetes Health staff is to manage the comments section on our website. Sometimes the comments get heated, and when they do certain patterns emerge.
4 comments - Posted Nov 28, 2013
Researchers at North Carolina State University and the University of North Carolina at Chapel Hill have are looking at nanoparticles and ultrasound as a way to do away with the need for daily injections of insulin via syringes and needles.
4 comments - Posted Nov 24, 2013
According to researchers, applications that help patients manage their diabetes are among the top 10 apps doctors suggest to their patients.
0 comments - Posted Nov 20, 2013
A new drug being developed by Eli Lilly Co. that duplicates the effects of a hormone may soon be added to the growing arsenal of pharmaceutical weapons available to treat type 2 diabetes.
0 comments - Posted Nov 16, 2013
According to results of a new study, high levels of serum calcium - the calcium that shows up in extracellular fluid or muscle tissue - could be linked to type 2 diabetes.
0 comments - Posted Nov 12, 2013
If you like taking an afternoon power nap as a way to recharge, make sure it's a short one.
2 comments - Posted Nov 6, 2013
The National Institutes of Health is investing millions of dollars in new research to determine if vitamin D supplements play a role in preventing type 2 diabetes.
0 comments - Posted Nov 5, 2013
It's always fun to get a different take on things. You sit for years a few rows up from first base and then one day you decide to go sit out by left field. Who knew the game could look so different?
2 comments - Posted Nov 3, 2013
A German research team calls it "the sweet melody of glucose."
0 comments - Posted Oct 28, 2013
The US Patent Office has issued a patent to Massachusetts-based Aphios Corporation for the oral delivery of insulin.
1 comment - Posted Oct 26, 2013
Comedian Robin Williams got his start on TV in 1978 in the comedy "Mork and Mindy," about a wacky alien, Mork (Williams), who comes to live in a boarding house run by a cute young woman (Pam Dawber). In that popular sitcom, Mork would always greet people by saying, "Nanu, Nanu," which was "Hello" on his home planet of Ork.
0 comments - Posted Oct 23, 2013
The National Institutes of Health recently listed brittle type 1 diabetes as a rare disease, a distinct and separate form of type 1. An estimated 3,700 to 8,700 persons in the United States have the condition.
4 comments - Posted Oct 19, 2013
A Massachusetts-based research firm concludes that the first-world market for type 2 drugs and treatments will increase from $27 billion in sales in 2012 to $47 billion in 2022.
0 comments - Posted Oct 18, 2013
Massachusetts-based GI Dynamics, Inc. says it is currently enrolling subjects at 17 sites across the United States for its clinical trial of the EndoBarrier for people who have uncontrolled type 2 diabetes and are obese. The company expects to enroll approximately 500 people who meet the enrollment criteria at up to 25 sites in the United States.
0 comments - Posted Oct 15, 2013
SACRAMENTO, Calif. -- UC Davis Health System researchers have identified for the first time a biological pathway that is activated when blood sugar levels are abnormally high and causes irregular heartbeats, a condition known as cardiac arrhythmia that is linked with heart failure and sudden cardiac death.
1 comment - Posted Oct 14, 2013
Few treatments for type 1 diabetes have been as elusive and long-promised as inhalable insulin. The concept has always sounded remarkable: Instead of jabbing themselves with needles, type 1s (and insulin-using type 2s) could take a quick puff on an inhaler to get a dose of insulin.
1 comment - Posted Oct 12, 2013
People with type 2 diabetes and those heading toward that diagnosis may face a quicker decline in their beta cell function than previously understood, according to a new study published in the Journal of Clinical Endocrinology & Metabolism. That means the progress and challenges for such patients may progress more quickly than doctors expects and need more aggressive treatment.
0 comments - Posted Oct 9, 2013
One of the most intriguing areas of type 1 diabetes research focuses on newly diagnosed patients. Given that the disease occurs after an autoimmune response damages the body's insulin-producing beta cells, scientists have looked to new type 1s as fertile ground for experimentation.
4 comments - Posted Oct 8, 2013
According to researchers, dapagliflozin, a diabetes drug developed jointly by two pharmaceutical companies has shown significant benefits when teamed with metformin and sulfonylurea.
0 comments - Posted Sep 28, 2013
When it comes to research, you would expect that the wants of those living with type 1 diabetes would be totally in line with the goals of scientists seeking a cure for the disease.
12 comments - Posted Sep 24, 2013
A drug traditionally used to treat age-related macular degeneration has been successful in also treating diabetic macular edema in recent trials.
0 comments - Posted Sep 20, 2013
If you Google "type 2 diabetes drugs," one website lists the names of 92 drugs that medical professionals have prescribed at one time or another to treat diabetes.
1 comment - Posted Sep 17, 2013
People with type 2 diabetes who use insulin to help control elevated blood sugar might be able to end their dependence on it if new research progresses.
2 comments - Posted Sep 11, 2013
Is it important to determine the exact type of diabetes you have if you're already on insulin and maintaining very good blood sugar control, and if so, why?
0 comments - Posted Aug 21, 2013
Community health workers who provide diabetes education often lack information on how this disease affects the eyes. In response, the National Eye Health Education Program of the National Eye Institute has developed a new interactive online training course to help CHWs better understand the eye complications that diabetes can bring.
0 comments - Posted Aug 20, 2013
Hard-to-treat toenail fungus is one side effect of diabetes, a condition brought by decreased circulation and increased susceptibility to infection. The condition, called onychomycosis, afflicts some 35 million people in the United States.
0 comments - Posted Aug 19, 2013
BALTIMORE-Researchers at the University of Maryland School of Medicine are enrolling patients with type 2 diabetes into an NIH-funded clinical trial to evaluate the long-term benefits and risks of four widely used diabetes drugs in combination with metformin, the most common first-line medication.
0 comments - Posted Aug 18, 2013
British snowboard champion Christopher Southwell has always lived for the adrenaline rush.
0 comments - Posted Aug 16, 2013
I can only speak as a type 2. I don't for a second think that the problems I encounter managing my diabetes compare to what people with type 1 go through.
8 comments - Posted Aug 9, 2013
New research suggests that type 1s' personality types could affect their mortality risk. While that might sound peculiar at first, the research results-culled from 22 years of study-make some important connections.
0 comments - Posted Aug 5, 2013
Type 1 diabetes doesn't happen all at once. Scientists have shown that it's usually a gradual process, in which the insulin-producing beta cells eventually fade out. So wouldn't it be marvelous if the function of those beta cells could be preserved, allowing people newly diagnosed with diabetes to produce some of their own insulin for a longer time?
4 comments - Posted Aug 3, 2013
Could a "bionic pancreas"-a combination of insulin pump, continuous glucose monitor and predictive software-be on the market within four years? That 2017 date is the ambitious goal of a project from researchers at Boston University and Massachusetts General Hospital.
1 comment - Posted Aug 2, 2013
Physicians may be able to predict if diabetic patients will develop peripheral neuropathy, thanks to results of new research.
0 comments - Posted Aug 1, 2013
The U.S. Food and Drug Administration has announced that it has issued letters warning 15 U.S. and foreign companies to cease sales of products that the agency has determined are being illegally marketed.
1 comment - Posted Jul 27, 2013
Carrie Miller had one goal when she was a child-become the female counterpart to Indiana Jones. If nothing else, she wanted to live a life infused with that blockbuster's level of adrenaline rush.
0 comments - Posted Jul 22, 2013
A British drug company is looking to medical marijuana- or at least a derivative of it-to help treat a variety of different diseases, including type 2 diabetes.
2 comments - Posted Jul 20, 2013
Insulin pump maker Animas has taken another step toward perfecting (and hopefully putting on sale) the first artificial pancreas. The company doesn't call it anything that clear-cut, instead referring to the device as "a closed-loop insulin delivery system."
7 comments - Posted Jul 17, 2013
While there is still no cure for diabetes, there is a growing number of therapies available to those battling the disease-and even more are in the works, according to experts who spoke at a recent symposium.
2 comments - Posted Jul 13, 2013
Massachusetts-based Zafgen, a biopharmaceutical company devoted to treating obesity, may have taken a big step toward making the growing health concern obsolete.
0 comments - Posted Jul 9, 2013
Will people with type 1 diabetes ever see an end to their need for insulin?
6 comments - Posted Jul 7, 2013
A new, first-in-its-class drug for type 2 diabetes has just been approved by the Food and Drug Administration. Invokana works by blocking re-absorption of glucose by the kidneys and stimulating urination, which removes glucose from the bloodstream.
1 comment - Posted Jun 27, 2013
CHICAGO, June 24, 2013 /PRNewswire/ -- Key results from the global Diabetes Attitudes, Wishes and Needs 2 study (DAWN2TM) show that one in five people with diabetes feel discriminated against because of their condition, and support from the broader community is scarce. Results from the DAWN2 study were presented at the 73rd Scientific Sessions of the American Diabetes Association (ADA). DAWN2 represents opinions from more than 15,000 people living, or caring for people, with diabetes in 17 countries across four continents.
0 comments - Posted Jun 26, 2013
The main question that doctors---and patients---ask about a prescription drug is simple: Does it work? Does this medicine improve the condition it's prescribed for?
0 comments - Posted Jun 25, 2013
It's a nightmare scenario for a person who's been newly diagnosed with diabetes: You're fired after learning you have this chronic-yet-manageable disease. Everything the doctors told you about living a nearly normal life seems like a lie. Your visions and hopes for the future-already clouded with this scary medical news-darken.
4 comments - Posted Jun 24, 2013
Life never stops. It's a truism that people with diabetes of all types know too well. Your responsibilities change. Your duties at your job shift. The people around you change. And you have to make the best you can of it all, racing to keep up and adjusting your treatment plan as best you can. It's exhausting.
0 comments - Posted Jun 19, 2013
Can Januvia Trigger Cancer Symptoms?
1 comment - Posted Jun 12, 2013
On some days living with a chronic disease and all its complexities for 15 years has the ability to force me into hiding.
3 comments - Posted Jun 11, 2013
About five years ago during a visit to a local endocrinologist, he asked if I might be interested in participating in a Phase 3 study of a new type 2 drug. It didn't take long for me to say yes, especially once he explained how being a study subject worked.
2 comments - Posted Jun 10, 2013
A significant majority-20 of 26 members attending a combined meeting of FDA advisory committees-has voted to modify or remove the current restrictive label and distribution regulations affecting the type 2 drug Avandia.
0 comments - Posted Jun 9, 2013
People with diabetes know the score. We've all seen "revolutionary" drugs and treatments introduced with fanfare, and we know that that much of the time they're evolutionary at best. But something has changed in the world of diabetes care.
3 comments - Posted Jun 1, 2013
Two new drugs originally developed by Eli Lilly are showing promise when it comes to treating type 2 diabetes.
1 comment - Posted May 19, 2013
The restriction of protein intake is an outdated thought. It was born of a study by Barry Brenner, at Harvard, back in the 1980s. He did a survey of the diabetologists in Boston asking, "At what blood sugars do you like to keep your diabetics?" The collective answer ultimately was 250 mg/dl.
0 comments - Posted May 1, 2013
Obese patients hoping to slim down with bariatric surgery may soon be able to get the weight-loss effects of gastric bypass without going under the knife, according to a new study.
0 comments - Posted Apr 21, 2013
The FDA recently approved the next-generation OmniPod from Insulet, giving people with insulin-dependent diabetes an even less invasive way to manage their diabetes.
0 comments - Posted Apr 19, 2013
So what do those long hours on nursing duty mean when it comes to the quality of healthcare we receive? When it comes to overworked nurses, it leads to a higher risk of mistakes, according to a new study.
0 comments - Posted Apr 18, 2013
Hikes to the beach, overnight camping, swimming, playing sports, an exhilarating run on the zip line, songs and skits by the campfire. Friends for life. This is the magic of camp, and diabetes camp is no exception.
0 comments - Posted Apr 13, 2013
In my experience the most common cause of elevated cholesterol is low thyroid. High blood sugars also have an effect on LDL that can be very dramatic. If someone has elevated cholesterol, diabetic or not, the very first thing you do is check their free and total T3, and free and total T4. When you give them adequate thyroid replacement, the LDL usually normalizes.
0 comments - Posted Apr 12, 2013
The key to encouraging people to choose healthier foods is to make good-for-you items more affordable, according to a new study.
0 comments - Posted Apr 11, 2013
Diabetes can seem complicated and overwhelming, full of charts and devices and concerned-looking medical professionals. There's talk of hormones and endocrine systems, of obscure organizations and dietary plans.
6 comments - Posted Apr 4, 2013
This person is referring to the ACCORD study, which in its initial unsophisticated scoring supposedly showed that a large group of elderly diabetics who had existing heart disease, died sooner when their A1cs were brought down.
1 comment - Posted Apr 2, 2013
New stem cell research may take a step toward preventing amputations in people with diabetes, according to a new study out of Ireland.
0 comments - Posted Mar 26, 2013
A protein linked to inflammation could predict the risks of two eye-related diseases common in people with diabetes, according to the results of two new studies.
0 comments - Posted Mar 24, 2013
Don't get enough sleep? According to a small, new study, this may make you eat larger portions of high-calorie foods and, accordingly, increase your risk of gaining weight.
0 comments - Posted Mar 18, 2013
Accountable Care Organizations, it seems, haven't won over 100 percent of all physicians.
0 comments - Posted Mar 14, 2013
Although some Continuing Medical Education (CME) is aimed at helping doctors improve communication skills, more doctors should get involved.
0 comments - Posted Mar 12, 2013
Researchers in California may have taken a big step in the fight to end renal cancer.
0 comments - Posted Mar 8, 2013
Research into a cure for type 1 diabetes proceeds on several fronts. One interesting approach is seeking ways to manipulate the autoimmune system to prevent the body's mistaken destruction of pancreatic beta cells. Another tack is the transplantation of pancreatic tissue, either from human cadavers or carefully isolated "clean" pigs that have been specially raised for the purpose.
0 comments - Posted Mar 7, 2013
I heart carbohydrates, and sometimes, I hate carbohydrates.
0 comments - Posted Feb 18, 2013
Tandem Diabetes Care, Inc. has teamed with Dexcom to expand an existing partnership to include development of Dexcom’s latest continuous glucose monitoring system, the G4 Platinum. The U.S. Food and Drug Administration approved the new CGM in October.
0 comments - Posted Feb 17, 2013
Researchers at the Dana-Farber Cancer Institute in Boston report that they have discovered a naturally occurring hormone that can direct the body to burn more calories and increase its insulin sensitivity. Their results, based on lab experiments with mice, could potentially lead to therapies for diabetes, obesity, and even muscular dystrophy.
3 comments - Posted Feb 10, 2013
Here's a bit of news that, if conclusively proven, could gladden the hearts of everybody who struggles to get into a regular exercise habit: British researchers say that short 30-second bursts of intense activity, adding up to only 3 minutes per week, duplicate the effects of much longer gym workout or track running routines.
0 comments - Posted Feb 8, 2013
In a 10-5 vote, an FDA panel has recommended that the agency approve the marketing of Johnson & Johnson's InvokanaTM (canagliflozin), an oral once-daily drug for treating type 2 diabetes in adults.
0 comments - Posted Feb 1, 2013
You're a person with diabetes who has just learned that you've been diagnosed with cancer. Which disease should take precedence in your life?
0 comments - Posted Jan 25, 2013
On September 26, 1992, my daughter Kaitlyn was diagnosed with type 1 diabetes. Since that time, we have immersed ourselves in the world of diabetes with two goals: First, to ensure that Kaitlyn has the very best tools, both medical and emotional, to manage her diabetes, and second, to dedicate our unyielding efforts in pursuit of a cure. For us, it's not either/or: It's both.
2 comments - Posted Jan 21, 2013
A Chinese research study of diabetes patients with coronary heart disease concludes that metformin is more effective than glipizide in reducing the risk of major cardiovascular events, such as stroke and heart attack.
0 comments - Posted Jan 20, 2013
Earl "the Pearl" Monroe was one of the greatest guards in the history of the National Basketball Association, playing from 1967 through 1980 for the Baltimore Bullets and the New York Knicks. A member of the NBA's 50th Anniversary All-Time Team, he was enshrined in the league's Hall of Fame in 1990. The Knicks retired his jersey number, 15, in 1986.
0 comments - Posted Jan 14, 2013
Forty-three year old stage and TV actor Stephen Wallem is a jack of all trades when it comes to entertainment. Best known for his one-man musical review, "Off the Wallem," he is also a playwright, composer, and director. Currently, he plays Thor, a gay nurse with type 1 diabetes, on the Showtime series "Nurse Jackie."
3 comments - Posted Jan 12, 2013
Education as part of routine care is the key to successful treatment of type 1 diabetes, according to a new study from researchers in the United Kingdom.
0 comments - Posted Dec 9, 2012
Taking linagliptin seems to help protect the kidneys in people with type 2 diabetes. The drug, usually used along with diet, exercise, and sometimes other medications, lowers blood sugar levels by increasing the amounts of certain natural substances in the blood.
0 comments - Posted Dec 8, 2012
Mindful eating may help control weight as well as blood sugar levels in people with diabetes.
1 comment - Posted Dec 5, 2012
The study, conducted by Pei-Chun Chen, Ph.D., of the National Taiwan University College of Public Health in Taipei, and colleagues, followed two groups: one consisting of an equal number of people with and without diabetes, and the other consisting of equal numbers of people with and without clinical depression.
0 comments - Posted Dec 3, 2012
New research reveals that those suffering from depression might be more likely to develop type 2 diabetes.
0 comments - Posted Dec 3, 2012
Danish researchers report that high levels of transferrin may contribute to the destruction of insulin-producing beta cells in the pancreas. Transferrin is a glycoprotein that binds with iron and transfers it to cells.
1 comment - Posted Nov 28, 2012
Australian researchers have released a study on stem cells that potentially could lead to type 1s being able to make their own insulin, erasing the need for regular injections.
1 comment - Posted Nov 27, 2012
Scientists at Tel Aviv University in Israel report that taking whey protein isolates or concentrates may help treat type 2 diabetes and prevent obesity.
0 comments - Posted Nov 25, 2012
Good news for Eli Lilly & Co., as well as for type 2s who appreciate the addition of new drugs to treat their condition: Lilly says its once-weekly injectible drug, dulaglutide, has outperformed three other widely taken diabetes drugs in three just-concluded Phase III studies.
0 comments - Posted Nov 20, 2012
A Chinese study of 345 patients divided between non-diabetics and people with type 2 diabetes concludes that gut bacteria between the two groups differs substantially-so much so that the bacteria can be used to accurately determine who has or doesn't have the disease.
0 comments - Posted Nov 18, 2012
The FDA has approved U.S. sales of Dexcom's G4TM PLATINUM continuous glucose monitor. The San Diego-based manufacturer said it is taking orders and plans to begin shipping the device to patients within the next few weeks.
2 comments - Posted Nov 16, 2012
To see if tightly controlling blood sugar provides improved results in patients who received a kidney transplant, a group of diabetic post-transplant patients were followed for three days. A subset of the randomly assigned group had their blood glucose kept in tight range with IV insulin, while a control group received insulin as they ordinarily would, via injections.
0 comments - Posted Nov 14, 2012
It started at 7:45 a.m., when I heard my husband's phone alarming. Since it was his scheduled virtual type 1 for a day challenge with JDRF, I grabbed the phone as he kept snoring. Sure enough, it was his first text from JDRF, reminding him to gather his testing supplies before leaving the house. I shook his leg. "Wake up, sleepy, you have a text about your diabetes." He lay there, continuing to snooze. I tried again with "C'mon, you have to get up, your diabetes needs you!" He hollered between snores, "My diabetes is fine!" Oh, how I wish I could silence my diabetes in the morning with those words.
3 comments - Posted Nov 13, 2012
People with diabetes who receive treatment for gum disease can enjoy substantial reductions in hospitalizations, doctor visits, and annual medical expenses according to a study conducted by the University of Pennsylvania and dental insurer United Concordia Dental.
0 comments - Posted Nov 12, 2012
I recently learned of a JDRF campaign to increase type 1 diabetes awareness, in which people without diabetes can sign up to experience “virtual diabetes” for a day. During that day, they receive up to 24 texts prompting actions that simulate the frequent blood sugar testing, insulin injections, and dietary choices that people with type 1 diabetes must endure. JDRF thoughtfully notes on its website that “while no virtual campaign can re-create the many needles required or the physical and financial tolls of this serious disease, T1D for a Day seeks to deepen understanding of the many heroic steps our friends and loved ones with T1D take each day.”
1 comment - Posted Nov 9, 2012
While there is an almost constant media drumbeat about the dangers of obesity and overweight, it's a pleasure to learn that not everyone who is overweight is in bad health or runs the risk of it.
0 comments - Posted Nov 7, 2012
Good news for Eli Lilly & Co., as well as for type 2s who appreciate the addition of new drugs to treat their condition: Lilly says its once-weekly injectible drug, dulaglutide, has outperformed three other widely taken diabetes drugs in three just-concluded Phase III studies.
0 comments - Posted Nov 5, 2012
A Swedish study has found that even less than a 1% reduction in A1c's lowered the mortality rate among type 2 patients by 50 percent compared to patients whose A1c's remained stable or increased. (Mortality was defined as the likelihood of dying from any cause within the next five years.)
0 comments - Posted Nov 3, 2012
Stan Bush wasn't really surprised to find out he had type 2 diabetes. An unhealthy diet that regularly featured containers of ice cream before bed had left him primed for the disease. But how he handled the news was a surprise, at least to his doctor.
0 comments - Posted Nov 2, 2012
Do people on the high end of the normal range of blood sugar levels develop the same brain shrinkage and tendency toward dementia that has been found in those with type 2 diabetes? According to an Australian study, the answer appears to be yes.
0 comments - Posted Nov 1, 2012
I’m very happy to announce Diabetes Health’s partnership with CVS/pharmacy and welcome you to ExtraCare Advantage for Diabetes® from CVS/pharmacy®. If you have diabetes and already have a CVS/pharmacy ExtraCare® card, ExtraCare Advantage for Diabetes offers even more benefits.
0 comments - Posted Oct 24, 2012
Author’s note: Throughout this series, I will inject my own opinion, which frequently differs from that of the medical establishment in this field. Having had diabetes for more than 66 years, I place my emphasis on the well-being of fellow patients.
0 comments - Posted Oct 21, 2012
When people with diabetes are successful and happy, their situation is often viewed as having been achieved despite the obstacle of diabetes. I am advocating for a shift in that perception. What if instead of seeing all the good in our lives as existing despite our disease, we begin to see everything that we are—the challenges and the achievements—as a direct product of all that we are made up of, diabetes included?
2 comments - Posted Oct 14, 2012
Like the taste of cinnamon? If you do and you have type 2 diabetes, a daily cinnamon supplement may help control your condition.
0 comments - Posted Oct 12, 2012
When I became a type 2 diabetic, I wanted to find a way to manage my weight and blood sugar with diet and exercise. I tried the high carb diet recommended by my doctor and dietitian for a time. It worked wonderfully well while my blood sugar level was high, but when my blood sugar stabilized and I was able to go off medication, I started gaining weight again. The next thing I tried was low carbohydrate dieting. I found it to be a very effective way to lose weight rapidly, but I was unable to endure the regimen for more than a short time.
6 comments - Posted Oct 2, 2012
Philadelphia-based Echo Therapeutics plans to introduce a needle-free continuous glucose monitoring system to the US market in 2013, pending FDA approval. The Symphony® tCGM is a two-part device that monitors blood glucose by taking readings through a user’s skin rather than via finger pricks. It is intended for use by anyone with diabetes, not just insulin pump users.
2 comments - Posted Sep 26, 2012
German scientists report that gestational diabetes and/or low income may increase a child’s risk of attention deficit/hyperactivity disorder (ADHD). However, the study indicates, breastfed children born under those conditions may gain some protection against ADHD.
0 comments - Posted Sep 20, 2012
A British study of type 2 men reports that although testosterone therapy had a beneficial effect on blood glucose levels and other metabolic indicators for non-depressed men, those suffering from depression experienced no benefit. In fact, reports Geoffrey Hackett, MD, at Good Hope Hospital in Sutton Coldfield, depressed men actually experienced a worsening of symptoms.
0 comments - Posted Sep 18, 2012
Sometimes it isn’t a stranger or acquaintance giving you a hard time about your diabetes. Sometimes it’s a family member or close friend that says something hurtful about your diabetes management. And that is far more difficult to hear than the guy at the table next to you in a restaurant or some lady sharing an office with you at work.
14 comments - Posted Sep 13, 2012
A new blood test can predict which patients with heart failure are likely to need an internal implantable defibrillator that can treat abnormal heartbeat and prevent sudden death.
0 comments - Posted Sep 12, 2012
The US Food and Drug Administration has approved US sales of NUCYNTA® ER (tapentadol), a twice-daily extended-release oral analgesic for the treatment of pain from diabetic peripheral neuropathy. The drug, produced by New Jersey-based Janssen Pharmaceuticals, Inc., provides around-the-clock management for moderate to severe chronic neuropathic pain. Janssen says that it is currently the only opioid on the US market that has been approved for treating the condition.
1 comment - Posted Sep 11, 2012
Israeli researchers believe that they have found a way to increase the survival and effectiveness of insulin-producing pancreatic cells transplanted into diabetic mice. The technique, developed by scientists at the Technion-Israel Institute of Technology in Haifa and Ben-Gurion University of the Negev in Beersheba, involves surrounding the transplanted beta cells with a three-dimensional latticework of nurturing blood vessels called "engineered tissue."
1 comment - Posted Sep 10, 2012
The media abounds with stories about the sudden collapse and death of athletes whom we assumed were in the best of health. When such cases occur, we may become concerned about exercising ourselves. A recent presentation describing people who had been exercising during or within one hour of a cardiac arrest may assuage these concerns to a degree.
1 comment - Posted Sep 7, 2012
Steve Richert, who has type 1 diabetes, has embarked upon a 365-day climbing mission to demonstrate that managing diabetes and rock climbing present similar challenges and to inspire people with diabetes to surmount those challenges. In this second part of our interview, I asked him about his motivations.
1 comment - Posted Sep 6, 2012
To a casual observer, Dr. Nat Strand might look like an over-achiever. After all, she and her partner won Season 17 of her favorite television show, "The Amazing Race." Winning the race opened her world up to the diabetes community, which, interestingly enough, inspired her to take better care of herself. Her mission now is to encourage everyone with diabetes to connect with the diabetes community and benefit from knowing others who understand the daily challenges of managing type 1 diabetes. When I caught up with Dr. Strand, we began by talking about what drove her to enter the Amazing Race.
2 comments - Posted Sep 5, 2012
The Mayo Clinic Health Letter for August 2012 has published three lifestyle changes that could stave off the progression of prediabetes to full-blown type 2 diabetes. The list isn't new, but its periodic reiteration indicates that healthcare researchers and providers have settled on a simple prescription for staying diabetes-free.
1 comment - Posted Sep 4, 2012
Steve Richert, who has type 1 diabetes, has embarked upon a 365-day climbing mission to demonstrate that managing diabetes and rock climbing present similar challenges and to inspire people with diabetes to surmount those challenges. When I caught up with Steve on a rare day when he happened to be at sea level, I asked him about his mission.
1 comment - Posted Sep 1, 2012
Older type 2s who exercise tight control over their blood sugar may run an increased risk of hip fracture, says a study from Changi General Hospital in Singapore. The researchers studied 558 elderly people with diabetes who had been treated for hip fracture between 2005 and 2010. They found that those patients had a significantly lower median A1C, 6.8%, than the control group median of 7.4%. In 59.2 percent of the hip fracture cases, the patient's A1C was less than 7%, and slightly more than three-quarters of the patients were taking sulfonylureas.
1 comment - Posted Aug 30, 2012
The Food and Drug Administration has approved US sale of generic pioglitazone (trade name Actos) for the treatment of type 2 diabetes. Actos, originally developed and trademarked by Takeda Pharmaceuticals, works by decreasing insulin resistance in type 2 patients. The prescription drug, which belongs to the class of drugs known as thiazolidinediones (TZDs), has enjoyed great commercial success in the United States since its introduction in 1999, posting estimated sales last year of $2.7 billion.
0 comments - Posted Aug 27, 2012
A 30-year study of life expectancy among people with type 1 diabetes showed a dramatic increase during the second half of the study, say researchers at the University of Pittsburgh. Type 1s diagnosed between 1965 and 1980 have a life expectancy of 68.8 years—15 years more than type 1s diagnosed between 1950 and 1964. In the same period, general life expectancy for US residents increased by less than one year.
8 comments - Posted Aug 24, 2012
Amy Powell, the first recipient of the Diabetes Health Pharmacist and American Association of Diabetes Educators (AADE) scholarship, was honored at the 2012 AADE conference in Indianapolis. As the winner, her conference fees and accommodation costs were paid, and she received a one-year AADE membership.
0 comments - Posted Aug 18, 2012
As diabetes climbs to epidemic levels in the United States, and finding adequate resources to fund future U.S. healthcare remains in question, the need for an already existing "boots on the ground" group that can address the disease is greater than ever.
0 comments - Posted Aug 15, 2012
Endocrinologist Robert Cuddihy, MD, joined Sanofi US over a year ago to be the company’s Vice President and Medical Diabetes Head in the United States. He is responsible for developing and executing the US strategy for Sanofi’s Diabetes Division, including pharmaceuticals, devices, and other technologies. He previously served as the medical director for several organizations, including the International Diabetes Center-Park Nicollet in Minnesota.
0 comments - Posted Aug 13, 2012
If you like cheese, there may be cause for celebration. According to a new study, eating cheese may lower your risk for type 2 diabetes
1 comment - Posted Aug 8, 2012
Physically fit men with type 2 diabetes and a heart condition known as left ventricular hypertrophy run a considerably lower risk of premature death than their diabetic peers who are not fit. That's the conclusion of a longitudinal study of 866 patients conducted by Veterans Affairs Medical Center and George Washington University, Washington, DC.
0 comments - Posted Aug 7, 2012
UC San Diego scientists have discovered a molecule involved in regulating the biological clock that could open a new path for treating type 2 diabetes. The molecule, dubbed KL001, controls a key protein, cryptochrome, that regulates the biological clock (circadian rhythm) in plants, animals, and humans. In doing so, cryptochrome indirectly affects the liver's production of glucose. KL001 can be manipulated to induce cryptochrome to slow the liver's glucose production, thus creating a possible new therapeutic approach to type 2 diabetes.
1 comment - Posted Aug 6, 2012
A study has found that taking curcumin extract, the main ingredient of the popular Indian spice turmeric, may help ward off type 2 in those with prediabetes.
0 comments - Posted Aug 4, 2012
Editor's Note: Portions of this report were taken from a press release from CVS-Caremark.
0 comments - Posted Jul 26, 2012
In a small study of 10 type 1 children under the age of seven years, closed-loop insulin delivery improved their nighttime glycemic control. The therapy, delivered at Children's Hospital Boston, used an algorithm-controlled pump and continuous glucose monitor to deliver insulin on an as-needed basis as the children slept.
2 comments - Posted Jul 23, 2012
Immediately starting intense therapy for newly diagnosed type 2s preserved their beta cell functioning for 3.5 years, according to a University of Texas Southwestern Medical Center study.
0 comments - Posted Jul 18, 2012
New York researchers have reported that obese patients with type 1 diabetes who do not respond well to insulin may be able to improve their blood sugar control by adding liraglutide to their therapy. Liraglutide (brand name Victoza) is an injectible GLP-1 analog* that was introduced to the US market in 2010 to treat people with type 2 diabetes.
0 comments - Posted Jul 14, 2012
Bariatric surgery, which alters or blocks portions of the digestive system, has produced long-term remission of diabetes symptoms in many type 2 patients. However, a small study of obese type 2 patients who underwent bariatric surgery shows that the longer they had diabetes, the greater the chances that their disease recurred after surgery. The retrospective study, conducted by Yessica Ramos, MD, at the Mayo Clinic Arizona, found that patients who had had diabetes for five years or longer were nearly four times as likely to experience a recurrence of the disease after the remission brought on by the surgery.
1 comment - Posted Jul 9, 2012
University of California researchers report that they have found a new class of drugs that could lead to a pain relief treatment for people who have diabetic neuropathy. The drugs, which were successfully tested on lab animals, are anti-inflammatory compounds that inhibit the action of an enzyme called soluble epoxide hydrolase. The enzyme is key to the transmission of pain sensations. Previous research has shown that inhibiting soluble epoxide hydrolase also lowers blood pressure and protects against kidney damage.
0 comments - Posted Jul 7, 2012
Diabetes affects nearly 25 million Americans, and that number is expected to grow substantially every year. It's the fifth leading cause of death in America, more than breast cancer and AIDs combined. And according to a report released last week from the Agency for Healthcare Research and Quality (AHRQ), it's a disease that’s costing Americans $83 billion a year in hospital fees — 23 percent of total hospital spending.
3 comments - Posted Jul 5, 2012
British scientists say that they have discovered a link between obstructive sleep apnea (OSA) and diabetic peripheral neuropathy. OSA is defined as having five or more events per hour of hypopnea (abnormally slow or shallow breathing). The researchers, from the University of Birmingham, UK, report that the association between the two conditions is strong despite other factors that could be used to explain the correlation. According to their findings, published in the American Journal of Respiratory and Critical Care Medicine, the severity of the neuropathy correlates with the degree of OSA.
1 comment - Posted Jul 4, 2012
Annie Snyder figured she'd be out of the pediatrician's office in 30 minutes, tops. Then she'd head home, tuck the medical permission for YMCA summer camp in her bag and finish packing.
1 comment - Posted Jul 2, 2012
Metformin is the aspirin of the diabetes world, an almost-wonder drug that proves itself again and again the longer it's around. This time, a new study shows that postmenopausal women with diabetes who have taken metformin for several years are 25 percent less likely to develop breast cancer than nondiabetic women.
0 comments - Posted Jul 1, 2012
A small Chinese study has reported that 15 of 28 young type 1 patients, aged 14 to 30 years, who underwent an experimental adult stem cell procedure were able to stay off insulin injections for an average of 18 months. Though not conclusive, the study highlights an interesting avenue of research that could eventually dramatically reduce insulin dependence among type 1s.
10 comments - Posted Jun 29, 2012
A Walgreens study during which pharmacists counseled patients about taking injectable diabetes medications improved the patients' adherence by 24 percent.
1 comment - Posted Jun 27, 2012
Several hopeful trends emerged from this year's ADA Scientific Sessions in Philadelphia, held June 8 through 12.
1 comment - Posted Jun 23, 2012
Medical devices aren't just any old pieces of technology. Lives depend upon them. For that reason, the government outlined a process decades ago by which manufacturers and importers were supposed to report malfunctions. But there was one problem: When malfunctions occurred, the manufacturers and importers did not admit it. According to the Food and Drug Administration, "A 1986 General Accounting Office (GAO) study showed that less than one percent of device problems occurring in hospitals are reported to FDA, and the more serious the problem with a device, the less likely it was to be reported."
0 comments - Posted Jun 22, 2012
I've had type 1 diabetes for nearly 14 years. I have fallen off the wagon a few times, battled diabulimia, survived numerous insulin shock comas and ketoacidosis episodes, and struggled with acceptance: I have my scars. Despite these mistakes, I've picked myself up countless times and have prevailed. I've persevered with a disease that doesn't take vacations for even a minute, and I've come out on top. I'm alive and healthy, with a full life and a child of my own.
7 comments - Posted Jun 21, 2012
SAN DIEGO - June 15, 2012 - Dexcom, the leader in continuous glucose monitoring, is proudly sponsoring the efforts of the Diabetes Formation Flight USA(DFFUSA.org) - three pilots with insulin-dependent diabetes using Dexcom's Seven Plus as part of their effort to set new transcontinental world speed records while raising funds for the Juvenile Diabetes Research Foundation (JDRF).
0 comments - Posted Jun 20, 2012
An Israeli biotech company's cell therapy, designed to treat hard-to-heal diabetic ulcers, is now in phase 3 testing in the United States.
0 comments - Posted Jun 19, 2012
Last year, I gave birth to my daughter and shared my pregnancy and birthing experiences with you. The pregnancy was a very difficult but extremely rewarding experience. A few months after our daughter was born, my husband and I discussed whether we'd have another child. On one hand, I went through several insulin shock comas, severe insulin resistance, and pre-eclampsia, ending in an emergency cesarean section. Because my first pregnancy was so tough, we weren't sure if we wanted to risk another one. On the other hand, if we did have two children, we wanted them to be very close in age so that they could bond well. We figured that if the two children were around fifteen months apart, then my daughter would be too young to feel any tension about having another baby in the house. We hoped they'd be close enough in age that they would always have one another as a companion.
3 comments - Posted Jun 18, 2012
As I celebrate my birthday this month, I also recognize the anniversary of my diabetes. If it were a person, it would be legally old enough to move out. Oh, how I wish it would! I was diagnosed at eighteen years old with type 1 diabetes, so this makes eighteen long years that the two of us have been living together. I have so many mixed emotions about it. On one hand, I feel stronger and more certain of my decisions with diabetes than ever before. On the other hand, I feel pretty depressed that it's been so long and that, no matter how I try to push away the thought, complications could be looming around the bend.
4 comments - Posted Jun 17, 2012
If you have type 1 diabetes, you probably know that you're in it for the long haul. No diet, nutrition, or exercise plan is getting you out of this one. Our only hope for a life without insulin injections is a cure. It's a wonderful idea, but I'm not holding my breath.
9 comments - Posted Jun 11, 2012
Here is a statistic to warm the heart-literally: The death rate from heart disease and stroke among American adults with diabetes dropped 40 percent from 1997 to 2006, according to the Centers for Disease Control in Atlanta. The overall mortality rate among people with diabetes dropped 23 percent.
1 comment - Posted Jun 9, 2012
The US Food and Drug Administration has approved the use of Novo Nordisk's Levemir basal insulin for type 1 children aged two to five years. The FDA decision makes Levemir (insulin detemir [rDNA origin]) the only basal insulin approved for use in this age group.
Levemir, introduced to the US market in 2006, was previously approved for older children and adults with type 1 diabetes, as well as insulin-using type 2s.
0 comments - Posted Jun 7, 2012
A short animated video narrated in a woman's reassuring tone provides a basic look at diabetes. The presentation touches on the science behind the condition and explains important terms, including "pancreas," "glucose," and "insulin." It stresses the importance of regular A1C checks and taking medication if needed, while pointing out the dangers associated with not staying on top of blood sugar levels.
0 comments - Posted Jun 5, 2012
Not long ago, celebrity chef Charles Mattocks, who was recently diagnosed with diabetes, came across the twitter account that I use to connect with the diabetes community. He called me and told me about his idea for making a documentary about diabetes and asked if I would like to participate. Charles saw the need for an up-close view of our disease that would be very supportive of the diabetes community. Having had type 1 diabetes for 12 years, I jumped at the opportunity to be a part of a film that focuses on the struggles of dealing with diabetes.
3 comments - Posted Jun 2, 2012
A compound found in excessive quantities in the glucose of people with diabetes may hold the key to successful treatment of neuropathic pain, says an international team of researchers.
The compound, methylglyoxal, attacks and modifies a protein, called Nav1.8, in nerve endings.
0 comments - Posted May 26, 2012
Warmer temperatures bring the opportunity to put on our walking shoes and step outside for our workouts. But if you, like me, have been walking for many years, you may find yourself bored with the same old routine. To avoid burnout, try these five ways to rev up your walk.
0 comments - Posted May 21, 2012
The slow backlash against low-fat, relatively high-carb diets as the ideal for everyone with type 2 diabetes has received a boost from a team of Swedish researchers at Linkoping University, about 100 miles southwest of Stockholm.
0 comments - Posted May 20, 2012
It seems that every few months, we hear about a new diet that, like all the others, promises to yield fast and tempting results. Is the raw food diet any different, and, if so, how?
0 comments - Posted May 19, 2012
Scientists meeting recently at the International Liver Congress in Barcelona, Spain, say that microbiota-tiny organisms specific to a part of the body-transplanted from healthy people to people at risk of diabetes or nonalcoholic fatty liver disease may prevent the later onset of those conditions. The procedure involves implanting small quantities of fecal matter from healthy donors into the colons of pre-diseased recipients.
0 comments - Posted May 18, 2012
Researchers in Taipei, Taiwan, report that they have identified the top three drugs for reducing A1C levels in type 2 diabetes: biphasic insulin, GLP-1 analogs, and basal insulin. They hedged a little on their endorsement of GLP-1 analogs, however, by saying that although they are not decisively better at controlling A1Cs than other oral diabetes drugs, they have the advantage of helping to reduce weight without adding to the danger of hypoglycemia.
0 comments - Posted May 16, 2012
A successful experiment on mice with type 1 diabetes, which involved "reprogramming" their immune systems to stop attacks on pancreatic beta cells, may point the way to an eventual cure for the disease in humans.
6 comments - Posted May 15, 2012
With tens of millions of American facing life with type 2 diabetes and many millions more at risk of the disease, scientists are scrambling to unravel novel treatments. The latest breakthrough could come from California's Salk Institute.
0 comments - Posted May 13, 2012
Feeling tired? Your lack of rest may be putting you at increased risk of obesity and type 2 diabetes. That's the conclusion of a new paper, published in The American Journal of Human Biology, that looked at evidence collected from numerous experimental and observational studies. The link was clear: People who got less than six hours of sleep a night were more likely to have a high body mass index (BMI) and be obese. The connection found in the study seems stronger for children and teenagers, which is especially worrisome given the skyrocketing rates of type 2 diabetes in young people.
0 comments - Posted May 10, 2012
As an orthopedic surgeon, I have many patients with diabetes who tell me, "I can't have surgery because I won't heal." That is certainly not the case, however. Diabetes does affect the small blood vessels and the function of immune cells when blood sugar is high, but with proper nutrition and blood sugar management, people with diabetes are very safe to undergo knee replacements, abdominal surgery, and many elective procedures.
0 comments - Posted Apr 28, 2012
My oldest nephew, James, has a double whammy to deal with. His aunt, yours truly, has type 1 diabetes, and so does his father. I was in the room when my sister had an ultrasound during her pregnancy with James, and I clearly remember the doctor asking her if anyone in her family had diabetes. We shared a look as she informed the doctor of my diabetes and her husband's diabetes. I know we also shared a silent prayer as the reality hit us that diabetes might be passed on to her children.
0 comments - Posted Apr 27, 2012
The US Food and Drug Administration has okayed US sales of Bayer HealthCare's CONTOUR® Next EZ blood glucose monitoring system. The new BGM, currently available in other countries as the CONTOUR XT, will be available in the US market this summer.
0 comments - Posted Apr 25, 2012
NeuroMetrix, Inc., a Massachusetts-based medical device company, has filed a 510(k) form with the US Food and Drug Administration for the SENSUSTM, a pain therapy device for people who suffer diabetic neuropathy. A 510(k) is a "premarket notification" of a company's intent to market a medical product. The FDA then tests the product and provides feedback to the manufacturer. Once the FDA clears the product, its maker can introduce it to the US market.
0 comments - Posted Apr 24, 2012
As we approach the summer season, our thoughts turn to barbecues, picnics, amusement parks, and road trips to the beach. It is a season of fun, but it can be hard for people with diabetes to enjoy the festivities and still maintain healthy eating habits.
1 comment - Posted Apr 23, 2012
Just a 1 percent weight loss in older people with type 2 diabetes can improve their physical mobility by up to 7 percent, according to a new study just published in the New England Journal of Medicine.
0 comments - Posted Apr 16, 2012
North Carolina-born chef Sam Talbot first came to national attention when he placed third in the Season 2 run of Bravo's Top Chef TV competition. Sam, who has type 1 diabetes and wears an insulin pump, held the executive chef position at several New York City restaurants, including Black Duck, Williamsburgh Cafe, and Punch, before opening his current restaurant, the acclaimed Surf Lodge, in Montauk on Long Island.
0 comments - Posted Apr 11, 2012
To discover the relationship between potassium levels and type 2 diabetes, a Johns Hopkins University study looked at more than 12,000 participants in the Atherosclerosis Risk in Communities Study (ARIC), performed in 1987 and 1996. The study found that as potassium levels went up, the incidence of diabetes among study participants went down. The more than 2,000 African Americans in the study had lower average potassium levels than the 9,000 Caucasians and were twice as likely to develop type 2 diabetes.
0 comments - Posted Apr 8, 2012
The FDA has approved the start of outpatient trials of a smart phone-based monitoring device that functions as an artificial pancreas. If the device, which automatically measures blood glucose levels and adjusts them with insulin, is successful, several million type 1 patients could enjoy a whole new level of convenience.
9 comments - Posted Mar 27, 2012
Long-term use of metformin as a weight loss aid is both safe and effective in preventing or delaying the onset of type 2 diabetes, says the Diabetes Prevention Program Research Group.
0 comments - Posted Mar 25, 2012
A little more than 25 years ago, I was diagnosed with type 1 diabetes.
3 comments - Posted Mar 21, 2012
Massachusetts researchers have found that even years after they are diagnosed with type 1 diabetes, some people continue to possess functioning beta cells. This finding departs from the conventional thinking that in type 1 diabetes beat cell activity inevitably ceases--the result of attacks on the cells by the body's immune system.
0 comments - Posted Mar 19, 2012
If you are newly diagnosed with type 2 diabetes and don't take insulin, a new study says that you are likely to have better A1Cs if you have access to blood glucose testing supplies and use them. The finding comes from a large Cochrane review of previous studies that took place in many countries.
0 comments - Posted Mar 17, 2012
Everyone needs vitamin D to be healthy and maintain strong bones, but a new study has found that it may also protect against stroke. In the study, 21,000 people aged 45 and older answered a food questionnaire. According to the findings, presented at the American Stroke Association's International Stroke Conference, there was an 11 percent reduction in stroke among those who consumed the most vitamin D.
0 comments - Posted Mar 16, 2012
There are more than 200 diabetes camps in North America, offering more than 400 programs to more than 30,000 youths and young adults with diabetes and their families. One in 400 children has type 1 diabetes, and type 2 diabetes in children, once rare, is increasingly common due to obesity. Education and motivation are vital to healthy management of the disease. Diabetes camps empower children and their families to meet the rigorous demands of diabetes, allowing them to be healthy, active, and motivated to reach their dreams.
0 comments - Posted Mar 15, 2012
According to a study of patients newly diagnosed with type 2 diabetes, 35 percent of the time their physicians did not follow the American Diabetes Association (ADA) guideline that calls for prescribing a generic drug first. The study, conducted by researchers from CVS Caremark, Harvard University, and Brigham and Women's Hospital, reviewed the pharmacy claims of 254,000 patients who were started on a diabetes medication in January 2006 and December 2008. One-third of the treatment regimens did not adhere to the ADA guideline.
0 comments - Posted Mar 13, 2012
One quarter of patients with diabetic neuropathy undergo unnecessary, expensive tests, according to a study by Brian Callaghan, MD, of the University of Michigan Medical School. When Dr. Callaghan and his team looked at 1996-2007 Medicare claims of patients diagnosed with peripheral neuropathy, they found that the most common test performed was an MRI of the brain or spine. There were far fewer instances of glucose tolerance tests. Other tests that were done, but much less often, included fasting glucose levels, A1Cs, vitamin B12 levels, and serum protein electrophoresis.
0 comments - Posted Mar 12, 2012
0 comments - Posted Mar 10, 2012
When it comes to diabetes, people often blame the patient instead of the disease. I cannot think of another chronic illness for which this is the case. Much of the public seems to believe that we bring diabetes on ourselves. When people with diabetes are diagnosed with complications, uninformed observers often insist that it happened because they were "bad diabetics." Comments like "She didn't take care of herself" make me instantly defensive and angry. How can anyone know what that person went through on a day-to-day basis with her diabetes?
11 comments - Posted Mar 8, 2012
For people with diabetes, elevated blood sugar adversely affects the ability to heal. Their slow-healing wounds invite hard-to-treat infections that can eventually lead to amputation. In fact, they are 15 times more likely to undergo limb amputations than people without diabetes.
2 comments - Posted Mar 7, 2012
Sometimes I feel like an idiot. It usually happens when I read a blog by one of my favorite "D" parents telling about how their children are handling life with type 1 diabetes. These brave kids put up with the same things that adults with diabetes do, and some are literally too young to even understand what's going on. Reading about these little warriors makes me regret even more the fact that I wallowed in self pity all afternoon just because my blood sugar didn't cooperate flawlessly during my daily walk.
1 comment - Posted Mar 6, 2012
The latest clinical guidelines for treating type 2 diabetes from the American College of Physicians (ACP) indicate that when diet, exercise, and weight loss fail to control blood sugar levels in early type 2 patients, physicians should prescribe metformin as the first drug therapy.
2 comments - Posted Mar 1, 2012
British researchers say that metformin, the drug most often used to treat prediabetes and type 2 diabetes, could provide potential protection against endometrial cancer in women.
0 comments - Posted Feb 24, 2012
As a woman with diabetes, you may have noticed that you face unique challenges, from where to place your insulin pump, to pregnancy, to hormone fluctuations. Many diabetes books offer general diabetes advice, but few focus on women beyond just a short chapter. That is, until now.
2 comments - Posted Feb 20, 2012
Up to seven years before she becomes pregnant, a woman's risk of developing diabetes during pregnancy can be identified based on routinely assessed measures of blood sugar and body weight, according to a Kaiser Permanente study published in the online issue of the American Journal of Obstetrics and Gynecology.
2 comments - Posted Feb 19, 2012
Try doing this at the age of 64:
0 comments - Posted Feb 18, 2012
You've heard of the blockbuster drug Byetta, a daily injection for type 2 diabetes? Byetta's sister product, Bydureon, which is injected just once a week, has just been approved by the FDA and is available in pharmacies.
15 comments - Posted Feb 17, 2012
There are lots of articles about diabetes, as well as all kinds of information about anemia. But what if you have both? About 25 percent of people with diabetes have some level of anemia. This article explains how the two conditions interact.
3 comments - Posted Feb 16, 2012
Using a log book can be cumbersome, but it has many benefits. Tracking your blood sugars allows you to spot trends and provides a landscape view of how your body reacts to changing circumstances. It’s crucial to understand your body’s responses to food, illness, stress, and simply over-indulging in festive activities. Keeping track of these variables helps you better manage your diabetes.
0 comments - Posted Feb 15, 2012
Wiped out and dejected, that's my state of mind this morning. I had a really low blood sugar, and it's left me feeling like I've been in a fight. My arms and legs feel heavy, and my "low" headache lingers, but I remind myself that it could be worse. I'm fine, I treated it, and my day will go on.
11 comments - Posted Feb 14, 2012
My son learned to crawl last month. As a part-time stay-at-home dad, I found it both exciting and terrifying. Through crawling, my son has entered a new stage in life. He might have rolled or scooted a few feet before, but now he can see something in another room and make up his mind to go there.
1 comment - Posted Feb 10, 2012
Researchers at the Centers for Disease Control and Prevention report that foot and leg amputations decreased dramatically between 1996 and 2008. Over those 12 years, amputations dropped from 11 out of every 1,000 diabetic adults to only four-a decrease of almost 64 percent. Over the same period, however, the number of people officially diagnosed with diabetes tripled.
0 comments - Posted Feb 9, 2012
Diabetes doesn't confine itself to a single week or month. It's a year-round condition, and each season offers its own challenges and opportunities for those of us with the disease. We should be prepared to change and evolve as the seasons shift--not only to stay healthy, but also to enjoy all the fun that our dynamic world offers.
1 comment - Posted Feb 7, 2012
Barley has more beta glucan fiber than any other grain, and it has repeatedly established positive clinical results with regard to diabetes control. It not only boosts immune function by supporting macrophages and neutrophils, lowers blood pressure and cholesterol levels, and helps control obesity, but also attenuates postprandial glucose levels, improves insulin sensitivity, and promotes a feeling of satiety.
6 comments - Posted Feb 5, 2012
After several years of delays and setbacks, Amylin Pharmaceuticals has received FDA approval to begin US marketing of BydureonTM. The first once-a-week type 2 therapy to be offered in the US market, Bydureon is expected to be available by February. Amylin says that its wholesale price will be about $4,200 a year.
2 comments - Posted Feb 3, 2012
Two years ago, I was a different woman. I was just beginning to come out of my diabetes shell, assessing my confidence with strangers by testing in public and telling friends about my disease. I can still feel the panic rising in my throat as I told people that I have diabetes and need to take injections multiple times per day. I was afraid of rejection, afraid that they would treat me like a sick person. But after eleven years of fighting for my life with type 1 diabetes, I was tired of being afraid. The more people I told, the easier it got.
7 comments - Posted Feb 1, 2012
Animas Corporation, a division of Johnson & Johnson that manufactures insulin pumps, has been reprimanded by the FDA for not reporting serious problems resulting from use of its equipment. The parent company was warned that it could face fines and more for selling faulty insulin pumps and failing to disclose serious injuries to diabetic patients who used the OneTouch Ping and 2020 insulin pumps. According to reports, J&J continued to sell the pumps even after the company knew that some had failed.
1 comment - Posted Jan 29, 2012
Until now, drawing blood has been an unavoidable component of being tested for prediabetes and diabetes. Nobody enjoys the process, and it probably makes many people shy away from undergoing diagnosis at all.
1 comment - Posted Jan 28, 2012
The FDA has given Roche the go-ahead to market its Accu-Chek® Nano SmartView blood glucose monitoring system. The Nano, which uses Accu-Chek SmartView test strips, will be available to US consumers within the first half of this year. It is part of the same product line as the Accu-Chek Aviva Nano and Accu-Chek Performa Nano systems, which Roche has already launched in several overseas markets.
3 comments - Posted Jan 22, 2012
A young man in his early thirties struggles through traffic on his small Honda motorbike. As he enjoys a short break at a traffic signal, one foot on the road, his eyes are attracted to a billboard picturing a succulent burger. While he gazes, fantasizing about lunch, his vision starts to blur.
3 comments - Posted Jan 21, 2012
I wake in the morning with the taste of sour milk on my tongue. I'm sweating, extremely weak and disoriented. My muscles ache at the thought of moving. I have a sick feeling in my stomach, and it's threatening to come up my throat. I'm not sure what day it is. Nausea hits in a wave, sending chills down my spine.
28 comments - Posted Jan 17, 2012
Ethan Lewis, diagnosed with type 1 diabetes at the age of 12, founded GlucoBrands only 11 years later. The company produces a portable, inexpensive, tasty, fast-acting glucose gel that people can take to quickly restore healthy blood sugar levels when they experience hypoglycemia.
1 comment - Posted Jan 16, 2012
LifeScan has introduced the OneTouch® VerioTM IQ, a meter that not only tracks and displays blood sugar patterns, but also announces them with messages, such as "Looks like your blood sugar has been running LOW around this time."
2 comments - Posted Jan 15, 2012
Australian scientists have discovered that when a complex sugar crucial to the survival of insulin-producing pancreatic beta cells is degraded by the body's immune system, the beta cells die.
0 comments - Posted Jan 14, 2012
Recently, there has been a great deal of discussion on the subject of testing your blood sugar and taking insulin shots in public. A shocking number of people on social networks have commented that their family members don't want them to test their blood sugar or take their shots in public. They report having to inject in restrooms or even through their clothing to avoid drawing attention or offending their families. One hypersensitive husband even objected when his recently diagnosed wife took a shot in the relative privacy of their car.
41 comments - Posted Jan 12, 2012
Professional snowboarder Sean Busby started competing at age 14 and began training for the Winter Olympics at 16. But in 2004, at age 19, Sean's troubling bouts of thirst and weariness were revealed as symptoms of type 1 diabetes.
1 comment - Posted Jan 10, 2012
A dietary supplement, also known as a food supplement or nutritional supplement, contains a "dietary ingredient" intended to supplement the diet by providing an element that might not otherwise be consumed. "Dietary ingredients" include vitamins, minerals, herbs and other botanicals, amino acids, and substances such as enzymes, organ tissues, and metabolites. Dietary supplements, which may be extracts or concentrates, come in many forms, including tablets, capsules, soft gels, gelcaps, liquids, powders, and bars.
0 comments - Posted Jan 7, 2012
Some women who drink two of more sugary beverages daily are lucky: their consumption of sweetened drinks doesn't put on extra weight.
1 comment - Posted Jan 5, 2012
Spring Health Solutions, Inc., has released an instructional video describing its Spring Universal Infusion Set, recently approved by the FDA and Health Canada. The video, at www.SpringUniversal.com, is designed to help consumers properly use the product.
0 comments - Posted Jan 4, 2012
Canadian researchers report that just 30 minutes of intense exercise per week can reduce blood sugar levels for up to 24 hours after each exercise session and help prevent post-prandial spikes in patients with type 2 diabetes.
0 comments - Posted Jan 3, 2012
What's it really like to have type 1 diabetes? Every morning I start the day with a finger prick and two insulin injections. It doesn't matter if I don't feel like it. It doesn't matter if I'm tired. There is simply no room for pre-coffee dosage errors, excuses, or whining. Some mornings are good and some are bad, based upon my blood glucose reading. Its level varies greatly depending on whether my liver has released large stores of glucose during the dawn hours.
25 comments - Posted Jan 1, 2012
Vaginal yeast infections are annoying, not dangerous, but they can seriously hamper your sex life, especially if you have diabetes. What's the connection, and what can you do to prevent and treat yeast infections?
3 comments - Posted Dec 29, 2011
Diagnosed with diabetes at age 15, Brandy Barnes went on to a successful career as a pharmaceuticals salesperson, but she deeply missed having other diabetic women in her life to whom she could relate. Finally, after a difficult pregnancy, long thought, and prayer, she founded DiabetesSisters (www.diabetes.sisters.org), a North Carolina-based nonprofit organization that provides education and support to women of all ages with all types of diabetes. DS offers conferences, websites, blogs, and a "sister match" program, all designed to lessen feelings of isolation and deepen bonds of connection among women with diabetes.
0 comments - Posted Dec 28, 2011
Editor' Note: This article continues Katherine Marple's series on pregnancy with diabetes as a complicating factor. For previous articles, enter her name in the search feature at the top right-hand of this website. The next installment, "Birthing Options," will appear on December 30.
1 comment - Posted Dec 27, 2011
Diabetic retinopathy is caused by damage to blood vessels of the retina. Almost everyone who has had diabetes for thirty years or more has some sign of the condition. Now, retinopathy researchers have come up with a device that will be implanted behind a patient's eye to deliver medication on demand. "We wanted to come up with a safe and effective way to help diabetic patients safeguard their sight," said lead author Mu Chiao, a mechanical engineering associate professor at the University of British Columbia (UBC) in Vancouver, in Science Daily. "This new device offers improvements upon existing implantable devices for drug delivery."
2 comments - Posted Dec 26, 2011
An article in an Indiana newspaper documents an alarming rise in diabetes among Arizona's Hispanics, especially along the US border with Mexico. The Republic, published in Columbus, Indiana, reports that 13.5 percent of residents in Arizona's Yuma County had diabetes in 2010. Almost 60 percent of the border county's nearly 200,000 residents are Hispanic.
0 comments - Posted Dec 24, 2011
Health experts are unanimous that obesity or being overweight are major factors in the onset of type 2 diabetes. So it's no surprise that researchers here and abroad are working to develop weight-loss drugs that can help people shed pounds and lessen their susceptibility to diabetes.
1 comment - Posted Dec 23, 2011
Diabetes Health readers who are Amanda Lamb fans can watch her first-ever Christmas single, "Christmas In Love," on YouTube.
0 comments - Posted Dec 22, 2011
We are a tight-knit community. I'm not talking about my neighbors in my hometown of Chicago. I'm talking about my worldwide neighbors in the diabetic online community. Anyone dealing with diabetes knows the bond that it brings. When a person with diabetes is wronged, the rest of us feel the sting. Most of us living with diabetes have stories about people badgering our diet choices, saying inappropriate or insensitive things, and, sadly, crossing the line even further.
5 comments - Posted Dec 20, 2011
On July 21, Claire Duncan was one of three people with type 1 diabetes on a six-person relay team that swam across the English Channel. The team, swimming to raise funds for the Juvenile Diabetes Research Foundation, covered the 22-mile route in 13.5 hours, starting from a beach between Folkestone and Dover in England and finishing in France near Cap Gris Nez, between Boulogne and Calais.
0 comments - Posted Dec 17, 2011
"I have type 2 diabetes, diagnosed five years ago, and am 67 years old. I have worked very hard to manage this disease, but without the success I would like."
0 comments - Posted Dec 16, 2011
Here's good news for people who love nuts and Greek yogurt! Replacing even one serving of red meat with these tasty foods can substantially lower your risk of type 2 diabetes, according to a new study from the Harvard School of Public Health.
1 comment - Posted Dec 11, 2011
Drug company Merck aims to give people with type 2 diabetes two treatments for the price of one. The new therapy, called Juvisync, was just approved by the US Food and Drug Administration. It's not a radical new treatment, but instead a helpful combination of two familiar standbys: Juvisync unites the active ingredients in blood sugar-lowering Januvia and cholesterol-lowering Zocor in a single tablet.
0 comments - Posted Dec 10, 2011
Many people with diabetes admit to keeping their diabetes a secret. Less than two years ago, I was one of them. I hated the way people treated me when they found out about my diabetes. I hated being told that I wasn't allowed to eat things by people who didn't have a clue about diabetes. I hated the horror stories people told about their acquaintances with diabetes. I hated people asking me if I had the "bad" kind of diabetes.
10 comments - Posted Dec 9, 2011
Will the federal government kill the artificial pancreas? The Juvenile Diabetes Research Foundation (JDRF) is raising the alarm over FDA guidelines that could stifle the technology necessary for the development of an artificial pancreas.
12 comments - Posted Dec 8, 2011
Women are better at coping with problems than men, right? Not when it comes to being diagnosed with type 2 diabetes. According to a new survey, that diagnosis had a greater negative impact on women's emotional outlook and adherence to diet and exercise than the same diagnosis given to men. The survey was conducted in September 2011, and included 831 completed responses from 458 women and 373 men.
1 comment - Posted Dec 6, 2011
Forensic scientist Mark Ruefenacht, who has type 1 diabetes, tells Diabetes Health publisher Nadia Al-Samarrie how he realized that dogs can be a major defense against life-threatening episodes of hypoglycemia. That insight led him to found Dogs for Diabetics ("D4D"), a Concord, California-based organization that trains dogs to alert their masters when they sense low blood sugar. D4D's website is located at www.dogs4diabetics.com/
3 comments - Posted Dec 4, 2011
This year's DREAM Award, presented by the Disability Rights Legal Center (DRLC), was given to Nick Jonas, the musician and actor best known as one of the three Jonas Brothers. He was among the special recipients at the DRLC's annual Franklin D. Roosevelt Dinner, held this year on November 17, 2011.
2 comments - Posted Dec 3, 2011
Jeff O'Connell is the author of "Sugar Nation: The Hidden Truth Behind America's Deadliest Habit and the Simple Way to Beat It." I discovered his book while browsing the shelves of my local library, and I could hardly put it down. Though I have type I diabetes and O'Connell's book focuses on type 2, I found many of his thoughts applicable to my own health. His book is no doubt controversial, so I wanted to delve deeper into his daring claims and share his responses with the diabetic community. After reading my interview with Jeff, please leave a comment below to let Diabetes Health know what you think.
10 comments - Posted Dec 2, 2011
Just take a look around. It's pretty clear that many of us are carrying more weight than we used to. Obesity has skyrocketed in recent years, and it's not about to stop. Roughly one in three adults is obese today, and researchers now predict that 164 million adults will be obese by 2030. That's half of all adults in the country.
0 comments - Posted Dec 1, 2011
People with diabetes may want to have their hearing checked, based on a study that found hearing problems twice as common among them as among people without diabetes.
0 comments - Posted Nov 19, 2011
Heather Shields was thrilled when she got the opportunity to dance with the famous Joffrey Ballet School in New York City. At 11 years old, she dreamed of one day becoming a professional ballerina, and this trip would bring her dream a little closer. A long way from home for this California girl, Heather traveled with her family to the "Big Apple" for the month of July. During that month she remembers dancing six to seven hours a day in the heat of the summer. She began losing weight, but shrugged it off, assuming she'd caught her mom's stomach bug.
0 comments - Posted Nov 17, 2011
When I was first diagnosed with type 1 diabetes, I recall the numerous comments that people blurted out in an attempt to make me feel better about my situation. But the truth was that I just needed to be treated like everyone else. I was in the midst of a confusing, depressing, and life-altering diagnosis. The last thing I needed was a pat on the back that felt more like a slap in the face.
11 comments - Posted Nov 15, 2011
Want a simple way to find out if you or someone you know is likely to develop type 2 diabetes? Just answer these three simple questions!
0 comments - Posted Nov 13, 2011
Final weeks of pregnancy! The third trimester brings about many more ultrasound scans and measurements taken to judge the growth and health of your child. You'll likely be visiting your OB/GYN or maternal fetal medicine office twice per week for non-stress tests to ensure that your baby is healthy and active.
4 comments - Posted Nov 9, 2011
The search for a cure for diabetes is a noble pursuit, but a cure always seems to be another ten years down the road. Finding a way to be healthy in the here and now is what matters for people with diabetes. In 2005, Peter Nerothin started Insulindependence (IN), a nonprofit organization that aims to "revolutionize diabetes management" by leading experiential diabetes education expeditions for type 1 youths.
0 comments - Posted Nov 8, 2011
Sometimes it feels like diabetes is driving you crazy. But what if the disease is actually changing your brain? That's the disturbing suggestion of a new study from the Washington University School of Medicine in St. Louis. The study suggests that both high and low blood sugars affect the brain development of young people with diabetes, but in different ways.
4 comments - Posted Nov 7, 2011
By now you're halfway through pregnancy. You've managed to get through the stresses of insulin shock in the first trimester and insulin resistance beginning in the second trimester, and you're well on your way toward your third trimester. Congratulations! A moment of applause, please.
1 comment - Posted Nov 2, 2011
When doctors hand out a diagnosis of diabetes, I wish they'd give you a list of tips that can make life happier living with the illness. After my diagnosis, I felt ashamed of my diabetes, ashamed of my inability to control it with diet and exercise even though I literally worked out every single day for nine months straight. I skipped nearly all carbohydrates and didn't eat meat at the time, so all I ate was nuts, cheese, eggs, and vegetables. The doctor didn't put me on insulin right away because I was eighteen, and she wasn't sure if I had type 1 or type 2. But nothing I did was working. It was soon apparent that I was type 1 and that insulin injections were unavoidable. I had no idea that it wasn't my fault. I felt hopeless, hungry, exhausted, and alone.
2 comments - Posted Nov 1, 2011
If you've had diabetes for a number of years, chances are that you remember when there was no Internet access and no diabetes online community. You had no way to look up information online and no instant connection to millions of others around the world living with diabetes. Unless you had a friend nearby with diabetes, there was no one to understand how you felt when your blood sugar numbers were less than stellar, and no one to sympathize with how hard it can be to get your A1C down.
3 comments - Posted Nov 1, 2011
The one time I needed a glucagon injection, I didn't have any. I had never been given a prescription for it, had no idea how to use it, and was absolutely clueless about what it did.
1 comment - Posted Oct 29, 2011
All blood tests are tools. Some are to diagnose diabetes, some are to help you manage your diabetes on a daily or long term basis and some are to keep you safe.
1 comment - Posted Oct 28, 2011
Technology now under development would allow people with diabetes to monitor their blood sugar through their contact lenses. Researcher Babak Parviz of the University of Washington in Seattle invented the lenses, which monitor the amount of glucose in tear fluid. That fluid tracks blood glucose levels closely, and Parviz hopes to have the lenses communicate wirelessly with some sort of auxiliary meter.
0 comments - Posted Oct 23, 2011
Trying to lose weight as an insulin-injecting person with type 1 diabetes couldn't be more frustrating. It gets on my last nerve that exercise can trigger mind-numbing lows, lows that cause me to inhale a portion of those recently burned calories. That said, I don't skip exercise to avoid lows. I just check my blood sugars more often, use caution with my insulin dosing, and follow the advice of my doctors.
22 comments - Posted Oct 21, 2011
I'm just going to come out and say it, the way people do in addiction meetings when they have hit "rock bottom." Hi, my name is Meagan. I was a very uncooperative diabetic for a great many years. I felt lonely, and I hated being different. I rarely checked my blood sugars. In fact, there were times where I didn't even know where my meter was.
12 comments - Posted Oct 17, 2011
Using stem cells that they extracted from the brains of diabetic lab rats, and turning them into insulin-producing pancreatic cells, Japanese scientists may be on the road to a virtual cure for diabetes that comes from people's own brains.
5 comments - Posted Oct 16, 2011
A brand new insulin will soon be on pharmacy shelves in the United States if Danish pharmaceutical company Novo Nordisk has its way. The company has filed for approval from the Food and Drug Administration to sell insulin degludec, an original formulation that lasts an extra-long time. Insulin degludec is injected only once a day. Once under the skin, the dose of insulin is absorbed slowly and consistently, allowing for better nighttime control, according to Novo. Most importantly, test subjects had a low rate of hypoglycemia on the drug.
2 comments - Posted Oct 15, 2011
My mother died unexpectedly this summer. While her loss was sad and sudden, I have many reasons to celebrate her life and the guidance she offered me. When I was diagnosed with diabetes as a child, she took it upon herself to learn the ins and outs of diabetes care. For most of the next decade, she oversaw my treatment.
6 comments - Posted Oct 6, 2011
What if we could stop the body's immune system from attacking the pancreas in the first stages of type 1 diabetes? What if we could keep the pancreas producing insulin, all the while helping it recover from the autoimmune barrage?
7 comments - Posted Sep 29, 2011
A couple of factors lead to increased risk of insulin shock comas during the first trimester. For many, insulin sensitivity increases and the pancreas isn't yet producing the hormones associated with insulin resistance. In addition, many type 1s will be taken off of their current basal insulin if it is not yet approved for use during pregnancy.
4 comments - Posted Sep 27, 2011
Imagine if there were a cure for diabetes that could be found inside your own body? Wouldn't it be nice if instead of depending on durable medical equipment, we could one day heal ourselves?
1 comment - Posted Sep 24, 2011
Scientists have found a protein that plays an important role in allowing our bodies to absorb glucose from our blood. What's more, lower levels of that protein may contribute to type 2 diabetes.
0 comments - Posted Sep 23, 2011
So, you're pregnant! Many who are in your shoes have worked very hard and diligently to begin this excursion. Others have reached this milestone unintentionally. Either way, you are about to embark on a journey that will completely challenge everything you know about your type 1 diabetes management. These next few months will challenge your motives, your emotions, your determination, and everything that makes up who you are. So sink your heels in. Take each step one at a time.
4 comments - Posted Sep 20, 2011
Scientists have found a protein that plays an important role in allowing our bodies to absorb glucose from our blood. What's more, lower levels of that protein may contribute to type 2 diabetes.
0 comments - Posted Sep 19, 2011
A recent report from the US Centers for Disease Control says that 12 states now have adult obesity rates of 30 percent or higher. Seven of those states are in the South. The CDC data are from the Behavior Risk Factor Surveillance System, a 2010 phone survey of 400,000 US adults. Obesity is defined as a body mass index of 30 or more.
0 comments - Posted Sep 15, 2011
I want to thank you all for the many comments that you have posted. As I said in the article, it does bother me that so many promises have been made and not kept regarding a cure. This has resulted in people just giving up hope and coming to believe that there will never be a cure for diabetes. Such promises are still being made today.
20 comments - Posted Sep 13, 2011
Will there be a cure for diabetes? Is an artificial pancreas a cure? Was insulin a cure? Let's begin on the correct platform. You may have an opinion on what a cure is that completely differs from mine, and that's okay.
45 comments - Posted Aug 24, 2011
Will there be a cure for diabetes? Is an artificial pancreas a cure? Was insulin a cure? Let's begin on the correct platform. You may have an opinion on what a cure is that completely differs from mine, and that's okay.
0 comments - Posted Aug 20, 2011
Low doses of metformin and rosiglitazone seem to delay the onset of type 2 in prediabetic people who have impaired glucose tolerance, according to a Canadian study. However, although the drug combination was effective over the first year of the study in helping to control glucose levels and insulin resistance, it was not effective subsequently in delaying the onset of insulin resistance and pancreatic beta cell deterioration.
0 comments - Posted Aug 7, 2011
Body fat is like two twins: one evil and one good. In this case, white fat-the kind that likes to cluster around the abdomen and hang on to calories-is the bad stuff. The "good" fat is brown, and it has been found to assist the body in burning calories, thus helping keep weight down.
0 comments - Posted Jul 15, 2011
Rensselaer Polytechnic Institute in upstate New York is working on a new approach to blood sugar monitoring that could open the door to an artificial pancreas. The plan is to develop an automated monitoring system so sophisticated that it can take into account the often great differences in blood sugar levels and insulin sensitivity among people with type 1 diabetes.
4 comments - Posted Jul 9, 2011
The Internet allows consumers to shop for deals on anything imaginable, even prescription drugs. The economic struggles that many currently face, paired with the increasing cost of healthcare and prescription drugs, have created an environment in which counterfeit drug makers can prosper.
1 comment - Posted Jul 7, 2011
Roger Hurdsman lives in Roy, Utah, surrounded by women. His wife of four years, Hilary, is there, along with his two young daughters, Bonnie and Tess. He seems to be handling the estrogen well though, perhaps because he devotes his days to designing software for the Department of Defense. He is able to spend time with computers and gadgets before being inundated with tea parties and dress-up when he gets home.
1 comment - Posted Jul 4, 2011
Say goodbye to the U.S. Department of Agriculture's old Food Pyramid. The tapered food guide is giving way to MyPlate, a colorful visual aid that shows the rough proportions of fruit, vegetables, protein, grains, and that dairy people should consume at every meal.
0 comments - Posted Jul 2, 2011
"Good news," my diabetes nurse educator says to me. "Your new insurance covers continuous glucose monitoring supplies!" I give her a half-smile as my brain screams at me, "CGM? Really? Something else to deal with on top of this damn disease, an insulin pump, exercise, and nutrition?" But I comply, and a CGM is added to the rest of my paraphernalia.
28 comments - Posted Jul 1, 2011
A new report shows that increasing numbers of consumers are using the Internet to track medical information that they can apply to their own health. The report, "The Social Life of Health Information," was issued by the Pew Research Center's Internet & American Life Project and the California HealthCare Foundation.
0 comments - Posted Jun 29, 2011
Lap-Band manufacturer Allergan has asked the U.S. Food and Drug Administration to allow surgeries using the device on overweight teenagers as young as 14 years old.
3 comments - Posted Jun 27, 2011
An Australian researcher who deliberately fed his lab rats a high-sugar/high-fat diet says that a flavonoid called rutin helped block the growth of fat cells in their abdomens and kept them from putting on weight despite their bad diet. Flavonoids are plant pigments that researchers are finding have beneficial metabolic effects because of their antioxidant capabilities.
0 comments - Posted Jun 21, 2011
Over the last decade, dramatic changes have occurred in our understanding of the onset and progression of prediabetes. Lightning speed changes have also occurred regarding the therapies available to achieve optimal blood glucose control. Even with all of this change, however, many old dogmas hang on. It's time to become aware of the new realities. In this article, I focus on two common old dogmas and the new realities.
2 comments - Posted Jun 16, 2011
Statistics from the 2011 Medco Drug Report show that diabetes drugs accounted for 16.1 percent of the overall increase in U.S. spending on therapeutic drugs in 2010. The report states that the increase is due to the growing number of Americans who have diabetes.
5 comments - Posted Jun 15, 2011
The U.S. Food and Drug Administration has said that starting on November 18, 2011, it will restrict retail pharmacy sales of three diabetes drugs manufactured by GlaxoSmithKline: the stand-alone Avandia (rosiglitazone) and the combination drugs Avandamet (rosiglitazone and metformin) and Avandaryl (rosiglitazone and glimepiride).
0 comments - Posted Jun 11, 2011
As prices rise, Americans are beginning to pay almost as much attention to the cost of food as they do to its taste. That's one of the findings of the 2011 Food & Health Survey, recently published by the International Food Industry Council Foundation (IFICF).
0 comments - Posted Jun 9, 2011
Amylin Pharmaceuticals has announced that it will collaborate with the Juvenile Diabetes Research Foundation to test a combination of Symlin and insulin in injectible form as a type 1 therapy.
0 comments - Posted Jun 3, 2011
A monitor attached to a mobile device helps people with type 2 diabetes lower their blood pressure more than simply having a blood pressure monitor available in the home. That's the conclusion of a year-long study conducted by the University Health Network in Toronto, Canada. The study showed that type 2 patients whose blood pressure was actively reported to their doctors via a Bluetooth-enabled device enjoyed lower blood pressure than patients whose readings were not passed on to doctors.
1 comment - Posted May 26, 2011
Meet the latest superfood: maple syrup. Wait a minute...maple syrup? The super-sugary stuff poured on pancakes and waffles and used to glaze hams? That maple syrup?
9 comments - Posted May 24, 2011
French drug maker Sanofi-aventis says that results from a Phase III trial of its experimental type 2 diabetes drug lixisenatide show that the drug successfully lowered patients' blood glucose levels and body weight, but did not increase the risk of hypoglycemia.
0 comments - Posted May 23, 2011
You're heard the doctors. You've read the articles. You know all about tight control.
25 comments - Posted May 20, 2011
New Jersey's Hackensack University Medical Center has announced that it will partner with Dr. Camillo Ricordi to test a surgical procedure that could hold the key to a cure for type 1 diabetes.
10 comments - Posted May 18, 2011
A study just published by VSP® Vision Care, a 56 million-member non-profit vision benefits and services company, reports that VSP has saved its clients $4.5 billion in potential healthcare expenditures via early detection of chronic eye diseases.
1 comment - Posted May 15, 2011
A Danish study of 107,806 adults taking various diabetes medications has found that three drugs are the most effective at lowering the risk of cardiovascular disease and death: metformin, gliclazide (not marketed in the US), and repaglinide (Prandin). Other common diabetes medications, including glimepiride, glibenclamide (glyburide), glipizide, and tolbutamide, were linked to a higher risk of death both from all causes and from heart attack and stroke.
1 comment - Posted May 13, 2011
A new study says that people who consume a "moderate" amount of candy per day have a slightly lower body mass index than people who don't eat candy. They also run a 15 percent lower risk than the general population of developing metabolic syndrome, the cluster of conditions that is often a precursor to type 2 diabetes.
1 comment - Posted May 11, 2011
HOLLYWOOD, FL -- They come from New York, Miami, Milwaukee and more. They have children of all ages with type 1 diabetes - and they're on a mission to find a cure. They're the "Real Moms of the DRI Foundation" and in honor of Mother's Day they're asking millions of moms - and others - to support the Diabetes Research Institute, a world leader in cure-focused research.
2 comments - Posted May 8, 2011
The drug discussed below is for the treatment of type 2 diabetes.
6 comments - Posted May 6, 2011
Recently, we published an article about the implantable pump "A Miracle Technology for Type 1s: Can It Be Saved?" Following the appearance of this article on the Diabetes Health website, over 100 readers commented, most of them expressing a heartfelt desire for access to this technology in the U.S.A. To read the original article click on link below:
A Miracle Technology for Type 1s: Can It Be Saved?
34 comments - Posted May 5, 2011
The rate of foot and leg amputations among people with diabetes fell by as much as 36 percent in one four-year period, according to a study of patients at Veterans Affairs clinics. Taking patients' age and sex into account, amputations-major and minor-dropped from about seven per 1,000 patients in 2000 to between four and five per 1,000 by 2004. The latter figure is a reduction of around 36 percent, with the biggest decrease coming in above-the-knee amputations.
0 comments - Posted May 4, 2011
Imagine knowing that you're likely to develop type 2 diabetes a decade from now. What would you do?
3 comments - Posted May 3, 2011
British researchers say that testosterone replacement therapy for type 2 men with low testosterone levels could reduce their death rate significantly. Over the course of a six-year study by the University of Sheffield, only 8.6 percent of low-testosterone subjects who were given replacement therapy died, compared to 20 percent of low-testosterone subjects who did not receive the therapy.
2 comments - Posted May 2, 2011
We all know by now that fat isn't necessarily a bad thing. Enough advertisements and recommendations for fish oil and omega-3 supplements have appeared over the past few years to make that clear. But what if "good fat" isn't just about eating fish or a taking a fishy-tasting supplement? What if that good fat can be found in a common cooking oil?
0 comments - Posted Apr 27, 2011
What is it about salt that brings out so many powerful flavors and strong feelings? Simple sodium chloride, or salt, as it's known to everyone but chemistry teachers, has been applied to food as a seasoning since the beginning of civilization. Unfortunately, the sodium in salt has proven dangerous both to diabetics and to healthy people who have a propensity toward heart disease.
1 comment - Posted Apr 26, 2011
Recently I had the pleasure of attending the Barbara Davis Center's "Management of Diabetes in Youth" conference, held every other year in beautiful Keystone, Colorado. The focus is on all of the latest and greatest in type 1, and it's a real treat to have so many of the best names in this field gathered in one place. The Barbara Davis Center (BDC) is one of the premier programs in the world focusing on type I diabetes management, and the one (Dr. Peter Chase, to be precise) who brought us the famed" Pink Panther" book, Understanding Diabetes - the reliable handbook of type 1 diabetes that many parents of newly diagnosed kids rely on.
3 comments - Posted Apr 25, 2011
Every year four million baby teeth fall out, and 1.4 million wisdom teeth are pulled out of our collective mouth. Until recently, the only entity really interested in all those teeth was the tooth fairy. But all that changed in the year 2000, with the discovery that dental pulp contains adult stem cells. In the not-too-distant future, those stem cells might be used for growing new islet cells to cure diabetes. The problem is, how to keep the teeth nice and fresh until that hoped-for day. That's where Provia Laboratories comes in, with their Store-A-Tooth service.
1 comment - Posted Apr 24, 2011
The National Institutes of Health has awarded a $1.15 million grant to a researcher at Eastern Virginia Medical School to investigate a protein that may prevent obese people from developing type 2 diabetes.
0 comments - Posted Apr 22, 2011
Phil Southerland's autobiography is an inspirational coming-of-age memoir about a type 1 baby who wasn't supposed to live. But his doctor's dismal prediction didn't take into consideration his mother's indefatigable determination that her baby would thrive no matter what, and Phil's own fierce drive to conquer every single challenge he encountered, including his diabetes. It's an engrossing book, a sports adventure story with a medical subplot and a roster of dynamic characters, the most dynamic of whom is Phil himself. If we could harness his energy, our dependence on foreign oil would be a thing of the past.
2 comments - Posted Apr 20, 2011
A new study has proven that use of a blood glucose meter with advanced features, when paired with diabetes education, more effectively manages blood glucose than using a basic feature meter. This information was presented at the recent 46th European Association for the Study of Diabetes (EASD) Annual Meeting in Stockholm, Sweden.
4 comments - Posted Apr 18, 2011
What if there were a technology that could make people with type 1 diabetes feel absolutely wonderful, completely healthy, better than they ever realized was possible? And what if it were about to disappear? Well, there is such a technology, and it is in serious jeopardy. It's called the implantable insulin pump, currently made by Medtronic. This is the story of four people who have been using this device for 20 years, and their desperate crusade to keep it from disappearing forever.
116 comments - Posted Apr 17, 2011
Researchers at the U.S. National Institute of Environmental Health have found that people with diabetes have a significantly increased risk of developing Parkinson's disease. Despite that finding, they say that there are too few data to support a causative link between diabetes and Parkinson's.
0 comments - Posted Apr 16, 2011
Greetings from Philadelphia International Airport! Airports are fascinating places...great for seeing what people look like and how they act under unusual circumstances. At this moment, I see a lot of truly overweight people. Most folks are treating the moving walkway like a ride at Disney World–just standing there, inching slowly along and staring blankly at the passing drywall. I don’t know…maybe the two sights are related. Have we really become this lazy? Have we “convenienced” our way out of being in shape? Have electronic toilet flushers, soap dispensers, and water faucets taken away our last opportunity to burn any calories at all?
0 comments - Posted Apr 14, 2011
If you have pre-diabetes and live in any of the five boroughs of New York City, get ready to learn a new acronym: YDPP. The initials stand for YMCA Diabetes Prevention Program, a public-private partnership under which New Yorkers can get enroll in a comprehensive low-cost diabetes prevention program at one of the city's 27 YMCA branches and affiliates.
2 comments - Posted Apr 12, 2011
Italian and Greek researchers conducting a meta-analysis* of the diets of more than 500,000 people have concluded that the Mediterranean diet reduces the risk of metabolic syndrome, a cluster of risk factors that are common precursors to type 2 diabetes. Those factors include overweight or obesity, a sedentary lifestyle, high blood sugar, high triglyceride levels, high blood pressure, and high "bad" cholesterol.
The Mediterranean diet is high in fruit, vegetables, whole grain foods, and low-fat dairy products. Proteins include fish, legumes, poultry, tree nuts, and mono-unsaturated fatty acids from olive oil. Alcohol intake is moderate and almost always in conjunction with meals. Red meat is only an occasional menu item.
The scientists looked at 50 studies that involved more than 500,000 people, then extrapolated the effects of a Mediterranean diet from them. Although the meta-analysis pointed to the usefulness of the Mediterranean diet in fending off metabolic syndrome, its authors said that their conclusion is tentative, given the need for more research on the topic.
The study was published in the March 15 issue of the Journal of the American College of Cardiology.
* A meta-analysis looks at a number of similar studies and tries to derive new and useful results from them by detecting common patterns among them.
0 comments - Posted Apr 12, 2011
After comparing results from 24 studies, researchers at the Chinese University of Hong Kong found little evidence that increasing soy intake improves people's blood sugar levels.
0 comments - Posted Apr 11, 2011
Taiwanese researchers say that a technology that uses sound waves to stimulate healing in diabetic foot ulcers is almost three times more effective than conventional hyperbaric oxygen therapy (HBOT). The technology, called dermaPACE®, is manufactured by SANUWAVE Health Inc., a medical device company located in Alpharetta, Ga.
0 comments - Posted Apr 10, 2011
An Enid, Oklahoma, billionaire and his wife have pledged another $20 million on top of the $10.5 million they had previously contributed to his namesake diabetes center at the University of Oklahoma.
3 comments - Posted Apr 9, 2011
Beta blockers, which many people with diabetes take to control high blood pressure, may be one of the reasons why type 2s often tend to gain and keep weight. That's the conclusion of a study from St. Vincent's Hospital in Sydney, Australia.
0 comments - Posted Apr 8, 2011
While smoking is commonly associated with a higher risk of developing a serious disease, it's not often that second-hand smoke or being an ex-smoker is considered even riskier. If the disease is type 2 diabetes, however, it is.
0 comments - Posted Apr 5, 2011
The Second Annual Native American Healthcare Conference will take place May 23 through 24 at the Treasure Island Hotel and Casino in Las Vegas. The conference will be held in conjunction with the Native American Diabetes Workshop at the same site.
1 comment - Posted Apr 4, 2011
As we wrote back in 2008, the EndoBarrier is a very clever way to simulate the effect of a gastric bypass without the unpleasant scalpel part. It looks like a long clear plastic stocking, and it's simply threaded through the patient's mouth and stomach, down to the small intestine, where it lines the intestine's upper section (the same part that is bypassed in traditional surgery). Food slips right through it, but digestive enzymes are trapped on its other side. The two don't get to join forces until a couple of feet further downstream, so the effect on diabetes is a lot like that of a bypass: It resolves the symptoms of type 2 diabetes.
0 comments - Posted Apr 1, 2011
This List defines terms that people with prediabetes commonly encounter as they learn more about the condition.
2 comments - Posted Mar 29, 2011
Researchers at the University of California at Davis have begun a study to see if patients' own adult stem cells can be used to increase lower leg blood circulation and possibly prevent amputation due to arterial disease or diabetes.
0 comments - Posted Mar 27, 2011
A New York University research team has won a pilot grant to see if blood from dental procedures could be used in conjunction with the A1C test to detect diabetes or pre-diabetes. The A1C test, which is becoming healthcare providers' preferred test for detecting the disease, typically uses blood extracted from finger pricks to make its analysis. The NYU team will see if the blood that flows from gum tissue during dental work can be used for the same purpose.
5 comments - Posted Mar 26, 2011
Now that a few months have passed since the New Year, what is the state of your resolution to lose weight? If it is a just a painful memory, you might be pondering the strength of your willpower and concluding that it is shamefully weak. In fact, it's not, according to Daniel Akst, the author of We Have Met the Enemy: Self-Control in an Age of Excess. Although a full two-thirds of us are overweight, our willpower is no weaker than that of the slim generations that preceded us. It's just that we're up against temptations that we never evolved to resist, in an environment that seduces rather than sustains us.
4 comments - Posted Mar 24, 2011
The U.S. Food and Drug Administration has accepted an application to review dapagliflozin, a drug for the treatment of type 2 diabetes that is being developed by Bristol-Myers Squibb and AstraZeneca.
0 comments - Posted Mar 22, 2011
Evolution works in strange ways. What serves as an advantage at one point in time can sometimes prove a problem later, when the world has changed. It looks like that might be the case with type 2 diabetes, according to researchers from San Diego, California.
2 comments - Posted Mar 21, 2011
The Centers for Disease Control and Prevention (CDC) has identified a swath of the southern U.S. as the country's "diabetes belt." In this region, made up of parts of 15 states, some 12 percent of the population has type 2 diabetes, compared with 8.5 percent of people in the rest of the country.
0 comments - Posted Mar 19, 2011
If a prisoner on death row wants to donate his organs, should he be allowed to do it?
21 comments - Posted Mar 18, 2011
Weight loss can help people with type 2 diabetes control their blood sugar and avoid potential health risks associated with the disease. Did you know that losing even seven percent of your body weight can lower blood sugar, reduce blood pressure, and improve cholesterol levels1?
"Consider diabetes as a disease that has different phases--with the central feature a disorder of insulin production and insulin use," said Roberta Anding, MS, RD/LD,CSSD,CDE. Anding is a clinical dietitian and certified diabetes educator at Baylor College of Medicine, as well as a national spokesperson for the American Dietetic Association. "To better control and lose weight safely with type 2 diabetes, it is important to consider the type and amount of food on your plate."
4 comments - Posted Mar 12, 2011
A new report recently published in the American Chemical Society's bi-weekly Journal of Agricultural and Food Chemistry adds a new punch to the power of garlic in the fight against heart disease. The report concludes that garlic has "significant" potential for preventing cardiomyopathy, a form of heart disease that is a leading cause of death in people with diabetes.
0 comments - Posted Mar 5, 2011
Novo Nordisk, the world's largest insulin manufacturer, has joined the Diabetes Prevention and Control Alliance (DPCA), a group whose goals are to reduce people's risk of developing diabetes and to work with people who already have it.
1 comment - Posted Mar 4, 2011
New University of Georgia research has found that a statin drug that is often known by the brand-name Lipitor may help prevent blindness in people with diabetes. In a study using diabetic rats, lead author Azza El-Remessy, assistant professor in the University of Georgia College of Pharmacy, and her colleagues found that statins prevent free radicals in the retina from killing nerves important to maintaining vision. The results of the study are published in the March edition of the journal Diabetologia.
0 comments - Posted Feb 23, 2011
In order to undergo gastric bypass surgery, you must have a BMI of at least 35. If you have type 2 diabetes and would like to undergo the surgery to alleviate your diabetes symptoms, you are out of luck unless you are also morbidly obese. A few less weighty type 2 patients have taken matters into their own hands by deliberately gaining enough weight to qualify, but now there is a less drastic way to qualify for the operation.
0 comments - Posted Feb 23, 2011
Folks who need that morning cup of coffee to get going may be protecting themselves from type 2 diabetes, a new study suggests. UCLA researchers wrote in the journal Diabetes last month that drinking four cups of coffee a day reduced women's chance of developing type 2 by a bit less than half. What's more, the scientists point to a specific reason why all that java has a beneficial effect: a protein known as sex hormone-binding globulin (SHBG). Scientists have suspected for some time that SHBG was connected to diabetes development.
0 comments - Posted Feb 19, 2011
Can't make insulin? That might not be a problem, according to Dr. Roger Unger, the lead researcher on a mouse study out of UT Southwestern Medical Center. As Dr. Unger stated in a press release, his findings "suggest that if there is no glucagon, it doesn't matter if you don't have insulin....In adulthood, at least with respect to glucose metabolism, the role of insulin is to control glucagon. And if you don't have glucagon, then you don't need insulin...If diabetes is defined as restoration of glucose homeostasis to normal, then this treatment can perhaps be considered very close to a ‘cure.' "
1 comment - Posted Feb 16, 2011
The final patient has performed the last visit of the main study period in Diamyd Medical's European Phase III study. Treatment with the antigen based therapy Diamyd® is made to investigate whether beta cell function and thereby blood sugar control can be preserved in children and adolescents with new onset type 1 diabetes. The top line results from this study are expected to be reported as planned, in late spring 2011.
0 comments - Posted Feb 15, 2011
A new analysis from Johns Hopkins University shows that women with diabetes are 50 percent more likely to die if they have breast cancer. Why? The challenges of diabetes management play a role, as well as women's overall health.
0 comments - Posted Feb 14, 2011
Many tragic complications of diabetes, including amputations, heart attack, stroke, and blindness, are due to blood vessel damage. According to Xiaochao Wei, PhD, of the Washington University School of Medicine in St. Louis, all that vascular damage may be caused by a shortage of one enzyme: fatty acid synthase, or FAS.
0 comments - Posted Feb 11, 2011
It's hard enough to be pregnant, but pregnancy with diabetes is especially challenging because it's so difficult to keep blood sugar within a normal range at a time when hormones are surging. All women try their best with the tools that they have, but even so, about half of all babies born to mothers with type 1 diabetes are overweight or obese at birth because of too much sugar in their mothers' blood. Mothers with high blood glucose levels also increase their child's risk of congenital malformation, stillbirth, neonatal death, preterm delivery, and neonatal admission.
0 comments - Posted Feb 9, 2011
In a new book, "Overdiagnosed: Making People Sick in the Pursuit of Health," Dartmouth researchers and physicians H. Gilbert Welch, Lisa Schwartz and Steven Woloshin argue that the medical establishment's embrace of early diagnosis and treatment as the key to keeping people healthy actually does the opposite.
0 comments - Posted Feb 8, 2011
It's generally thought that a genetic predisposition to type 1 diabetes is not enough to develop the disease, but that an environmental trigger is required to activate it. Researchers are not sure what that environmental trigger is, but enteroviruses have been under suspicion for quite a while. Enteroviruses are the second leading cause of viral colds in children.
1 comment - Posted Feb 8, 2011
A new study published in the journal Clinical Cardiology reveals that a Super Bowl loss for a home team was associated with increased death rates in both men and women and in older individuals.
0 comments - Posted Feb 4, 2011
INDIANAPOLIS and NEW YORK - Eli Lilly and Company and the Juvenile Diabetes Research Foundation (JDRF) today announced that they have signed an agreement to fund early-stage research that could enable patients with type 1 diabetes to regenerate insulin-producing cells destroyed by the disease.
0 comments - Posted Feb 4, 2011
The MOLLY and LINDSEY Diabetes Research Foundation at Hackensack University Medical Center (HUMC) and the Diabetes Research Institute (DRI), a Center of Excellence at the University of Miami Miller School of Medicine, have joined forces to find the cure for Type 1 Diabetes. Together they will form the Hackensack-Miami DRI Federation Project, a think tank of East Coast specialists who will fast-track the best research ideas coming out of the labs and put them to the test in clinically meaningful ways, thus shortening the path to a cure for those with type 1 diabetes.
5 comments - Posted Jan 26, 2011
Your young primary care doctor may not know a lot about diabetes, according to a study led by Stephen Sisson, MD, of the Johns Hopkins School of Medicine. "When I graduated from residency here, I knew much more about how to ventilate a patient on a machine than how to control somebody's blood sugar, and that's a problem," said Sisson in a press release. "The average resident doesn't know what the goal for normal fasting blood sugar should be. If you don't know what it has to be, how are you going to guide your diabetes management with patients?"
2 comments - Posted Jan 26, 2011
The kuriously named Kombiglyze XR, a combination of Onglyza (saxagliptin) and the old reliable metformin, has arrived at pharmacies and is available by prescription to people with type 2 diabetes. It's similar to Janumet, an older medication that's a combination of Januvia (sitagliptin) and metformin.
0 comments - Posted Jan 25, 2011
Keeping the lights on all night might keep away the monsters under the bed, but it also keeps away the "hormone of darkness," melatonin, according to a new study in the Journal of Clinical Endocrinology and Metabolism. Melatonin, which is secreted into the blood by the brain's pineal gland at night, is involved in the circadian rhythm. Scientists believe that disrupting circadian rhythms can contribute to metabolic disease. Specifically, melatonin receptor genes have been linked to type 2 diabetes. Melatonin is also a powerful antioxidant that may help prevent cancer.
3 comments - Posted Jan 19, 2011
On the outskirts of Quito, the capital of Ecuador, meals are likely to be based on white rice, potatoes, sugar, and white bread. Given their reliance on high carbohydrate foods that are low in essential nutrients, many of the residents are overweight and malnourished at the same time. The lack of vitamin C in their diet may contribute to metabolic syndrome, according to researchers from the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University and the Corporacion Ecuatoriana de Biotecnologia. The researchers also concluded that vitamin E may have a protective effect against metabolic syndrome.
0 comments - Posted Jan 18, 2011
Brown fat is an entirely different animal than the white fat that we pack onto our hips to store excess calories. Instead of storing energy, brown fat actually burns glucose to produce heat (thermogenesis). It's brown because it contains special mitochondria that produce heat from the glucose when activated by cold. Adults don't have much of it, unfortunately, just a few grams if we're lucky. If we had about 50 grams and were cold enough to activate it, it would actually burn about 500 calories a day.
0 comments - Posted Jan 14, 2011
Taking your medicine can lead to quite a windfall in reduced medical claims, according to a study recently published in Health Affairs. Over the course of a year, patients with diabetes who took their medications as directed saved their insurance companies a handsome $3,756 compared to people who didn't, even after claiming as much as $1000 for those very medications. The money was saved because the patients spent less time at the emergency room and in the hospital, a nice benefit in itself.
1 comment - Posted Jan 11, 2011
Sitagliptin (Januvia) has long been used to reduce blood sugar in people with type 2 diabetes, but a new study indicates that it can do the same for those with type 1 diabetes. Sitagliptin is a DPP-4 inhibitor; that is, it inhibits, or temporarily prevents, the enzyme DPP-4 from destroying a helpful hormone called GLP-1. GLP-1, which is released by the gut when food arrives there from the stomach, lowers blood sugar by causing the release of insulin, reducing the secretion of glucagon, and slowing stomach emptying and nutrient absorption.
3 comments - Posted Jan 7, 2011
My trip began as I flew from Dallas to my home town of Philadelphia and then caught an early Amtrak train to New York City. Growing up in the Philadelphia area had given me an appreciation for U.S. history, but today I was going to learn something new: the history of diabetes. My daughter, Sarah, was diagnosed with type 1 diabetes in 2003, yet I didn't know much about the history of the disease. Living every day with the stress and worry that many parents have, I felt I had no time to spend learning how we got to the modern treatments we have today. I had focused only on doing my job as caregiver and supporter of my daughter. I was looking forward to learning something new.
10 comments - Posted Jan 3, 2011
A new study finds that combining the newer diabetes drug exenatide with insulin provides better blood sugar control in patients with type 2 diabetes than insulin alone and helps promote weight loss.
1 comment - Posted Dec 27, 2010
For those trying to eat a healthy diet, whole-fat dairy and trans fats are usually not on the menu - at least, not yet. Scientists have narrowed in on a trans fat component found mainly in dairy fat that may ward off type 2 diabetes and protect cardiovascular health. While the research is far from conclusive and requires much further study, it suggests fats may play a more complex role in human health than previously thought.
2 comments - Posted Dec 24, 2010
Being diagnosed with type 2 diabetes means a lot of change in your daily life. From blood glucose monitoring to watching what you eat to losing weight, it's hard to keep track of the changes you need to make to keep diabetes under control. One aspect of diabetes care that sometimes falls through the cracks is oral health care, which, if ignored, can lead to serious health complications.
2 comments - Posted Dec 22, 2010
ABU DHABI, United Arab Emirates-- One in three United Arab Emirates (UAE) residents could have diabetes or prediabetes by the end of the decade, according to a new analysis from international health and well-being company UnitedHealth Group, released at the World Health Care Congress Middle East meeting in Abu Dhabi.
0 comments - Posted Dec 17, 2010
A 10-year study by Harvard University scientists found that diabetes puts people at risk for depression and that depression puts people at risk for type 2 diabetes. The two-way connection between the diseases was discovered in 55,000 nurses surveyed over the decade.
1 comment - Posted Dec 17, 2010
Women who experienced sexual or physical abuse in childhood and adolescence-whether moderate or severe-run a higher risk of type 2 diabetes than women who were not abused, according to results from a study recently reported online in the American Journal of Preventive Medicine.
1 comment - Posted Dec 16, 2010
With nearly 16 million Americans living today with pre-diabetes, a condition that is the precursor to type 2 diabetes, and half of all Americans expected to have some form of diabetes by the year 2020, healthy eating is more important than ever (1,2). But here is some good news: a recent scientific study shows that incorporating almonds into your diet can help treat and possibly prevent type 2 diabetes, as well as cardiovascular disease.
0 comments - Posted Dec 15, 2010
(Reuters) - Stem cells can be transformed into the pancreatic cells needed to treat diabetes and into complex layers of intestinal tissue, scientists demonstrated in two experiments reported on Sunday.
6 comments - Posted Dec 13, 2010
"Congress passed a multi-year renewal of the Special Diabetes Program (SDP), ensuring that studies on promising diabetes treatments and avenues toward a cure continue uninterrupted. As the father of a son living with type 1 diabetes, and as CEO of JDRF, one of the leading advocates for the renewal of this program, I applaud the U.S. government for its continued commitment to end this disease.
2 comments - Posted Dec 13, 2010
Obese lab rats that have undergone gastric bypass surgery to induce weight loss show a reduced desire for sugar water compared to obese rats that have not had the operation. Researchers at Penn State College of Medicine who observed that outcome also reported that the rats' preferences for salty, sour, or bitter tastes did not change. Lean rats who were given gastric bypass surgery as a control showed no changes in any of their taste preferences.
0 comments - Posted Dec 11, 2010
0 comments - Posted Dec 7, 2010
If you have a new infant in your family and a family history of type 1 diabetes, feeding your baby a special formula when weaning off breastfeeding may protect against the development of the antibodies associated with type 1 diabetes, thus potentially shielding your child from developing the disease itself. This is the finding of a new study, conducted by Finnish researchers, that was published in the November 11 issue of the New England Journal of Medicine.
4 comments - Posted Dec 4, 2010
Celebrate the season with an eCard and help support the Diabetes Research Institute! Send your family, friends or business colleagues A Gift of Love...A Gift of Hope. They will feel special knowing you are supporting research to find a cure for diabetes.
0 comments - Posted Dec 3, 2010
A new drug for type 2 diabetes started showing up in drugstores this week, according to manufacturer Santarus. The FDA-approved drug, called Cycloset, takes an distinctive -- and not well understood -- approach to reducing blood sugar levels. The pill apparently works by increasing dopamine activity in the hypothalamus, a part of the brain. Dopamine is a brain chemical that plays a big role in people's behavior, mood, and ability to sleep. Scientists theorize that glucose intolerance and insulin resistance may in part result from abnormal activity of this chemical, and that upping dopamine activity may iron out these problems.That's the theory, at least: the drug's exact workings aren't known. But it seems to do the trick.
0 comments - Posted Nov 24, 2010
Hundreds of people like you are choosing to Be Part of Cure. They are sharing their personal experiences - both heartbreaking and inspiring - of how diabetes has touched their lives.
0 comments - Posted Nov 13, 2010
WASHINGTON, D.C., Nov. 10, 2010 --- Diabetes experts at a meeting convened by the U.S. Food and Drug Administration (FDA) and the National Institutes of Health (NIH) took the next step in advancing efforts toward the development of an artificial pancreas: putting forth clinical recommendations to ensure the safe and effective testing of artificial pancreas technology in real-life situations. We are pleased at today's meeting there was a strong consensus among leading clinicians, researchers and industry leaders regarding the path toward outpatient studies for both low-glucose suspend and artificial pancreas systems.
5 comments - Posted Nov 10, 2010
In a proof-of-concept study presented at the 2010 Annual Clinical Congress of the American College of Surgeons, the researchers note that the matrix not only helps to understand the micro-architecture of the pancreas, but also prolongs the survival and preserves the function of the islets. Islets survived longer in the bio-artificial matrix than in conventional transplantation sites, and they produced significantly more insulin when challenged with glucose.
0 comments - Posted Oct 30, 2010
Getting enough magnesium in your diet could help prevent type 2 diabetes. Dr. Ka He of the University of North Carolina at Chapel Hill and colleagues have found that people who consumed the most magnesium from foods and vitamin supplements were about half as likely to develop diabetes over the next 20 years as people who took in the least magnesium.
0 comments - Posted Oct 22, 2010
Reducing the cost of low-carbohydrate foods for people with diabetes could significantly reduce medical costs associated with the disease that affects more than 23 million Americans, according to a recent study.
0 comments - Posted Oct 20, 2010
European researchers have reported that when they transplanted fecal matter from healthy thin people into obese people with pre-diabetes, the latter group's insulin sensitivity notably increased. (Insulin sensitivity is the body's ability to properly use the insulin hormone to regulate the amount of glucose in the bloodstream. Pre-diabetes exists when increasing resistance to insulin creates higher-than-normal blood sugar levels, a precondition to the onset of full-blown type 2 diabetes.)
1 comment - Posted Oct 19, 2010
A meta-analysis* of 87 studies involving 951,083 patients, performed by a Canadian research team, shows that the pre-diabetic condition known as metabolic syndrome increases the risk of heart disease or stroke in patients by a factor of more than two.
0 comments - Posted Oct 17, 2010
University of Michigan scientists have identified events inside insulin-producing pancreatic cells that set the stage for a neonatal form of non-autoimmune type 1 diabetes, and may play a role in type 2 diabetes as well. The results point to a potential target for drugs to protect normally functioning proteins essential for producing insulin.
0 comments - Posted Oct 15, 2010
Cutting back on sleep reduces the benefits of dieting, according to a study published Oct. 5 in the Annals of Internal Medicine.
0 comments - Posted Oct 10, 2010
A national epidemiologic study finds a strong, consistent correlation between adult diabetes and particulate air pollution that persists after adjustment for other risk factors like obesity and ethnicity, report researchers from Children's Hospital Boston. The relationship was seen even at exposure levels below the current EPA safety limit.
0 comments - Posted Oct 1, 2010
Recognising Diabetes as the Global Epidemic of the 21st century and looking at the high prevalence of debilitating diabetes in the region, the First International Diabetes Summit will be Hosted in United Arab Emirates in Dubai on the 8th and 9th of October with the support from the GCC Health Ministers Council and The Council of Nursing and Nursing Specialization for Cooperation Council States.
0 comments - Posted Sep 28, 2010
Diabetes research is on the cusp of new advances in treatment options and in understanding the underlying causes of both type 1 and type 2 diabetes. Among those are potential treatments using stem cells to regenerate a patient's ability to produce insulin, as well as upcoming clinical trials of a vaccine that potentially could prevent type 1 diabetes.
2 comments - Posted Sep 27, 2010
The U.S. Food and Drug Administration today announced that it will significantly restrict the use of the diabetes drug Avandia (rosiglitazone) to patients with Type 2 diabetes who cannot control their diabetes on other medications. These new restrictions are in response to data that suggest an elevated risk of cardiovascular events, such as heart attack and stroke, in patients treated with Avandia.
0 comments - Posted Sep 23, 2010
For the first time, scientists have found that blood levels of some ribonucleic acids (microRNAs) are different among people with type 2 diabetes and those who subsequently develop the disease compared to healthy controls, according to research reported in Circulation Research: Journal of the American Heart Association.
0 comments - Posted Sep 22, 2010
Children who have a high risk of developing type 2 diabetes might be identified earlier by way of tell-tale genetic indicators known as biomarkers. Some of those new biomarkers might be pinpointed in research led by Nancy F. Butte and funded by the U.S. Department of Agriculture (USDA) and the U.S. Department of Health and Human Service's National Institutes of Health.
0 comments - Posted Sep 22, 2010
The presence of amyloid protein may produce a chain reaction which destroys vital insulin-producing cells. Researchers based in Dublin, writing in the journal Nature Immunology, say future drugs could target this process. Amyloid is implicated in many other diseases - most notably Alzheimer's.
0 comments - Posted Sep 17, 2010
The JDRF is celebrating its 40th anniversary this year. A lot has changed in the past four decades. One change has to do with the organization's name. JDRF stands for Juvenile Diabetes Research Foundation. Years ago we called what we now know as type 1 diabetes, Juvenile Onset Diabetes Mellitus (JODM). We called it that because we knew (or thought we knew) it was the kind of diabetes that occurred in children. We now know that type 1 diabetes occurs in people of all age groups. There was a lot we didn't know 40 years ago, one of which was that type 1 diabetes is an autoimmune disease.
0 comments - Posted Sep 16, 2010
In type 1 diabetes, the body relentlessly attacks and destroys its own insulin-producing pancreatic beta cells. But a study by Joslin Diabetes Center scientists now has firmly established that some of these cells endure for many decades in a small group of people with the disease-offering clues to potential treatments for preserving and even restoring the crucial cell population.
0 comments - Posted Sep 14, 2010
The exact cause of type 1 diabetes is still unknown, but international researchers have found a link between the blood sugar disorder and a network of immune system genes.
0 comments - Posted Sep 13, 2010
Long-term weight loss may release into the blood industrial pollutants linked to illnesses like diabetes, hypertension and rheumatoid arthritis, researchers said on Tuesday. These compounds are normally stored in fatty tissues, but when fat breaks down during weight loss, they get into the blood stream, said lead researcher Duk-Hee Lee at the Kyungpook National University in Daegu in South Korea.
0 comments - Posted Sep 8, 2010
Type 2 diabetes and Alzheimer's disease are two distressing, but increasingly common, diseases seen in our aging population. At some point in the future, they may well overwhelm the healthcare system.
0 comments - Posted Sep 5, 2010
The Holy Grail pursued by all diabetes researchers is a complete cure for both the type 1 and type 2 forms of the disease. But until then, the "artificial pancreas," a combination of glucose monitoring and insulin dosing technology, may be as close as they get to a final breakthrough in treating diabetes.
0 comments - Posted Sep 3, 2010
Results of brain surgery on a small group of type 2 diabetes patients point the way to a possible new approach for treating the disease.
0 comments - Posted Sep 1, 2010
MannKind Corporation announced that the company will supply its novel, ultra rapid acting insulin AFREZZATM (insulin human [rDNA origin]) for use in a study being conducted by the Juvenile Diabetes Research Foundation (JDRF) as part of its Artificial Pancreas Project. The planned two-year study in patients with type 1 diabetes will leverage the unique rapid action of AFREZZA for use in a closed-loop blood sugar monitoring and insulin delivery system, termed the "artificial pancreas" by the JDRF. The study will be managed in conjunction with the Sansum Diabetes Research Institute and the University of California, Santa Barbara.
0 comments - Posted Aug 29, 2010
Doctors have long known that different populations have different risks for chronic illness. Certain ethnic groups, for instance, are more likely to develop type 2 diabetes than others. But why? The National Institutes of Health aims to find out. It's Network on Inequality, Complexity, and Health will take a broad look at factors that influence disease and aim to make positive changes.
0 comments - Posted Aug 25, 2010
PPARy is a protein that regulates the body's production of fat cells. However, obesity can modify how PPARy works, leading to decreased insulin sensitivity and the development of metabolic syndrome. (Metabolic syndrome is the cluster of factors, including insulin resistance, overweight, high blood pressure, and abnormal blood sugar levels, that is a precursor to type 2 diabetes.)
0 comments - Posted Aug 22, 2010
Gene variants associated with an increased risk for type-1 diabetes and rheumatoid arthritis may confer previously unknown benefits to their human carriers, say researchers at the Stanford University School of Medicine. As a result, the human race may have been evolving in the recent past to be more susceptible, rather than less, to some complex diseases, they conclude.
0 comments - Posted Aug 21, 2010
(Reuters) - Genetic testing might have helped identify people who would become depressed or suicidal while taking Sanofi-Aventis' weight loss drug Acomplia, which might have helped keep the drug on the market, U.S. researchers said on Thursday.
0 comments - Posted Aug 19, 2010
"The objective of this clinical trial (research study) is to determine if the medications can rescue the few beta cells that remain soon after the diagnosis of type 1 diabetes; and whether new beta cells can even be regenerated," commented Alex Rabinovitch, MD, Principal Investigator of the trial and Associate Director of The Sanford Project. "The investigational combinations of these medications could possibly allow patients to decrease or no longer need to inject insulin to keep their blood levels under proper control."
0 comments - Posted Aug 12, 2010
And wouldn't it be great if that pill weren't something advertised on late-night TV, but rather a legitimate treatment? A drug called rimonabant, introduced in Europe, seemed to fit the bill at first, but it was pulled from the market in late 2008 due to concerns about psychiatric side effects.
0 comments - Posted Aug 10, 2010
The Healthcare Leadership Council (HLC) - a coalition of chief executives representing all sectors of American healthcare - announced the formation of the National Dialogue for Healthcare Innovation (NDHI), a forum in which leaders from private sector healthcare, government, academia and patient and consumer organizations can work toward consensus on the most important issues affecting healthcare innovation.
0 comments - Posted Aug 6, 2010
Novo Nordisk presented results demonstrating that once-daily Victoza® (liraglutide [rDNA] injection) achieved significantly greater improvements in blood sugar control compared to placebo among African-American patients with type 2 diabetes. The meta-analysis of phase 3 data from the Liraglutide Effect and Action in Diabetes (LEAD) trials were presented at the 2010 National Medical Association Annual Convention & Scientific Assembly.
0 comments - Posted Aug 5, 2010
NEW YORK, NY, July 26, 2010 - Recalling the desperate fight for life that used to be waged by juvenile diabetes patients, and commemorating the events of 1921 that inaugurated a new era of hope for them and their families, the New York Historical Society will present the exhibition Breakthrough: The Dramatic Story of the Discovery of Insulin from October 5, 2010 through January 31, 2011. Exploring the roles of science, government, higher education and industry in developing and distributing a life-saving drug, the exhibition will bring to life the personalities who discovered insulin and raced to bring it to the world and will tell the story of one extraordinary New York girl-Elizabeth Evans Hughes, daughter of the leading statesman and jurist Charles Evans Hughes-who was among the very first patients to be saved.
0 comments - Posted Jul 26, 2010
A long-term study on the safety of a popular diabetes drug was put on hold Wednesday by the Food and Drug Administration, while the FDA considers whether it's too dangerous to continue. Several large studies have linked the drug, Avandia, to a higher risk of heart attacks and other heart problems. While other studies have not found the same risk, last week an FDA advisory panel recommended that the drug not be sold without a stronger warning label or possibly limits on who could receive it.
0 comments - Posted Jul 23, 2010
We have known for several years that Hepatitis C, a common cause of liver cirrhosis and cancer, also makes people three to four times more likely to develop Type 2 diabetes. In studying the insulin resistance of 29 people with Hepatitis C, Australian researchers have confirmed that they have high insulin resistance, a precursor to diabetes. However, almost all insulin resistance occurs in muscle, with little or none in the liver, a very surprising finding given that Hepatitis C is a liver disease.
0 comments - Posted Jul 21, 2010
From environmentally friendly hybrid cars and heating with solar power to organic or natural foods, our culture is increasingly embracing green strategies. "Using natural dietary supplements to support healthy blood sugar levels and minimize the impact of glycation is a rational continuation of this green philosophy," says Steven Joyal, MD, vice president of Scientific Affairs and Medical Development for the Life Extension Foundation in Ft. Lauderdale, Florida (www.lef.org). He is also author of the book What Your Doctor May Not Tell You About Diabetes.
1 comment - Posted Jul 20, 2010
(Reuters) - The first new prescription weight-loss pill in more than a decade failed to win backing from U.S.health advisers, who said safety concerns about the drug outweighed its ability to help obese patients shed pounds.
0 comments - Posted Jul 19, 2010
While teetotaling is the surest way to avoid abusing alcohol, it turns out that moderate alcohol intake may be one way to stave off the development of type 2 diabetes.
0 comments - Posted Jul 16, 2010
The U.S. Food and Drug Administration's (FDA) Joint Meeting of the Endocrinologic and Metabolic Drugs Advisory Committee and Drug Safety and Risk Management Advisory Committee has completed their evaluation of the scientific research available on the safety of rosiglitazone. The deliberations of the panel reflected the complexity of the issues, with several members voting to add additional warnings or to withdraw the drug from the U.S. market. Ultimately, the final recommendation was to allow Avandia to remain on the market. Now that the expert panel has concluded its meeting, the FDA will review their recommendations and make the final decision on whether the drug remains available to patients.
0 comments - Posted Jul 15, 2010
Having discovered a dramatic increase of an easy-to-detect enzyme in the red blood cells of people with diabetes and pre-diabetes, Johns Hopkins scientists say the discovery could lead to a simple, routine test for detecting the subtle onset of the disease, before symptoms or complications occur and in time to reverse its course.
0 comments - Posted Jul 15, 2010
A massive study involving 485 people with type 1 diabetes at 30 locations across North America shows that the combination of an insulin pump and a continuous glucose monitor helps patients achieve significantly lower A1c levels than multiple daily insulin injections.
0 comments - Posted Jul 13, 2010
Data from the massive ACCORD study on intensive blood sugar control shows that lowering blood sugar levels in people with longstanding type 2 diabetes to near-normal may delay the appearance of signs that point to damage to nerves, eyes, and kidneys, but does not stop their progression toward it.
0 comments - Posted Jul 9, 2010
A study released in late June has brought some welcome news to the makers of Byetta and Januvia: Users of the two diabetes drugs run no greater risk of developing pancreatitis than people with diabetes who take other drugs. In fact, both drugs seem to put users at slightly less risk for the condition.
0 comments - Posted Jul 8, 2010
A clinical trial that used testosterone gel, a topically applied ointment, to increase muscle strength in older men with low testosterone levels was stopped because adverse cardiovascular events increased significantly among patients receiving the treatment.
0 comments - Posted Jul 7, 2010
AFREZZA TM (insulin human [rDNA origin]) Inhalation Powder, a well-tolerated, investigational ultra rapid acting mealtime insulin, as part of a diabetes treatment regimen, provides long-term glucose control comparable to usual insulin therapy but with a significantly reduced incidence of hypoglycemia and less weight gain in patients with Type 2 diabetes, according to a two-year study presented at the American Diabetes Association's 70th Scientific Sessions.
0 comments - Posted Jul 6, 2010
In a recent study of the relationship between vitamin D deficiency and glucose intolerance in people with type 2 diabetes, more than 90 percent of the type 2 diabetes patients were found to be deficient in vitamin D, with their control over the disease worsening as their deficiency increased.
0 comments - Posted Jul 4, 2010
In people with longstanding type 2 diabetes who are at high risk for heart attack and stroke, lowering blood sugar to near-normal levels did not delay the combined risk of diabetic damage to kidneys, eyes, or nerves, but did delay several other signs of diabetic damage, a study has found. The intensive glucose treatment was compared with standard glucose control.
0 comments - Posted Jul 2, 2010
Depomed, Inc. and Santarus, Inc. announced new data suggesting that patients previously intolerant of metformin may be able to tolerate higher doses of metformin when treated with GLUMETZA® (metformin HCl extended release tablets). The finding will be presented at the 70th Scientific Sessions of the American Diabetes Association (ADA) in Orlando. GLUMETZA is a once-daily, extended release formulation of metformin, and is approved for use in adults with type 2 diabetes mellitus. It is promoted in the U.S. by Santarus.
0 comments - Posted Jul 1, 2010
A malfunction in the pancreas's "circadian clock*," the built-in timer found in all living things that regulates major biological processes, may be one of the reasons that people develop diabetes.
0 comments - Posted Jun 29, 2010
White rice and brown rice are reminiscent of those old dramas about identical twins, wherein one turns out to be angelic and the other turns out to be bad news.
0 comments - Posted Jun 28, 2010
City of Hope researchers have found that bone marrow transplantation with islet cell transplantation shows promise as a treatment for late-stage type 1 diabetes. This combination may enable patients to make their own insulin again. Results from laboratory research led by Defu Zeng, MD, associate professor in the departments of Diabetes Research and Hematology & Hematopoietic Cell Transplantation at City of Hope, were published online this month in the journal Diabetes.
0 comments - Posted Jun 25, 2010
Researchers from the National Jewish Health and University of Colorado Anschutz Medical Campus have found a specific protein fragment, or peptide, that stimulates an immune system attack resulting in diabetes. Their experiments in mice contradict conventional wisdom about such peptides and support work by scientists studying autoimmune diseases.
0 comments - Posted Jun 24, 2010
The American Diabetes Association and the American Cancer Society have issued a joint consensus statement that acknowledges some links between diabetes and cancer but also notes there are numerous questions that have yet to be answered.
0 comments - Posted Jun 23, 2010
IMIDIA ("Innovative Medicines Initiative for Diabetes"), a public private consortium funded by the Innovative Medicines Initiative (IMI), announced today the launch of a project focusing on pancreatic islet cell function and survival. Academia, biotech and pharma industry have joined forces to develop biomarkers and tools to pave the way for improved disease management and ultimately provide a cure for diabetes.
0 comments - Posted Jun 18, 2010
One of the factors that increases the risk of acquiring type 2 diabetes is excess body fat. So it makes sense that losing weight has always been one of the first lines of defense against the disease. Yet people who are slender -skinny, even- sometimes develop type 2. Why is that? Does the fact that a slender person can acquire type 2 negate the need for weight control?
0 comments - Posted Jun 18, 2010
Italian researchers have found a link between a common virus and type 1 diabetes that may open the door to answers about what triggers the disease in children.
0 comments - Posted Jun 17, 2010
A Duke University Medical Center study has concluded that obese men who have type 2 diabetes are almost four times as likely to be diagnosed with high-grade prostate cancer during a prostate biopsy as men who do not have diabetes. When ethnicity is taken into account, obese white men run a five-times greater chance of being diagnosed with high-grade prostate cancer.
0 comments - Posted Jun 15, 2010
A Canadian study that tracked 207 patients suggests that a low-dose combination of metformin and Avandia can reduce the development of type 2 diabetes by 66 percent in people at high risk for the condition.
0 comments - Posted Jun 15, 2010
Diabetic ketoacidosis poses enough of a threat on its own. But in a small number of cases, it leaves sufferers open to a potentially fatal infection called mucormycosis.
0 comments - Posted Jun 12, 2010
New guidelines from the American Diabetes Association and two other major medical associations advise not prescribing low-dose aspirin therapy for women under 60 or men under 50 who have diabetes but no other risks for heart disease.
0 comments - Posted Jun 12, 2010
WASHINGTON - In collaboration with Blue Cross and Blue Shield companies, the Blue Cross and Blue Shield Association (BCBSA) launched the Good Health ClubSM Physician Toolkit - unique educational materials designed to foster better communication between pediatricians and their patients on childhood obesity and diabetes prevention. The toolkit will be available to pediatricians in communities across the country.
0 comments - Posted Jun 11, 2010
We all know that certain chemicals in everyday products are harmful: mercury and lead, just to name a couple. But how harmful, and what can we do about it?
0 comments - Posted Jun 9, 2010
Results from a Phase 3 study demonstrate MACUGEN® (pegaptanib sodium) significantly improved vision in patients with diabetic macular edema (DME), a complication of diabetes that is a leading cause of blindness in people of working age.¹ In the study, 37 percent of patients treated with MACUGEN gained two lines, or 10 letters, of vision on the ETDRS eye chart at 54 weeks, compared to 20 percent of patients who received a sham (placebo-like) procedure which consists of anesthesia and a simulated injection in the eye (p=0.0047). The data were presented at the World Ophthalmology Congress in Berlin by Frank G. Holz, an investigator in the trial and director of the University Eye Hospital at the University of Bonn in Germany.
0 comments - Posted Jun 7, 2010
If you take metformin to control your type 2 diabetes, ask your doctor to take a look at your vitamin B-12 levels when you get a chance. A recent British study shows that metformin may cause a deficiency in the vitamin, which is necessary for the regeneration of red blood cells and the maintenance of nervous system health.
0 comments - Posted Jun 5, 2010
Dr. Rutai Hui of the Chinese Academy of Medical Sciences and Peking Union Medical College in Beijing and colleagues found chocolate only helped people who already had risk factors for heart disease and only when consumed in modest amounts.
0 comments - Posted Jun 4, 2010
The United States Department of Health and Human Services released The National Action Plan to Improve Health Literacy aimed at making health information and services easier to understand and use. The plan calls for improving the jargon-filled language, dense writing, and complex explanations that often fill patient handouts, medical forms, health web sites, and recommendations to the public.
0 comments - Posted May 30, 2010
Both genetic components and environmental factors play a role in most chronic diseases, including type 2 diabetes. In the same way that researchers use a Genome-Wide Association Study (GWAS) to evaluate the role of genetic factors in disease, scientists at Stanford University have used an Environmental-Wide Association Study (EWAS) to evaluate environmental factors on diabetes.
0 comments - Posted May 29, 2010
As awareness of pre-diabetes grows, the list of conditions that can lead to it seems to be growing. Along with obesity and a sedentary lifestyle, researchers may start listing lack of sleep as another danger signal. Two recently published studies conclude that sleep deprivation can lead to insulin resistance-a precursor for diabetes-and even increase the risk of early death.
0 comments - Posted May 26, 2010
A Seattle-based study has found that people with diabetes run a 40 percent increased risk of developing a common type of abnormal heart rhythm known as atrial fibrillation*. The study also shows that as people with diabetes take drugs for the disease, their risk for developing atrial fibrillation increases three percent for each year that they use such medications.
0 comments - Posted May 25, 2010
A new contest, "Give Back. Simply Win." sponsored by Bayer Diabetes Care will shine a spotlight on people with diabetes who are making a difference in their local communities. Three grand prize winners will meet international singing sensation Nick Jonas and Bayer will donate $5,000 to three not-for-profit charitable causes, one selected by each winner.
0 comments - Posted May 24, 2010
Grammy-award-nominated teen pop sensations the Jonas Brothers helped raise more than $250,000 at the annual "Rock For Diabetes" benefit on May 16, held at the home of Danny DeVito and Rhea Perlman. More than 200 people attended this year's benefit, which raised funds for the Center for Endocrinology, Diabetes and Metabolism at Children's Hospital Los Angeles.
0 comments - Posted May 22, 2010
Tattoos aren't just an art form or a way of making a personal statement anymore: They are beginning to save lives.
1 comment - Posted May 20, 2010
A husband-and-wife research team at the UC Davis School of Medicine has been awarded a five-year, $3.3 million grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development to lead the first prospective, nationwide, multi-site clinical study of how to prevent the neurological injuries and, in rare cases, death caused by brain swelling in children in diabetic crisis.
0 comments - Posted May 19, 2010
On Tuesday, Pathway Genomics announced that their personal genetic testing kit (InsightTM Saliva Collection Kit) would soon be available at the pharmacy chain Walgreens. The next day, the FDA released a letter it had sent to Pathway Genomics on Monday saying hold on, there was no approval on record for Pathway's Genetic Health Report. By Thursday, Wallgreens announced that it was delaying the sale of the genetic testing kits.
0 comments - Posted May 15, 2010
Most people who have diabetes quickly learn that one of the worst side effects of the disease is pain caused by damage to the hands and feet. High blood sugar inflames nerves, leading to tingling and numbness, and often, severe pain. Researchers at the Comprehensive Pain Center at Oregon Health & Science University in Portland have learned that onset of nerve pain may have a daily rhythm, with the worst occurring late at night around 11 p.m. Their study, which they characterized as "preliminary," tracked 647 people with diabetic neuropathy. The results showed that the typical pattern for people with the condition was to experience the greatest pain from it after sunset, peaking at 8 p.m. and 11 p.m.
1 comment - Posted May 14, 2010
Over 80 years ago, famed diabetologist Elliot Joslin said about the treatment of patients with type 1 diabetes: "Ketoacidosis may kill a patient, but frequent hypoglycemic reactions will ruin him." Unfortunately, hypoglycemia continues to be the most difficult problem facing most patients, families, and caregivers who deal with the management of type 1 diabetes on a daily basis. Frequent hypoglycemia episodes not only can "ruin," or adversely impact the quality of life for patients, but also, when severe, can cause seizures, coma, and even death.
13 comments - Posted May 13, 2010
Dr. Richard Hays announced today that he is now recruiting children with newly diagnosed type 1 diabetes for Protégé Encore, a randomized, placebo-controlled Phase III clinical trial. This is the second of two Phase III studies testing the safety and efficacy of an investigational drug called teplizumab. The first study, known as Protégé, has completed enrollment of more than 530 subjects with type 1 diabetes. There is currently no approved therapy to slow the progression of type 1 diabetes.
0 comments - Posted May 12, 2010
Scientists at the Mayo Clinic have developed a molecule that can block the breakdown of insulin. Their discovery could lead to development of a new class of drugs to help treat diabetes.
0 comments - Posted May 10, 2010
Most women with gestational diabetes know that taking steps to manage the disease during pregnancy is critical for the health of both mother and child. What many women don't realize is that those steps need to continue even after the baby is born.
0 comments - Posted May 7, 2010
Osiris Therapeutics announced that it has been granted Orphan Drug designation from the U.S. Food and Drug Administration (FDA) for Prochymal as a treatment for type 1 diabetes mellitus. The FDA instituted the Orphan Drug Act to promote the development of treatments for underserved patient populations. To be eligible for Orphan Drug designation, the treatment must target a disease that affects fewer than 200,000 new patients per year in the United States.
0 comments - Posted May 7, 2010
A new study to be published in the June issue of the Journal of Clinical Endocrinology & Metabolism (JCEM) says that a single night of too little sleep can induce insulin resistance.
2 comments - Posted May 6, 2010
CINCINNATI - The popular diabetes medication metformin works in different fashion than the current widely accepted view. This new finding could lead to wider use of the drug-particularly in people with cancer.
1 comment - Posted May 4, 2010
A Danish analysis of data from 21 research studies on the effects of saturated fat intake has concluded that swapping refined carbohydrates, such as pasta and white bread, for fat causes spikes in blood sugar that are harmful to the heart. However, cutting down on saturated fats while increasing consumption of whole-grain breads and vegetables-low glycemic index* foods-had a discernible positive impact on heart health.
0 comments - Posted May 2, 2010
Clinical studies at 52 different sites nationwide have shown that combining standard laser treatments with injections of the drug ranibizumab (Lucentis) offers substantially better results for treating macular edema than laser treatments alone. The research showed that almost 50 percent of patients treated with the combination therapy showed substantial improvement in their vision after one year, compared with 28 percent of patients who had been treated solely with laser.
1 comment - Posted May 1, 2010
NEW YORK, April 27, 2010 - The Juvenile Diabetes Research Foundation announced today that it is partnering with Living Cell Technologies (LCT), a New Zealand-based biotechnology company focused on developing cell based therapeutics, in a Phase II clinical trial to study the safety and effectiveness of transplanting encapsulated insulin-producing cells from pigs as a treatment for type 1 diabetes with significant hypoglycemia unawareness.
1 comment - Posted Apr 28, 2010
A team of researchers from Case Western University published an article revealing their invention of a "smart" insulin molecule that binds considerably less to cancer receptors and self-assembles under the skin. To provide a slow-release form of insulin, the compound self-assembles under the skin by "stapling" itself together with zinc ions. Zinc staples connect the pieces of the insulin puzzle together to create a functional protein.
0 comments - Posted Apr 23, 2010
The study, published in the journal Diabetes Care, adds to evidence that metformin, a generically available drug commonly used for type 2 diabetes, may have anti-cancer effects.
0 comments - Posted Apr 22, 2010
Researchers at Loyola University have discovered a group of immune system cells called natural killer T (NKT) cells that slow the wound healing process. Their findings pave the way for potential new treatments to accelerate the healing process in slow-to-heal wounds that can occur in people with autoimmune disorders such as type 1 diabetes.
0 comments - Posted Apr 21, 2010
The first human trials of the latest design of an artificial pancreas for people with type 1 diabetes found the device worked without causing low blood sugar (hypoglycemia).
9 comments - Posted Apr 18, 2010
(HealthDay News) - If you indulge in moderate drinking, you've probably heard that it might reduce your risk for heart trouble, including stroke.
0 comments - Posted Apr 16, 2010
Four risk factors-all of them preventable-reduce life expectancy among U.S. men by 4.9 years and among U.S. women by 4.1 years, according to a study by the Harvard School of Public Health and the Institute for Health Metrics and Evaluation at the University of Washington. (According to U.N. figures, current U.S. life expectancy is 75.6 years for men and 80.8 years for women.)
0 comments - Posted Apr 15, 2010
A gene that mutated half a billion years ago and now shows up in modern sea creatures could hold the key to understanding a rare form of diabetes. The disease, called diabetes insipidus (not to be confused with diabetes mellitus), causes sufferers to urinate more than three-fourths of a gallon every day. An estimated 41,000 U.S. patients suffer from diabetes insipidus.
1 comment - Posted Apr 13, 2010
The idea of parasitic worms causes a shudder in most people. The very thought of some wriggly segmented thing latching onto an internal organ and ransacking it for nourishment is not pleasant. But the scientists who study the creatures may be on to a whole new tack in the fight against type 1 diabetes. It turns out that people who suffer from parasitic worms experience an unexpected beneficial side effect: the worms exert control over the human immune system that seems to protect against several inflammatory diseases, including asthma, Crohn's disease, multiple sclerosis, allergies, and... type 1 diabetes.
0 comments - Posted Apr 12, 2010
The first concrete evidence of a genetic link between low birth weight and the potential for developing type 2 diabetes has been published in the April 6 issue of the journal Nature Genetics. Scientists previously believed that lower birth weight babies were more at risk, but the cause remained unclear.
0 comments - Posted Apr 11, 2010
Healthy, insulin-producing beta cells in the pancreas have a relatively long life and typically do not replicate under normal conditions. Any loss of beta cells, therefore, is usually permanent. In the case of type 1 diabetes, for example, the destruction of beta cells by the body's own immune system is permanent.
2 comments - Posted Apr 9, 2010
Using a sophisticated nanotechnology-based "vaccine," researchers were able to successfully reverse type 1 diabetes in mice and slow the onset of the disease in mice at risk for the disease. The study, co-funded by the Juvenile Diabetes Research Foundation, provides new and important insights into understanding how to stop the immune attack that causes type 1 diabetes, and could even have implications for other autoimmune diseases.
2 comments - Posted Apr 9, 2010
Tests of an experimental drug called CPSI-1306 at Ohio State University were so successful at lowering inflammation and blood sugar levels in lab mice with type 2 diabetes that scientists consider it a prime candidate to become a new therapy for the disease.
0 comments - Posted Apr 8, 2010
After generations of warnings that obesity is one of the biggest risk factors for heart failure and cardiovascular disease, a University of Rochester study says that it's actually skinny people who run a higher risk of sudden death from cardiac failure. Scientists at the University of Rochester Medical Center in New York found that non-obese patients who suffered heart failure had a 76 percent greater risk of sudden cardiac death than obese patients.
2 comments - Posted Apr 3, 2010
A University of Texas researcher who genetically modified mice with type 1 diabetes to control their disease with leptin instead of insulin is now ready to extend his experiment to human test subjects. Dr. Roger Unger, a researcher at the UT Southwestern Medical School in Dallas, will begin the tests as soon as leptin manufacturers can assure him of a steady supply of the hormone.
2 comments - Posted Mar 27, 2010
According to researchers at the Emory University School of Medicine, obesity and metabolic syndrome may be partially brought on by intestinal bacteria that increase appetite and insulin resistance. The two can lead to overeating and high blood sugar levels - both important factors in the eventual onset of type 2 diabetes. Perhaps even more interesting, the scientists found that the bacteria can be transferred from one mouse to another, creating increased appetite and insulin resistance in an animal that had previously experienced neither.
0 comments - Posted Mar 26, 2010
You may not have heard of GAD, but it's a hot topic in the world of type 1 diabetes research. GAD, which stands for glutamic acid decarboxylase, is an enzyme in the brain and the pancreas that plays several roles in the body. As an enzyme, it converts the excitatory amino acid glutamate into the inhibitory neurotransmitter GABA, which nerve cells use to communicate. But it also has a less helpful role, as an autoantigen (an element of self that provokes the generation of antibodies) in autoimmune diabetes.
4 comments - Posted Mar 23, 2010
Results from a landmark study involving more than 9,000 people showed that the high blood pressure medicine valsartan (Diovan) delayed progression to type 2 diabetes in patients with cardiovascular disease or risk factors and impaired glucose tolerance (IGT), a common pre-diabetic condition.
0 comments - Posted Mar 20, 2010
I grew up around the corner from the National Institutes of Health (NIH). In high school, long ago, I thought that NIH scientists were "bad guys" who mistreated animals in the name of medical research. I later moved to the West Coast and became a registered obstetrical nurse. Over the years, along with sharing the joys of new moms and new babies, I cared for patients with devastating conditions like cancer and quadriplegia, people whose lives could potentially be saved or improved by medical research., Yet it wasn't until many years later, after moving back to the DC area, that I really began to see the NIH in a new light.
4 comments - Posted Mar 20, 2010
According to Duke University researchers, a mutation that causes the lack of an insulin-controlling molecule may be a factor in the development of type 2 diabetes. The molecule, ankyrin B, is activated in response to the smell and taste of food and leads to the production of insulin in preparation for food intake.
1 comment - Posted Mar 19, 2010
In a study that tracked 1,402 people with pre-diabetes, researchers found that only about half of them responded to the diagnosis by trying to shed weight or increase their level of exercise.
7 comments - Posted Mar 18, 2010
A group of Swedish researchers has found that men who consume more than the recommended daily amount of calcium are less likely to die than their counterparts who consume little calcium. Their study, titled "Dietary Calcium and Magnesium Intake and Mortality: A Prospective Study of Men," appears in the American Journal of Epidemiology.
2 comments - Posted Mar 15, 2010
A scientist's discovery that dolphins have a genetic ability to turn diabetes on and off, depending on the availability of food, could lead to research into whether humans might have a similar-although dormant-gene.
1 comment - Posted Mar 13, 2010
The sooner people with diabetes start taking metformin, the longer the drug remains effective, according to a Kaiser Permanente study published in the March issue of Diabetes Care, a journal of the American Diabetes Association.
2 comments - Posted Mar 12, 2010
A university study of 20,000 Chinese adults aged 50 and older says that people who nap four to six days a week have a higher rate of type 2 diabetes than people who either never take a daily snooze or do so less often.
2 comments - Posted Mar 10, 2010
Santa Clara County, the largest county in Northern California (nearly 1.9 million people), has filed a federal lawsuit against pharmaceutical company GlaxoSmithKline, alleging that Glaxo knowingly sold its type 2 diabetes drug Avandia for several years despite indications the drug causes heart attacks and strokes.
0 comments - Posted Mar 9, 2010
The benefits of using insulin to treat diabetes far outweigh the risks, but a review just published online by IJCP, the International Journal of Clinical Practice, suggests that commonly used diabetes therapies may differ from each other when it comes to their influence on cancer risk.
1 comment - Posted Mar 5, 2010
The demand for diabetes research funding clearly exceeds the funds available. In the United States, 23.6 million children and adults (7.8 percent of the population) have diabetes, and we spent $174 billion on diagnosed diabetes alone in 2007 (the most recent year for which data are available). It is imperative that we take action, but where is the research funding coming from? Can it possibly be sufficient, and how is it being spent?
3 comments - Posted Mar 3, 2010
An enzyme that destroys pancreatic beta cells in lab mice has now been observed in human beta cells. Because scientists already know how to delete the mouse gene that produces the enzyme, they are hopeful that the same therapy can eventually be applied to people with type 1 diabetes. If so, it would be one of the most powerful therapies yet for addressing the destruction of insulin-producing beta cells that causes type 1.
4 comments - Posted Mar 1, 2010
A hormone responsible for the body's stress response is also linked to the growth of insulin-producing cells in the pancreas, according to JDRF- funded researchers at the Salk Institute for Biological Studies in California. The findings are the latest advances to underscore the potential for regeneration as a key component of a possible cure for type 1 diabetes.
2 comments - Posted Feb 22, 2010
A U.S. Senate Finance Committee report released on February 20 says that Avandia, GlaxoSmithKline's drug for type 2 diabetes, may have caused as many as 83,000 heart attacks between 1999, when the drug was introduced, and 2007. The Senate report, culminating a two-year inquiry into the drug, also says that Glaxo knew about the drug's potential risks years before suspicions began to form regarding a connection between Avandia and heart problems.
2 comments - Posted Feb 22, 2010
Thwarting a protein that carries an otherwise benign enzyme into the nuclei of cells in the retina, where the enzyme kills the retinal cells, may hold the key to preventing blindness in patients with diabetes. That's the conclusion of a two-year study by researchers at Michigan State University seeking a way to treat retinopathy, the disease that often leads to blindness in people with diabetes.
0 comments - Posted Feb 16, 2010
Researchers at RIKEN and Fukuoka University have pinpointed the mechanism responsible for early rejection of transplanted pancreatic islet cells in the treatment of type 1 diabetes. A new system based on this mechanism has been shown to vastly increase transplant efficiency, setting the stage for the development of powerful new treatment techniques.
5 comments - Posted Feb 9, 2010
White fat is the "bad" gut fat associated with obesity and enlarged abdomens. When a pound of new white fat forms in the body, it requires a full mile of new blood vessels to nourish and sustain it. That's because white fat is much like a tumor in requiring a steady blood supply. To build the new blood vessels, it depends on a process called angiogenesis.
1 comment - Posted Feb 8, 2010
In addition to diagnosing type 2 diabetes based on fasting blood glucose levels or a glucose tolerance test, the American Association of Clinical Endocrinologists (AACE) and the American College of Endocrinology (ACE) have now approved the use of A1c as an additional diagnostic criterion for type 2 diabetes.
2 comments - Posted Feb 5, 2010
Australian researchers who tracked the TV viewing habits of 8,800 people over a six-year span have some sobering statistics for people who love the tube too well: (1) If you watch TV more than two and up to four hours a day, your risk of dying from cardiovascular disease increases by 19 percent. (2) If your viewing habit is more than four hours a day, your risk of death from cardiovascular disease skyrockets by 80 percent.
4 comments - Posted Feb 4, 2010
Novo Nordisk announced that the U.S. Food and Drug Administration (FDA) approved the new drug application for Victoza (liraglutide injection), the first once-daily human glucagon-like peptide-1 (GLP-1) analog for the treatment of type 2 diabetes. Victoza is indicated as an adjunct to diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.
4 comments - Posted Jan 28, 2010
An international research consortium has found 13 new genetic variants that influence blood glucose regulation, insulin resistance, and the function of insulin-secreting beta cells in populations of European descent. Five of the newly discovered variants increase the risk of developing type 2 diabetes, the most common form of diabetes.
2 comments - Posted Jan 23, 2010
NEW YORK (Reuters Health) - Diabetes may hasten progression to dementia in older people with mild thinking impairment, new research shows.
2 comments - Posted Jan 19, 2010
NEW YORK, Jan. 14 /PRNewswire-USNewswire/ -- Montefiore Medical Center continues to expand its portfolio of options for patients in need of organ transplantation. The new Pancreas Transplant Program will treat patients with severe, end-stage diabetes. As the only Pancreas Transplant Program in the Bronx and Westchester, and one of only several in Greater New York, patients will be able to receive world-class care close to home. The program currently has nine patients medically approved and waiting for a pancreas transplant.
2 comments - Posted Jan 16, 2010
NEW YORK, January 13, 2010 - The Juvenile Diabetes Research Foundation today announced an innovative partnership with Animas Corporation to develop an automated system to help people with type 1 diabetes better control their disease - the first step on the path to what would be among the most revolutionary advancements in treating type 1 diabetes: the development of an artificial pancreas, a fully automated system to dispense insulin to patients based on real-time changes in blood sugar levels.
9 comments - Posted Jan 15, 2010
One potential avenue for the treatment for type 1 diabetes is to transplant insulin-producing islet cells into the body. The Edmonton Protocol is a method of implanting pancreatic islets into the liver for the treatment of type 1 diabetes. The protocol is named for the islet transplantation group at the University of Alberta in Edmonton, Canada, where the protocol was first devised in the late 1990s.
3 comments - Posted Jan 13, 2010
MADISON, Wis. - Using one of the two major national diabetes screening guidelines misses about one-third of those with diabetes, consequently putting them at risk for serious health complications, according to surprising research findings at the University of Wisconsin School of Medicine and Public Health.
0 comments - Posted Jan 13, 2010
BEDFORD, Mass. and BURGDORF, Switzerland, Jan. 5 /PRNewswire-FirstCall/ -- Insulet Corporation (Nasdaq: PODD), the leader in tubing-free insulin pump technology with its OmniPod® Insulin Management System, and Ypsomed AG (SIX Swiss Exchange: YPSN), a leading independent diabetes specialist and technology provider of innovative injection systems for self-medication in Europe, today announced an exclusive agreement for the distribution of the OmniPod Insulin Management System in nine countries across Europe, as well as China and Australia.
0 comments - Posted Jan 7, 2010
BOSTON, Mass. - Dec. 23, 2009 - Cells in your body are constantly churning out poisonous forms of oxygen (oxidants) and mopping them up with a countervailing force of proteins and chemicals (anti-oxidants). This balancing act of oxidative stress is particularly likely to go haywire in beta cells, the insulin-producing cells that malfunction and then start to die off in type 2 diabetes.
2 comments - Posted Dec 29, 2009
BOSTON/NEW YORK, Dec 23 (Reuters) - The shares of Amylin Pharmaceuticals Inc (AMLN.O) fell nearly 10 percent on Wednesday after the U.S. Food and Drug Administration requested that the company conduct additional safety studies on its diabetes drug, Byetta.
1 comment - Posted Dec 28, 2009
A 20-year study that tracked 704 women from before their first pregnancy onward suggests that the first year mothers breastfeed, they reduce their risk of acquiring type 2 diabetes within the next 15 years by 15 percent. Each subsequent year of breastfeeding further reduces the risk by 15 percent. For example, a mother who has two children and breastfeeds each for a year could enjoy a 30 percent reduction in her risk of type 2 over a 15-year period.
2 comments - Posted Dec 25, 2009
FRIDAY, Dec. 18 (HealthDay News) -- Blacks tend to carry around less of a particularly unhealthy type of abdominal fat than whites, even though they suffer more from obesity-linked illness, researchers report.
0 comments - Posted Dec 23, 2009
Rituxamab, a drug that treats lymphoma and rheumatoid arthritis, may soon be used to help combat the destruction of pancreatic beta cells in newly diagnosed cases of type 1 diabetes. Researchers at Indiana University have found that the drug, originally developed and sold by Genentech as Rituxan, temporarily slows or stops the destruction of the 10 or 20 percent of beta cells that type 1s typically have remaining when they are first diagnosed.
0 comments - Posted Dec 21, 2009
NEW YORK, Dec. 17, 2009 - The Juvenile Diabetes Research Foundation, a leader in setting the agenda for diabetes research worldwide, said today that it will begin working with The Johnson & Johnson Corporate Office of Science and Technology, and its affiliates, to speed the development of drug targets and pathways to promote the survival and function of insulin-producing cells in people who have diabetes. The program will look to fund research at academic centers around the world that could eventually lead to novel drug targets and industry collaborations for the treatment of type 1 diabetes.
2 comments - Posted Dec 19, 2009
WASHINGTON, Dec. 15 /PRNewswire-USNewswire/ -- A 21-year old Airman severely wounded in Afghanistan is recovering at Walter Reed Army Medical Center after several surgeries and an unprecedented transplant.
2 comments - Posted Dec 17, 2009
A gene named HHEX/IDE, which has already been implicated in the development of type 2 diabetes (see research article), may also contribute to childhood obesity. While the gene does not appear to affect birth weight and does not necessarily predispose an adult to become obese, it may set the stage for obesity in some children.
0 comments - Posted Dec 16, 2009
CHICAGO - Individuals who drink more coffee (regular or decaffeinated) or tea appear to have a lower risk of developing type 2 diabetes, according to an analysis of previous studies reported in the December 14/28 issue of Archives of Internal Medicine. A previously published meta-analysis suggested drinking more coffee may be linked with a reduced risk, but the amount of available information has more than doubled since.
4 comments - Posted Dec 14, 2009
WORCESTER, Mass., Dec 3, 2009 (GlobeNewswire via COMTEX News Network) -- Published in the journal Diabetes, Obesity and Metabolism, an independent review of clinical trials of Generex Oral-lyn(TM) shows that the oral insulin spray has a faster onset of action and shorter duration of action than insulin delivered subcutaneously.
6 comments - Posted Dec 9, 2009
We'd all prefer it if there were no nasty side effects to our treatments, but that isn't always the case. Sometimes it is worth risking a side effect for the greater good of our health. On that note, researchers continue to emphasize that the benefits of cholesterol-lowering statins on heart disease far outweigh any risk that they might slightly increase the chance of developing diabetes. More studies needs to be done in this area, but in light of the fact that cardiovascular disease is responsible for nearly two-thirds of deaths in people with diabetes and is the number one killer of women in the United States, it seems better to stick with the statins.
2 comments - Posted Dec 8, 2009
Researchers at the Loyola University Medical Center near Chicago report that 20.7 percent of all American adults who have type 2 diabetes are "morbidly obese," a description that applies to people who are 100 or more pounds overweight. The researchers said that the figure for African Americans is even higher, with one out of three type 2s in that group falling under the definition of morbidly obese.
3 comments - Posted Dec 5, 2009
A Swedish biotechnology company, TikoMed AB, has received notice that the U.S. Food and Drug Administration is granting orphan drug designation to its IBsolvMIR® drug for preventing the rejection of transplanted pancreatic islet cells in type 1 patients.
0 comments - Posted Dec 4, 2009
It's been known for some time that omega-3 fatty acids decrease the risk of heart disease, but no one has really known if one dietary source is better than another. For that reason, Lixin Meng, MS, a PhD candidate at the University of Hawaii at Manoa, designed a study to compare sources, types, amounts, and frequencies of omega-3 in diets, while taking into account gender and ethnic groups. The study was presented at the American Heart Association's 2009 Scientific Sessions.
2 comments - Posted Dec 2, 2009
"Fat is better in the butt than in the gut," in the words of Nancy Bohannon, MD, FACP, FACE, Director of the Clinical Research Cardiovascular Risk Reduction Program in San Francisco. Dr. Bohannon explained in a recent CA-AADE conference that fat is supposed to be subcutaneous. But when you have too much fat, your body has nowhere to put it, so it starts parking it where it doesn't belong-in the muscles or around the heart. This visceral fat, or belly fat, is the bad kind of fat, and it puts stress on the body and organs, including the heart.
0 comments - Posted Dec 1, 2009
A study presented at the American Heart Association's 2009 Scientific Sessions said that eight percent of obese people misunderstand their body size and don't feel they need to lose weight.
3 comments - Posted Nov 30, 2009
Dr. Jennie C. Brand-Miller, from the University of Sydney stated that, "The food insulin index (FII) may provide a better way to adjust insulin dose in Type 1 diabetes.... In time, it may also enable us to design diets to prevent diabetes."
2 comments - Posted Nov 26, 2009
ORLANDO, Fla. Nov. 16, 2009 - In combination with statins, adding a medication that raises high-density lipoprotein (HDL) cholesterol was more effective in reversing artery wall plaque buildup and in reducing heart disease risk than adding a drug that lowers low-density lipoprotein (LDL) cholesterol, researchers reported today at the American Heart Association Scientific Sessions 2009.
1 comment - Posted Nov 20, 2009
The body's immune system is supposed to "tolerate" itself and distinguish "self" from "non-self." Autoimmune diseases such as type 1 diabetes result from the breakdown of this system, causing immune cells to attack and destroy insulin-producing beta cells or "self." In the November issue of Nature Immunology, Brian Fife, PhD and collaborators including senior author Jeffrey Bluestone, PhD share how they have uncovered a basic process that helps control immune cell activation and tolerance.
0 comments - Posted Nov 17, 2009
The Genetic Information Non-discrimination Act of 2008 (GINA) was signed into law by former President George W. Bush on May 21, 2008, and is set to become effective Nov. 21, 2009. The law covers all employers with 15 or more employees. It prohibits employers from considering a person's genetic background in promotions, hiring, or firing. It also prohibits health insurers from using genetic information to deny coverage.
0 comments - Posted Nov 16, 2009
How careful should healthcare workers and patients be in describing a total remission of diabetes as a "cure?" That's a question that has taken on increasing urgency in the wake of reports about dramatic reversals of type 2 symptoms after gastric bypass surgery and the cessation of symptoms in people with type 1 diabetes after pancreatic islet replacement. To answer it, a group of endocrinologists met earlier this year to come up with descriptions and definitions that accurately describe what happens when people with diabetes experience a reversal of symptoms.
2 comments - Posted Nov 14, 2009
Princeton, NJ - November 10, 2009 -- Diabetic foot ulcers are the primary cause of hospital admissions for diabetics. Foot ulcers that heal improperly are at risk for infection, which can lead to amputation. According to the American Diabetes Association, one in four patients with diabetic foot ulcers will eventually require lower-limb amputation. Now science has found a way of mobilizing stem cells within the body to treat this health issue, which affects more than three million Americans annually.
0 comments - Posted Nov 11, 2009
The American Association of Clinical Endocrinologists (AACE) and the College of Endocrinology (ACE) released online a one-page resource for physicians and healthcare providers for the management of glycemic control in type 2 diabetes.
2 comments - Posted Nov 7, 2009
While the relationship between Alzheimer's and diabetes is far from clear, there does seem to be an interesting connection. And that connection just became a little more complicated according to a French study published in the October 27th issue of the journal Neurology.
0 comments - Posted Oct 29, 2009
A South African university pharmacologist has found that simultaneous consumption of metformin and grapefruit juice raises lactic acid to dangerous levels in rats (and conceivably in people) with type 2 diabetes. Too much acid in the blood can cause low pH levels that interfere with the body's metabolic functions. Conceivably, says Dr. Peter Owira, a pharmacologist at the University of KawZulu-Natal, such low levels could be fatal.
5 comments - Posted Oct 26, 2009
NEW YORK (Reuters Health) - A number of traditional Chinese herbs may help control blood sugar levels in people at high risk of diabetes, a new research review suggests.
0 comments - Posted Oct 22, 2009
A study of healthcare claims by 8.75 million health plan members and 632,000 Medicare patients has shown that healthcare costs for the serious consequences of diabetes are significantly lower for people who have been referred to diabetes educators. The savings accrued not at the level of primary or preventive outpatient services, but in the realm of acute inpatient services. In the commercial group, for example, insurees with diabetes education actually had higher outpatient claims than those who had not received education. Their claims for acute inpatient services, however, were considerably lower, indicating that diabetes education had allowed them to avoid some of the disease's harsher outcomes.
1 comment - Posted Oct 22, 2009
A large Kaiser Permanente study, published this month in Diabetes Care, has found that women with diabetes are 26 percent more likely to develop the very rapid and irregular heartbeat known as atrial fibrillation (AF) than women without diabetes. Although not a killer on its own, AF is a serious condition that requires medical treatment and can cause complications. In addition to fatigue, the poor circulation that results from AF can lead to blood pooling and clotting, ultimately causing a stroke.
3 comments - Posted Oct 21, 2009
NEW YORK (Reuters Health) Oct 13 - Women with metabolic syndrome in early pregnancy have a higher risk for preterm birth, according to study findings reported in the October 1st issue of the American Journal of Epidemiology.
0 comments - Posted Oct 16, 2009
October 12, 2009. Philadelphia, Pa. - Children in Philadelphia who attended public schools and shopped at corner stores before or after school purchased almost 360 calories of foods and beverages per visit, according to new research published in the journal Pediatrics. Chips, candy and sugar-sweetened beverages were the most frequently purchased items. This is the first study to document both what foods and beverages children purchased in local corner stores on their way to and from school, and the nutritional content of those items.
0 comments - Posted Oct 15, 2009
The human body is an amazing machine. The biological clock that ticks inside us to keep the machine running efficiently not only prompts us to sleep and eat on regular basis, but also apparently regulates blood sugar.
1 comment - Posted Oct 15, 2009
"Self-monitoring blood glucose" (SMBG), a staple in the lives of most people with diabetes who take insulin, involves consistently monitoring and recording blood glucose levels before and after specific activities, such as eating, exercising, sleeping, and taking insulin. By observing the effects of certain foods and activities on their blood glucose levels, patients can learn exactly what works to raise or lower them. Thus, SMBG affords a kind of "fine tuning" approach to diabetes that empowers patients to adjust their medicine, modify their behavior, and manage their disease without always needing expert intervention.
1 comment - Posted Oct 13, 2009
Hyperglycemia is known to cause microvascular damage, which then creates complications such as proliferative retinopathy. However, this microvascular damage may also affect cognitive functioning even before it is reflected by more easily observed complications such as retinopathy. A study carried out by Eelco van Duinkerken and colleagues in the Netherlands found that "functional connectivity", which is "an indicator of functional interactions and information exchange between brain regions," was different in type 1's as compared to controls.
0 comments - Posted Oct 10, 2009
So close, and yet so far. It looks like there will be no marketing partnership for MannKind's ultra rapid-acting insulin product Afresa anytime soon. The company had planned to enter into a deal with a large pharmaceutical company by the end of this year, but now approval from the Food and Drug Administration (FDA) for their inhaled insulin won't be until January 2010, at the earliest.
3 comments - Posted Oct 8, 2009
The demise of Fen-phen dealt a body blow to hopes for an obesity pill that is actually effective. Unfortunately, the fen in Fen-phen, fenfluramine, caused grave pulmonary hypertension and heart valve problems. The phen part of the drug, though, was apparently just an innocent bystander. And now phen (phentermine) has resurfaced in a new pill that has posted some amazing results in Phase III clinical trials. Patients who were treated for 56 weeks with the new drug, Qnexa, lost an average of 14.7 percent of their weight, or 37 pounds.
8 comments - Posted Oct 7, 2009
A study coming out in the November issue of the Clinical Journal of the American Society of Nephrology is reporting that type 2 men whose blood contained a high count of eosinophils, a sign of allergic inflammation, also had albumin in their urine, which is an early indication of kidney disease. Eosinophils are white blood cells that increase in number during an allergic reaction. Albumin is a protein in the blood that helps regulate blood volume and acts as a carrier for other molecules. Albumin is not normally found in the urine, however, because when healthy kidneys filter the blood, they retain what the body needs (like proteins) and allow only smaller "impurities" into the urine. But during diabetes, too much blood sugar can damage the filtering structures of the kidneys, causing them to thicken and become scarred. Eventually, they begin to leak, and protein (albumin) begins to pass into the urine.
0 comments - Posted Oct 6, 2009
Nature is wonderfully complex. During the second trimester of pregnancy, when the fetus is growing rapidly, hormones from the placenta begin to reduce the ability of the mother's insulin to bind with insulin receptors. Because the mother's insulin is consequently less able to shuttle glucose out of her bloodstream, the growing fetus is guaranteed a good supply of blood glucose.
0 comments - Posted Oct 6, 2009
The enthusiasm for inhaled insulin has waned, to say the least, since Exubera was pulled off the market by Pfizer. Following the Exubera debacle, the development of two other inhaled insulins (AIR by Eli Lilly and Alkermes, and AERx by Novo Nordisk) was halted as well.
14 comments - Posted Oct 5, 2009
Researchers at Children's Hospital in Boston think that they may have created the most reliable means yet of delivering drugs that cannot be taken orally. Their solution is to combine nanotechnology and magnetism to create a delivery system that is simple, but extremely durable and accurate.
2 comments - Posted Oct 3, 2009
"Poor medication adherence," the latest euphemism to replace the much-disliked "poor compliance," is a hot topic these days. According to the New England Health Institute, a third to a half of American patients don't take their medications as prescribed. And people with chronic conditions, including diabetes, are reportedly the worst when it comes to medication adherence and "persistence" (the length of time they continue to take a prescribed drug).
5 comments - Posted Oct 3, 2009
Having diabetes involves a lot of pretty complex arithmetic. You've got to calculate carbs from nutrition labels, total the calories and carbohydrates in a meal, calculate insulin dosage based on insulin-to-carbohydrate intake, and on and on. These tasks aren't simple: They require an understanding of measurement, estimation, time, logic, and multi-step operations, and the knowledge of which math skills to apply to each problem.
3 comments - Posted Oct 2, 2009
The South, which swept a 2009 survey for fattest region, has achieved that dubious honor again when it comes to prevalence of type 2 diabetes. According to a recent study published in Population Health Metrics, it's the region with the highest percentage of type 2 diabetes when both diagnosed and undiagnosed cases are included. Mississippi is at the very top of the heap, followed by West Virginia, Louisiana, Texas, South Carolina, Alabama, and Georgia (15.8 to 16.6 percent for men and 12.4 to 14.8 percent for women).
0 comments - Posted Sep 28, 2009
One thing that really frustrates people with diabetes mellitus is the biopharma industry's focus on treatments rather than cures. A cure is what the diabetes community wants, not another band-aid. So the existence of a biopharma company that calls itself "CureDM" is promising, and its first product, Pancreate, seems to be on its way to fulfilling that promise.
21 comments - Posted Sep 28, 2009
The way information is presented to us makes a big difference in whether we are able to integrate that information into our daily lives. Although graphs and numbers may sway some people, putting educational materials into a culturally relevant context can be more effective. A recent study, for example, has found that a dietary program based on the Medicine Wheel Model for Nutrition can change eating patterns among Native Americans, who have the highest rates of obesity, diabetes, and cardiovascular disease of all ethnic groups.
2 comments - Posted Sep 26, 2009
For most of us, the biggest problem with losing lots of weight is the demoralizing process of watching ourselves gain it all back. But some people who lose weight manage to keep it off for good. How do they do it? Researchers from the Miriam Hospital recently examined their brain activity with functional magnetic resonance imaging and actually saw their restraint in action.
1 comment - Posted Sep 25, 2009
Metformin has always been the old reliable for treating new onset type 2 diabetes, but it's beginning to look like it's got a new calling as a cancer treatment. Diabetes Health recently reported on the fact that metformin reduces a type 2 person's risk of pancreatic cancer by up to 62 percent. It's also been observed that people with type 2 who take metformin have a much lower cancer incidence than those who don't. Now it appears that metformin can help with breast cancer treatment as well. A study of mice with breast cancer generated from human breast cancer cells has found that they remained tumor-free for nearly three months on metformin combined with doxorubicin, a standard cancer chemotherapy. In mice given only the doxorubicin, the tumors recurred.
1 comment - Posted Sep 25, 2009
Scientists have noted for a long time that the hormone leptin suppresses appetite. That's why they have been puzzled by the high levels of leptin found in obese people-shouldn't leptin decrease their appetites and act as a curb on their weight? Leptin also suppresses bone mass accrual, yet obese people do not suffer from loss or weakening of bone mass, despite their high leptin levels.
0 comments - Posted Sep 25, 2009
DAVIS, CA, SEPTEMBER 17, 2009 - While health officials have long suspected the link between obesity and soda consumption, research released today provides the first scientific evidence of the potent role soda and other sugar-sweetened beverages play in fueling California's expanding girth.
4 comments - Posted Sep 24, 2009
By reprogramming skin cells from people with type 1 diabetes, scientists have produced beta cells that secrete insulin in response to changes in glucose levels. Dr. Douglas Melton and his colleagues at the Harvard Stem Cell Institute started by using the skin cells to generate induced pluripotent stem (iPS) cells. Once they had iPS cells, the researchers manipulated them into developing into pancreatic islet (beta) cells.
4 comments - Posted Sep 19, 2009
Researchers at the Karolinsky Institute in Sweden have discovered that in people with type 2 diabetes, a gene in muscle tissue is "methylated"; that is, an extra methyl group is stuck to it, causing it to respond differently. The gene in question, PGC-1α, controls other genes that affect how glucose is metabolized by muscle cells. The end result of methylated PGC-1α is that muscle cells are less able to use glucose as an energy source.
0 comments - Posted Sep 18, 2009
Those of you who are familiar with the South know what kudzu is. An Asian vine that can grow a foot taller every day, it was brought to the American Southeast in the 1930s in a sadly boneheaded attempt to control erosion. Unfortunately, the little green visitor liked it here so much that in the decades since, it has colonized 10 million acres of farms and woods, becoming a massive and costly nuisance.
0 comments - Posted Sep 16, 2009
You might think that people with type 2 diabetes would know better than most what they should put into and leave out of their diets. At least, that was the expectation of researchers at the Wake Forest School of Medicine in Winston-Salem, North Carolina, when they set out to learn why people with type 2 are often overweight. What they found, however, surprised them. Their study of 2,757 type 2s showed that:
7 comments - Posted Sep 15, 2009
An Italian study of people with type 2 diabetes has found that 70 percent of those who followed a low-fat diet eventually needed diabetes drugs, as opposed to only 44 percent of those who ate a Mediterranean diet.
4 comments - Posted Sep 14, 2009
ALEXANDRIA, VA, Sep 01, 2009 (MARKETWIRE via COMTEX) - The American Diabetes Association Research Foundation has selected two scientists, University of Virginia Health System researcher Zhenqi Liu, MD, and Stanford University School of Medicine researcher Gerald Reaven, MD, to receive the American Diabetes Association-Novo Nordisk Clinical/Translational Research Award.
0 comments - Posted Sep 12, 2009
Visceral adipose tissue (VAT), familiarly known as visceral fat, has long been associated with metabolic risk. But VAT is closely correlated with liver fat, also called intrahepatic triglyceride (IHTG) content. As a result, Samuel Klein of the Washington University School of Medicine in St. Louis, Missouri, set out to determine if liver fat is more closely correlated with complications in obese patients than VAT.
0 comments - Posted Sep 12, 2009
Adults newly diagnosed with type 2 diabetes generally don't take to the idea of using insulin right off the bat. They're worried about gaining weight and fear low blood sugars. They're also concerned about whether they can manage the regimen and fear that taking insulin will lower their quality of life. Those concerns, however, might be assuaged by a study recently conducted by Ildiko Lingvay and his colleagues at the University of Texas Southwestern.
5 comments - Posted Sep 12, 2009
Juice extracted from North American lowbush blueberries, biotransformed with bacteria from the skin of the fruit, holds great promise as an anti-obesity and anti-diabetic agent. The study, published in the International Journal of Obesity, was conducted by researchers from the Université de Montréal, the Institut Armand-Frappier and the Université de Moncton who tested the effects of biotransformed juices compared to regular blueberry drinks on mice.
3 comments - Posted Sep 10, 2009
It's not on the market yet, but a patch composed of tiny needles, each the width of a few human hairs, could eventually replace hypodermic needles for most drug injections. Preliminary experiments with people with diabetes have shown that the patch can deliver insulin successfully and with less pain than a hypodermic.
5 comments - Posted Sep 9, 2009
Scientists and healthcare professionals have known for some time that low levels of vitamin D almost double the risk of cardiovascular disease in people with diabetes. But until now, they haven't known why.
1 comment - Posted Sep 8, 2009
A South Carolina study has found that the DASH diet, originally designed to treat hypertension, is linked to a lower rate of type 2 diabetes in whites, but not in blacks or Hispanics.
0 comments - Posted Sep 5, 2009
The famous Diabetes Control and Complications Trial, known to its friends as the DCCT, was the first to prove the power of "intensive control" of blood glucose to reduce the complications of diabetes. Although the ten-year study ended in 1993, researchers have continued to follow about 90 percent of the nearly 1,500 original DCCT volunteers. And the follow-up study, called the Epidemiology of Diabetes Interventions and Complications (EDIC), is measuring up to its illustrious parent in terms of demonstrating the value of tight control. According to results published in the July 27, 2009 issue of the Archives of Internal Medicine, microvascular and cardiovascular complications of type 1 diabetes are cut in half for patients with near-normal glucose.
11 comments - Posted Sep 5, 2009
According to a recent Pennsylvania study, kids need to learn to control themselves when it comes to food. Obviously, self-control is important for us all, kids and adults alike, when it comes to weight management. It’s equally apparent that children need to be taught by their parents to make healthy food choices. But parents who strictly forbid their children to eat many foods might be contributing to a lack of self-control in their offspring, thereby creating the very chubbiness that they were trying to avert.
2 comments - Posted Sep 4, 2009
Even though autumn is just around the corner, many places in the country still have a couple of hot spells left. And those surprise heat waves can be bad news for people with diabetes. It’s no secret that the elderly, the obese, and people with heart disease or respiratory conditions are vulnerable to heat-related illnesses. It’s less well known, however, that people with type 1 and type 2 diabetes are more likely than non-diabetics to suffer heat stroke, heat exhaustion, and heat cramps.
1 comment - Posted Sep 3, 2009
Researchers at Stanford University recently discovered that a mutated version of a gene may contribute to type 1 diabetes by sabotaging the functioning of the gene's normal version. Experiments conducted on mice with a diabetes-type disease showed that the mutated variant may prevent the healthy version from protecting the insulin-producing cells in the pancreas from attack by the immune system.
0 comments - Posted Sep 3, 2009
Eating fat is usually not very helpful when it comes to losing weight. According to a researcher at Ohio State University, however, two natural oils that contain "good fats" can melt away pounds in postmenopausal obese women with type 2 diabetes.
1 comment - Posted Sep 2, 2009
Research by Utah scientists has clarified the mechanism behind the long-held notion that sugar somehow "feeds" tumors. In addition to suggesting a new way to fight cancer, the findings provide insight into how the body metabolizes glucose and may eventually affect treatments for diabetes.
0 comments - Posted Sep 1, 2009
Being a protein can be a dirty, sticky job. Most proteins in the body have carbohydrates stuck all over them. And when a carbohydrate sticks to a protein, it may change the way the protein works or how the protein interacts with other proteins.
1 comment - Posted Aug 28, 2009
A Japanese company whose biggest moneymaker is the sale of synthetic fabrics announced a few days ago that it has developed an insulin nasal spray for people with diabetes. The news brought an investor surge that lifted the value of its stocks by 10 percent.
0 comments - Posted Aug 28, 2009
Our genes are like a recipe for a human. It's a very complicated recipe, determining how much of this protein and how much of that enzyme need to be added into the mix in order for us to function properly, but our genes are pretty good at getting it right. Although we are still learning how the recipe works, what ingredients (gene products) are involved, and when are they are produced, our knowledge is growing fast.
2 comments - Posted Aug 28, 2009
Everyone knows that eating only high fat food is unhealthy way down the road, but we don't really worry that eating a burger will hurt us by next week. Unfortunately, however, it turns out that a high fat diet damages our health (and our brain functioning) a lot sooner than we would like to think. In fact, new research shows that the effects are felt within only ten days. As far as I'm concerned, this was already shown conclusively in the film "Super Size Me," in which director Morgan Spurlock personally examined the effects of fast food on the human body. For one month, he ate only at McDonald's, ordering everything on the menu and "super-sizing" his order whenever asked. Right before our eyes, Spurlock began looking sicker and sicker.
12 comments - Posted Aug 28, 2009
In our last issue, we published a letter from reader Sheila Payne, who wrote that we had been far too positive about continuous glucose monitoring (CGM) in our June/July article Get the Facts on Continuous Glucose Monitoring. But her opinion provoked a stack of letters from people who believe that the benefits of CGM substantially outweigh its negatives. To let you in on the debate, we are reprinting Ms. Payne's thought-provoking letter here, followed by two equally thoughtful responses from readers.
12 comments - Posted Aug 28, 2009
Canadian scientists have reported that a hormone found in the gut has the power to lower glucose production by signaling the brain and liver to do so. When the researchers activated its receptors in lab rats, they found that the hormone, called cholecystokinin (CCK) peptide, rapidly lowered the animals' blood glucose levels.
0 comments - Posted Aug 27, 2009
The PreDx Diabetes Risk Score determines risk of developing type 2 diabetes within five years
0 comments - Posted Aug 26, 2009
A new glucagon-like peptide-1 (GLP-1) analog for type 2s that might require dosing only once a month is now in pre-clinical (animal) studies. GLP-1, which increases insulin secretion from the pancreas, is a mighty helpful molecule, but with a sadly brief lifespan. It's broken down in the body within minutes by the enzyme DPP-4. That's why drugs like Merck's Januvia, a DPP-4 inhibitor, is effective: blocking DPP-4 subsequently increases the amount of GLP-1 in the system.
0 comments - Posted Aug 25, 2009
Deferoxamine, a drug already FDA-approved for the treatment of disorders related to excess iron in the blood, may help doctors heal stubborn leg and foot wounds in people with diabetes. Scientists at the Stanford University School of Medicine and the Albert Einstein College of Medicine found that with deferoxamine, small cuts in diabetic mice healed 10 days faster than they did in untreated mice: 13 days as opposed to 23 days. If deferoxamine works similarly on humans, it could significantly speed the healing of diabetic wounds.
6 comments - Posted Aug 22, 2009
It's called an anti-Ras drug, but it's got no problem with reggae. It's a multi-talented new pill against pancreatic cancer that just might also come to the rescue of pancreatic beta cells. Its pancreatic cancer-fighting attributes are currently being tested in a human clinical trial, but a modified version has been shown to maintain normal insulin production in diabetic mice.
1 comment - Posted Aug 21, 2009
South African researchers have found that in areas where tuberculosis is endemic, nearly one in three children and adolescents with type 1 diabetes tests positive when given a skin test for the disease. Although the positive test results do not mean that these young people will inevitably develop active TB, they do run a very high risk of doing so.
4 comments - Posted Aug 20, 2009
One of the major complications of diabetes is diabetic nephropathy, a loss of kidney function that may lead to renal failure. As kidney disease progresses, the barrier that keeps large molecules out of the urine, called the glomerular barrier, begins to break down. With the barrier failing, certain large molecules begin to migrate into the urine. One of those hefty molecules is immunoglobulin M, or IgM.
1 comment - Posted Aug 19, 2009
The theory of unintended consequences has gotten another boost. Although two drugs designed to slow the loss of kidney function in people with typ