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Latest The Cure Articles
The Diabetes Cure Article Archives
September 2011
Imagine if there were a cure for diabetes that could be found inside your own body? Wouldn't it be nice if instead of depending on durable medical equipment, we could one day heal ourselves?
1 comment - Posted Sep 24, 2011
March 2011
If a prisoner on death row wants to donate his organs, should he be allowed to do it?
21 comments - Posted Mar 18, 2011
February 2011
Can't make insulin? That might not be a problem, according to Dr. Roger Unger, the lead researcher on a mouse study out of UT Southwestern Medical Center. As Dr. Unger stated in a press release, his findings "suggest that if there is no glucagon, it doesn't matter if you don't have insulin....In adulthood, at least with respect to glucose metabolism, the role of insulin is to control glucagon. And if you don't have glucagon, then you don't need insulin...If diabetes is defined as restoration of glucose homeostasis to normal, then this treatment can perhaps be considered very close to a ‘cure.' "
1 comment - Posted Feb 16, 2011
The final patient has performed the last visit of the main study period in Diamyd Medical's European Phase III study. Treatment with the antigen based therapy Diamyd® is made to investigate whether beta cell function and thereby blood sugar control can be preserved in children and adolescents with new onset type 1 diabetes. The top line results from this study are expected to be reported as planned, in late spring 2011.
0 comments - Posted Feb 15, 2011
It's generally thought that a genetic predisposition to type 1 diabetes is not enough to develop the disease, but that an environmental trigger is required to activate it. Researchers are not sure what that environmental trigger is, but enteroviruses have been under suspicion for quite a while. Enteroviruses are the second leading cause of viral colds in children.
1 comment - Posted Feb 8, 2011
INDIANAPOLIS and NEW YORK - Eli Lilly and Company and the Juvenile Diabetes Research Foundation (JDRF) today announced that they have signed an agreement to fund early-stage research that could enable patients with type 1 diabetes to regenerate insulin-producing cells destroyed by the disease.
0 comments - Posted Feb 4, 2011
January 2011
The MOLLY and LINDSEY Diabetes Research Foundation at Hackensack University Medical Center (HUMC) and the Diabetes Research Institute (DRI), a Center of Excellence at the University of Miami Miller School of Medicine, have joined forces to find the cure for Type 1 Diabetes. Together they will form the Hackensack-Miami DRI Federation Project, a think tank of East Coast specialists who will fast-track the best research ideas coming out of the labs and put them to the test in clinically meaningful ways, thus shortening the path to a cure for those with type 1 diabetes.
5 comments - Posted Jan 26, 2011
December 2010
(Reuters) - Stem cells can be transformed into the pancreatic cells needed to treat diabetes and into complex layers of intestinal tissue, scientists demonstrated in two experiments reported on Sunday.
6 comments - Posted Dec 13, 2010
"Congress passed a multi-year renewal of the Special Diabetes Program (SDP), ensuring that studies on promising diabetes treatments and avenues toward a cure continue uninterrupted. As the father of a son living with type 1 diabetes, and as CEO of JDRF, one of the leading advocates for the renewal of this program, I applaud the U.S. government for its continued commitment to end this disease.
2 comments - Posted Dec 13, 2010
Celebrate the season with an eCard and help support the Diabetes Research Institute! Send your family, friends or business colleagues A Gift of Love...A Gift of Hope. They will feel special knowing you are supporting research to find a cure for diabetes.
0 comments - Posted Dec 3, 2010
November 2010
Hundreds of people like you are choosing to Be Part of Cure. They are sharing their personal experiences - both heartbreaking and inspiring - of how diabetes has touched their lives.
0 comments - Posted Nov 13, 2010
September 2010
The presence of amyloid protein may produce a chain reaction which destroys vital insulin-producing cells. Researchers based in Dublin, writing in the journal Nature Immunology, say future drugs could target this process. Amyloid is implicated in many other diseases - most notably Alzheimer's.
0 comments - Posted Sep 17, 2010
In type 1 diabetes, the body relentlessly attacks and destroys its own insulin-producing pancreatic beta cells. But a study by Joslin Diabetes Center scientists now has firmly established that some of these cells endure for many decades in a small group of people with the disease-offering clues to potential treatments for preserving and even restoring the crucial cell population.
0 comments - Posted Sep 14, 2010
The exact cause of type 1 diabetes is still unknown, but international researchers have found a link between the blood sugar disorder and a network of immune system genes.
0 comments - Posted Sep 13, 2010
August 2010
On Monday, August 23rd, a federal court blocked federal funding of embryonic stem cell research; ruling that the Obama Administration's policy violates federal law.
0 comments - Posted Aug 31, 2010
MannKind Corporation announced that the company will supply its novel, ultra rapid acting insulin AFREZZATM (insulin human [rDNA origin]) for use in a study being conducted by the Juvenile Diabetes Research Foundation (JDRF) as part of its Artificial Pancreas Project. The planned two-year study in patients with type 1 diabetes will leverage the unique rapid action of AFREZZA for use in a closed-loop blood sugar monitoring and insulin delivery system, termed the "artificial pancreas" by the JDRF. The study will be managed in conjunction with the Sansum Diabetes Research Institute and the University of California, Santa Barbara.
0 comments - Posted Aug 29, 2010
"The objective of this clinical trial (research study) is to determine if the medications can rescue the few beta cells that remain soon after the diagnosis of type 1 diabetes; and whether new beta cells can even be regenerated," commented Alex Rabinovitch, MD, Principal Investigator of the trial and Associate Director of The Sanford Project. "The investigational combinations of these medications could possibly allow patients to decrease or no longer need to inject insulin to keep their blood levels under proper control."
0 comments - Posted Aug 12, 2010
June 2010
City of Hope researchers have found that bone marrow transplantation with islet cell transplantation shows promise as a treatment for late-stage type 1 diabetes. This combination may enable patients to make their own insulin again. Results from laboratory research led by Defu Zeng, MD, associate professor in the departments of Diabetes Research and Hematology & Hematopoietic Cell Transplantation at City of Hope, were published online this month in the journal Diabetes.
0 comments - Posted Jun 25, 2010
Researchers from the National Jewish Health and University of Colorado Anschutz Medical Campus have found a specific protein fragment, or peptide, that stimulates an immune system attack resulting in diabetes. Their experiments in mice contradict conventional wisdom about such peptides and support work by scientists studying autoimmune diseases.
0 comments - Posted Jun 24, 2010
IMIDIA ("Innovative Medicines Initiative for Diabetes"), a public private consortium funded by the Innovative Medicines Initiative (IMI), announced today the launch of a project focusing on pancreatic islet cell function and survival. Academia, biotech and pharma industry have joined forces to develop biomarkers and tools to pave the way for improved disease management and ultimately provide a cure for diabetes.
0 comments - Posted Jun 18, 2010
Italian researchers have found a link between a common virus and type 1 diabetes that may open the door to answers about what triggers the disease in children.
0 comments - Posted Jun 17, 2010
May 2010
Osiris Therapeutics announced that it has been granted Orphan Drug designation from the U.S. Food and Drug Administration (FDA) for Prochymal as a treatment for type 1 diabetes mellitus. The FDA instituted the Orphan Drug Act to promote the development of treatments for underserved patient populations. To be eligible for Orphan Drug designation, the treatment must target a disease that affects fewer than 200,000 new patients per year in the United States.
0 comments - Posted May 7, 2010
April 2010
NEW YORK, April 27, 2010 - The Juvenile Diabetes Research Foundation announced today that it is partnering with Living Cell Technologies (LCT), a New Zealand-based biotechnology company focused on developing cell based therapeutics, in a Phase II clinical trial to study the safety and effectiveness of transplanting encapsulated insulin-producing cells from pigs as a treatment for type 1 diabetes with significant hypoglycemia unawareness.
1 comment - Posted Apr 28, 2010
Using a sophisticated nanotechnology-based "vaccine," researchers were able to successfully reverse type 1 diabetes in mice and slow the onset of the disease in mice at risk for the disease. The study, co-funded by the Juvenile Diabetes Research Foundation, provides new and important insights into understanding how to stop the immune attack that causes type 1 diabetes, and could even have implications for other autoimmune diseases.
2 comments - Posted Apr 9, 2010
February 2010
A hormone responsible for the body's stress response is also linked to the growth of insulin-producing cells in the pancreas, according to JDRF- funded researchers at the Salk Institute for Biological Studies in California. The findings are the latest advances to underscore the potential for regeneration as a key component of a possible cure for type 1 diabetes.
2 comments - Posted Feb 22, 2010
November 2009
How careful should healthcare workers and patients be in describing a total remission of diabetes as a "cure?" That's a question that has taken on increasing urgency in the wake of reports about dramatic reversals of type 2 symptoms after gastric bypass surgery and the cessation of symptoms in people with type 1 diabetes after pancreatic islet replacement. To answer it, a group of endocrinologists met earlier this year to come up with descriptions and definitions that accurately describe what happens when people with diabetes experience a reversal of symptoms.
2 comments - Posted Nov 14, 2009
August 2009
There's a gene whose name you should remember because it could mark a crucial point in the war on type 1 diabetes.
3 comments - Posted Aug 13, 2009
March 2009
These amazing teens-selected from 20,000 entries nationwide-were named State Honorees (along with 102 other state winners throughout the U.S.) in the 14th annual Prudential Spirit of Community Awards, a national program honoring middle and high school students for their outstanding acts of volunteerism. The program is conducted by Prudential Financial and the National Association of Secondary School Principals. Over the past 14 years, they have honored more than 80,000 young volunteers at the local, state, and national levels.
1 comment - Posted Mar 17, 2009
"Medical miracles do not happen simply by accident," said President Obama, as he signed an executive order lifting the ban on federally funded embryonic stem cell research. The Juvenile Diabetes Research Foundation (JDRF) is celebrating President Obama's new policy. They recently released this statement by Mary Tyler Moore, the International Chairman of the JDRF:
12 comments - Posted Mar 17, 2009
January 2009
Nearly every time that I mention islet transplantation in a conversation about diabetes, the person I'm with responds with a sniff that it's never going to work because of the immune suppression problem.
12 comments - Posted Jan 23, 2009
December 2008
The first time I presented medical research findings, I was not yet a physician. The year was about 1975. I was in my early forties and a mid-career engineer. The forum was a scientific symposium on diabetes. At the time, I felt that I had discovered the holy grail of diabetes care and was eager to share what I had learned.
22 comments - Posted Dec 8, 2008
I am always impressed when people find the strength to turn their own painful experience into a way to help others. In case you are losing faith that people are out there raising money, trying to find the Cure, and taking care of each other...read on.
1 comment - Posted Dec 8, 2008
September 2008
To keep pace with the growing number of Americans with diabetes, the American Diabetes Association (ADA) invites communities nationwide to their brand new fundraising walk, Step Out: Walk to Fight Diabetes.
3 comments - Posted Sep 11, 2008
August 2008
In March, Diabetes Health reported on Dr. Francesco Rubino, a surgeon who claims that the origin of diabetes is in the digestive system, not the gut, and that gastric bypass surgery cures type 2 diabetes.
0 comments - Posted Aug 28, 2008
A study of beta cells at McGill University Health Centre in Montreal could hold significant promise for people with type 1 diabetes.
0 comments - Posted Aug 5, 2008
June 2008
Twenty-four diabetes doctors and researchers from the United States, Canada, the United Kingdom, Finland, Sweden and Portugal have published a study criticizing the American Diabetes Association (ADA) assertion that diabetics should consume no fewer than 130 mg of carbohydrates daily and the European Association for the Study of Diabetes (EASD) statement that low-carb diets are “not justified.”
28 comments - Posted Jun 26, 2008
Tekturna Reduces Kidney Disease Indicator
The blood pressure medicine Tekturna (aliskiren) may have a beneficial side effect for people with type 2 diabetes and high blood pressure who are at risk of kidney disease. According to a recent article in The New England Journal of Medicine, the drug reduces proteinuria, a key indicator of kidney disease, by 20 percent in patients with type 2 diabetes.
2 comments - Posted Jun 26, 2008
Clinical trials have been a staple of diabetes research ever since 1922, when doctors in a Toronto hospital injected a young boy dying from the disease with pancreatic extracts. (The extracts contained the recently discovered hormone, insulin. The boy survived and lived another 13 years.)
3 comments - Posted Jun 19, 2008
March 2008
Talk of a cure has been around forever. Sometimes it seems as if the cure is a constantly receding dream, always ten years away or just around the next corner.
12 comments - Posted Mar 9, 2008
September 2007
Since the 1950s, the National Institutes of Health (NIH) has funded almost all diabetes research worldwide. From its headquarters in Bethesda, Maryland, the NIH oversees a $28 billion annual medical research budget. More than $1 billion of those taxpayer dollars go specifically toward diabetes research. Still, a cure remains frustratingly elusive.
0 comments - Posted Sep 13, 2007
February 2007
MINNEAPOLIS, Minn. - For the millions of people worldwide who are afflicted with diabetes, we are now one step closer to a potential cure for the disease. Spring Point Project, a non-profit organization created to expedite the widespread availability of islet tissue for diabetes care, will open its first biosecure animal facility in Western Wisconsin in February to hold high-health pathogen-free pigs. Insulin-producing islet cells from pigs are needed to meet the demands that cannot be realized by using transplantation of human islets.
0 comments - Posted Feb 28, 2007
June 2006
Two and a half years ago, the journal Science published results from Denise Faustman’s groundbreaking study in which type 1 diabetes was reversed in non-obese diabetic mice injected with a combination of an immune adjuvant and spleen cells. Recently, researchers at the University of Chicago, Washington University in St. Louis and Harvard’s Joslin Clinic all partially replicated Dr. Faustman’s research.
0 comments - Posted Jun 1, 2006
March 2004
In November 2003 the news was everywhere. “Juvenile diabetes cured in lab mice!” proclaimed the November 14, 2003, edition of The Boston Globe.
6 comments - Posted Mar 1, 2004
June 2002
Researchers may have discovered a protein in the liver that could lead to a cure for type 2 diabetes, according to a new study published in the February 19, 2002, issue of Nature Genetics. Doctors at the Medical College of Ohio found that this protein, called CEACAM1, helps to clear insulin from the blood.
0 comments - Posted Jun 1, 2002
December 2001
Someday, a cure for diabetes will be found. But the question still remains about it how it will happen. By regenerating our own cells? Or maybe by transplanting islets from pigs into humans?
0 comments - Posted Dec 1, 2001
September 2001
A 40-day treatment of type 1 diabetes was shown to cure the disease in mice, say researchers from Massachusetts. The encouraging results could lead to finding a cure for diabetes in humans, they say.
0 comments - Posted Sep 1, 2001
September 2000
On July 13, President Clinton announced the 10 centers chosen to replicate the Edmonton Protocol.
0 comments - Posted Sep 1, 2000
November 1992
Fetal tissue. No other topic in diabetes research is as emotionally stirring. Some say that fetal tissue is the key to progress, and perhaps that fetal tissue will even cure diabetes. Others claim that fetal tissue research is immoral because it produces an incentive for abortions. How important is fetal tissue research? Is it likely to produce a cure for diabetes? Are there alternatives that avoid ethical concerns?
0 comments - Posted Nov 1, 1992