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The Diabetes Cure Article Archives

September 2011

Reproductive Cells May Eventually Treat Type 1 Diabetes

Imagine if there were a cure for diabetes that could be found inside your own body? Wouldn't it be nice if instead of depending on durable medical equipment, we could one day heal ourselves?

comments 1 comment - Posted Sep 24, 2011

March 2011

Should States Let Inmates Donate Organs?

If a prisoner on death row wants to donate his organs, should he be allowed to do it?

comments 19 comments - Posted Mar 18, 2011

February 2011

Mouse Study Eliminates Need for Insulin by Eliminating Glucagon

Can't make insulin? That might not be a problem, according to Dr. Roger Unger, the lead researcher on a mouse study out of UT Southwestern Medical Center. As Dr. Unger stated in a press release, his findings "suggest that if there is no glucagon, it doesn't matter if you don't have insulin....In adulthood, at least with respect to glucose metabolism, the role of insulin is to control glucagon. And if you don't have glucagon, then you don't need insulin...If diabetes is defined as restoration of glucose homeostasis to normal, then this treatment can perhaps be considered very close to a ‘cure.' "

comments 1 comment - Posted Feb 16, 2011

Last Patient Completes the EU Phase III Study of Diamyd® Antigen Based Therapy for Type 1 Diabetes

The final patient has performed the last visit of the main study period in Diamyd Medical's European Phase III study. Treatment with the antigen based therapy Diamyd® is made to investigate whether beta cell function and thereby blood sugar control can be preserved in children and adolescents with new onset type 1 diabetes. The top line results from this study are expected to be reported as planned, in late spring 2011.

comments 0 comments - Posted Feb 15, 2011

Type 1 Diabetes Associated With Common Cold Virus

It's generally thought that a genetic predisposition to type 1 diabetes is not enough to develop the disease, but that an environmental trigger is required to activate it. Researchers are not sure what that environmental trigger is, but enteroviruses have been under suspicion for quite a while. Enteroviruses are the second leading cause of viral colds in children.

comments 1 comment - Posted Feb 8, 2011

Lilly and the JDRF Partner to Fund Regenerative Medicine Research in Type 1 Diabetes

INDIANAPOLIS and NEW YORK - Eli Lilly and Company and the Juvenile Diabetes Research Foundation (JDRF) today announced that they have signed an agreement to fund early-stage research that could enable patients with type 1 diabetes to regenerate insulin-producing cells destroyed by the disease.

comments 0 comments - Posted Feb 4, 2011

January 2011

New Jersey - Florida Partnership to Speed Diabetes Research: A Cure for Diabetes is One Step Closer

The MOLLY and LINDSEY Diabetes Research Foundation at Hackensack University Medical Center (HUMC) and the Diabetes Research Institute (DRI), a Center of Excellence at the University of Miami Miller School of Medicine, have joined forces to find the cure for Type 1 Diabetes.  Together they will form the Hackensack-Miami DRI Federation Project, a think tank of East Coast specialists who will fast-track the best research ideas coming out of the labs and put them to the test in clinically meaningful ways, thus shortening the path to a cure for those with type 1 diabetes.  

comments 5 comments - Posted Jan 26, 2011

December 2010

Stem cells used to make pancreas, gut cells

(Reuters) - Stem cells can be transformed into the pancreatic cells needed to treat diabetes and into complex layers of intestinal tissue, scientists demonstrated in two experiments reported on Sunday.

comments 6 comments - Posted Dec 13, 2010

JDRF Applauds Congress for Passage of $300 Million for Type 1 Diabetes Research and Thanks Supporters for Advocacy Efforts for Special Diabetes Program Renewal

"Congress passed a multi-year renewal of the Special Diabetes Program (SDP), ensuring that studies on promising diabetes treatments and avenues toward a cure continue uninterrupted. As the father of a son living with type 1 diabetes, and as CEO of JDRF, one of the leading advocates for the renewal of this program, I applaud the U.S. government for its continued commitment to end this disease.

comments 2 comments - Posted Dec 13, 2010

A Gift of Love. A Gift of Hope...For the Holidays.

Celebrate the season with an eCard and help support the Diabetes Research Institute! Send your family, friends or business colleagues A Gift of Love...A Gift of Hope. They will feel special knowing you are supporting research to find a cure for diabetes.

comments 0 comments - Posted Dec 3, 2010

November 2010

Be Part of the Cure

Hundreds of people like you are choosing to Be Part of Cure. They are sharing their personal experiences - both heartbreaking and inspiring - of how diabetes has touched their lives.

comments 0 comments - Posted Nov 13, 2010

September 2010

Rogue Protein May Trigger Diabetes

The presence of amyloid protein may produce a chain reaction which destroys vital insulin-producing cells. Researchers based in Dublin, writing in the journal Nature Immunology, say future drugs could target this process. Amyloid is implicated in many other diseases - most notably Alzheimer's.

comments 0 comments - Posted Sep 17, 2010

Joslin 50-Year Medalists Give Clues to Cures

In type 1 diabetes, the body relentlessly attacks and destroys its own insulin-producing pancreatic beta cells. But a study by Joslin Diabetes Center scientists now has firmly established that some of these cells endure for many decades in a small group of people with the disease-offering clues to potential treatments for preserving and even restoring the crucial cell population.

comments 0 comments - Posted Sep 14, 2010

Immune System Genes Show Links to Type 1 Diabetes

The exact cause of type 1 diabetes is still unknown, but international researchers have found a link between the blood sugar disorder and a network of immune system genes.

comments 0 comments - Posted Sep 13, 2010

August 2010

Blocking Progress

On Monday, August 23rd, a federal court blocked federal funding of embryonic stem cell research; ruling that the Obama Administration's policy violates federal law.   

comments 0 comments - Posted Aug 31, 2010

MannKind Corporation Providing AFREZZA to JDRF for Artificial Pancreas Project

MannKind Corporation announced that the company will supply its novel, ultra rapid acting insulin AFREZZATM (insulin human [rDNA origin]) for use in a study being conducted by the Juvenile Diabetes Research Foundation (JDRF) as part of its Artificial Pancreas Project. The planned two-year study in patients with type 1 diabetes will leverage the unique rapid action of AFREZZA for use in a closed-loop blood sugar monitoring and insulin delivery system, termed the "artificial pancreas" by the JDRF. The study will be managed in conjunction with the Sansum Diabetes Research Institute and the University of California, Santa Barbara.

comments 0 comments - Posted Aug 29, 2010

The Sanford Project Launches Research Study to Find a Cure

"The objective of this clinical trial (research study) is to determine if the medications can rescue the few beta cells that remain soon after the diagnosis of type 1 diabetes; and whether new beta cells can even be regenerated," commented Alex Rabinovitch, MD, Principal Investigator of the trial and Associate Director of The Sanford Project. "The investigational combinations of these medications could possibly allow patients to decrease or no longer need to inject insulin to keep their blood levels under proper control."

comments 0 comments - Posted Aug 12, 2010

June 2010

Double Transplantation Treatment for Type 1 Diabetes

City of Hope researchers have found that bone marrow transplantation with islet cell transplantation shows promise as a treatment for late-stage type 1 diabetes. This combination may enable patients to make their own insulin again.  Results from laboratory research led by Defu Zeng, MD, associate professor in the departments of Diabetes Research and Hematology & Hematopoietic Cell Transplantation at City of Hope, were published online this month in the journal Diabetes.

comments 0 comments - Posted Jun 25, 2010

Scientists Have Found the Peptide Trigger for Type 1 Diabetes in Animal Tests

Researchers from the National Jewish Health and University of Colorado Anschutz Medical Campus have found a specific protein fragment, or peptide, that stimulates an immune system attack resulting in diabetes. Their experiments in mice contradict conventional wisdom about such peptides and support work by scientists studying autoimmune diseases.

comments 0 comments - Posted Jun 24, 2010

Academia, Biotech and the Pharmaceutical Industry Have Joined Forces to Fight Diabetes

IMIDIA ("Innovative Medicines Initiative for Diabetes"), a public private consortium funded by the Innovative Medicines Initiative (IMI), announced today the launch of a project focusing on pancreatic islet cell function and survival. Academia, biotech and pharma industry have joined forces to develop biomarkers and tools to pave the way for improved disease management and ultimately provide a cure for diabetes.

comments 0 comments - Posted Jun 18, 2010

Italian Scientists Find a Viral Link to Type 1 Diabetes

Italian researchers have found a link between a common virus and type 1 diabetes that may open the door to answers about what triggers the disease in children.

comments 0 comments - Posted Jun 17, 2010

May 2010

Stem Cell Treatment for Type 1 Diabetes

Osiris Therapeutics announced that it has been granted Orphan Drug designation from the U.S. Food and Drug Administration (FDA) for Prochymal as a treatment for type 1 diabetes mellitus. The FDA instituted the Orphan Drug Act to promote the development of treatments for underserved patient populations. To be eligible for Orphan Drug designation, the treatment must target a disease that affects fewer than 200,000 new patients per year in the United States.

comments 0 comments - Posted May 7, 2010

April 2010

Insulin-Producing Cells Derived from Specially Bred Pigs

NEW YORK, April 27, 2010 - The Juvenile Diabetes Research Foundation announced today that it is partnering with Living Cell Technologies (LCT), a New Zealand-based biotechnology company focused on developing cell based therapeutics, in a Phase II clinical trial to study the safety and effectiveness of transplanting encapsulated insulin-producing cells from pigs as a treatment for type 1 diabetes with significant hypoglycemia unawareness.

comments 1 comment - Posted Apr 28, 2010

Nanoparticle Vaccine Stops the Progression of Type 1 Diabetes in Mice

Using a sophisticated nanotechnology-based "vaccine," researchers were able to successfully reverse type 1 diabetes in mice and slow the onset of the disease in mice at risk for the disease.  The study, co-funded by the Juvenile Diabetes Research Foundation, provides new and important insights into understanding how to stop the immune attack that causes type 1 diabetes, and could even have implications for other autoimmune diseases.

comments 2 comments - Posted Apr 9, 2010

February 2010

JDRF-Funded Research Advances Potential for Regeneration as a Possible Cure for Type 1 Diabetes

A hormone responsible for the body's stress response is also linked to the growth of insulin-producing cells in the pancreas, according to JDRF- funded researchers at the Salk Institute for Biological Studies in California. The findings are the latest advances to underscore the potential for regeneration as a key component of a possible cure for type 1 diabetes.

comments 2 comments - Posted Feb 22, 2010

November 2009

Endocrinologists Recommend Describing Dramatic Reversals of Diabetes Symptoms As

How careful should healthcare workers and patients be in describing a total remission of diabetes as a "cure?" That's a question that has taken on increasing urgency in the wake of reports about dramatic reversals of type 2 symptoms after gastric bypass surgery and the cessation of symptoms in people with type 1 diabetes after pancreatic islet replacement. To answer it, a group of endocrinologists met earlier this year to come up with descriptions and definitions that accurately describe what happens when people with diabetes experience a reversal of symptoms.

comments 2 comments - Posted Nov 14, 2009

August 2009

Scientists Find That a Single Gene Can Convert Pancreatic Alpha Cells Into Betas in Lab Mice

There's a gene whose name you should remember because it could mark a crucial point in the war on type 1 diabetes.

comments 3 comments - Posted Aug 13, 2009

March 2009

Teens Make A Difference For Diabetes

These amazing teens-selected from 20,000 entries nationwide-were named State Honorees (along with 102 other state winners throughout the U.S.) in the 14th annual Prudential Spirit of Community Awards, a national program honoring middle and high school students for their outstanding acts of volunteerism.  The program is conducted by Prudential Financial and the National Association of Secondary School Principals. Over the past 14 years, they have honored more than 80,000 young volunteers at the local, state, and national levels.

comments 1 comment - Posted Mar 17, 2009

At Last! Restrictions on Stem Cell Research Lifted

"Medical miracles do not happen simply by accident," said President Obama, as he signed an executive order lifting the ban on federally funded embryonic stem cell research. The Juvenile Diabetes Research Foundation (JDRF) is celebrating President Obama's new policy. They recently released this statement by Mary Tyler Moore, the International Chairman of the JDRF: 

comments 12 comments - Posted Mar 17, 2009

January 2009

Chicago Diabetes Project Collaborates Globally to Find the Cure

Nearly every time that I mention islet transplantation in a conversation about diabetes, the person I'm with responds with a sniff that it's never going to work because of the immune suppression problem.

comments 12 comments - Posted Jan 24, 2009

December 2008

Rethinking the Treatment of Diabetes

The first time I presented medical research findings, I was not yet a physician. The year was about 1975. I was in my early forties and a mid-career engineer. The forum was a scientific symposium on diabetes. At the time, I felt that I had discovered the holy grail of diabetes care and was eager to share what I had learned.

comments 22 comments - Posted Dec 8, 2008

Parents Of Son Who Died From Type 1 Complications Establish a Professorship in Diabetes Research
Parents Of Son Who Died From Type 1 Complications Establish a Professorship in Diabetes Research

I am always impressed when people find the strength to turn their own painful experience into a way to help others. In case you are losing faith that people are out there raising money, trying to find the Cure, and taking care of each on.

comments 1 comment - Posted Dec 8, 2008

September 2008

Co-Workers, Neighbors, and Families Form Teams to Raise Money to Fight Diabetes

To keep pace with the growing number of Americans with diabetes, the American Diabetes Association (ADA) invites communities nationwide to their brand new fundraising walk, Step Out: Walk to Fight Diabetes. 

comments 3 comments - Posted Sep 11, 2008

August 2008

Can Surgery Cure Type 2? Interesting Newsweek Article Examines Raging Pros and Cons

In March, Diabetes Health reported on Dr. Francesco Rubino, a surgeon who claims that the origin of diabetes is in the digestive system, not the gut, and that gastric bypass surgery cures type 2 diabetes.

comments 0 comments - Posted Aug 29, 2008

Beta Cells Morph into Stem-Like Cells: Can They Also Turn into Insulin Producers?
Beta Cells Morph into Stem-Like Cells: Can They Also Turn into Insulin Producers?

A study of beta cells at McGill University Health Centre in Montreal could hold significant promise for people with type 1 diabetes.

comments 0 comments - Posted Aug 5, 2008

June 2008

Study by 24 Doctors and Researchers Lobs Rebuttal At the ADA and EASD for Their Stance on Low-Carb
Study by 24 Doctors and Researchers Lobs Rebuttal At the ADA and EASD for Their Stance on Low-Carb

Twenty-four diabetes doctors and researchers from the United States, Canada, the United Kingdom, Finland, Sweden and Portugal have published a study criticizing the American Diabetes Association (ADA) assertion that diabetics should consume no fewer than 130 mg of carbohydrates daily and the European Association for the Study of Diabetes (EASD) statement that low-carb diets are “not justified.”

comments 28 comments - Posted Jun 26, 2008

This Week's Diabetes Research Highlights
This Week's Diabetes Research Highlights

Tekturna Reduces Kidney Disease Indicator

The blood pressure medicine Tekturna (aliskiren) may have a beneficial side effect for people with type 2 diabetes and high blood pressure who are at risk of kidney disease. According to a recent article in The New England Journal of Medicine, the drug reduces proteinuria, a key indicator of kidney disease, by 20 percent in patients with type 2 diabetes.

comments 2 comments - Posted Jun 26, 2008

Looking to Participate in a Clinical Trial? Here Are Some Good Sites to Explore
Looking to Participate in a Clinical Trial? Here Are Some Good Sites to Explore

Clinical trials have been a staple of diabetes research ever since 1922, when doctors in a Toronto hospital injected a young boy dying from the disease with pancreatic extracts. (The extracts contained the recently discovered hormone, insulin. The boy survived and lived another 13 years.)

comments 3 comments - Posted Jun 19, 2008

March 2008

The Cure: The Slow Road to Hope

Talk of a cure has been around forever. Sometimes it seems as if the cure is a constantly receding dream, always ten years away or just around the next corner.

comments 12 comments - Posted Mar 9, 2008

September 2007

Research, Rivalry, and Investing in the Cure
Research, Rivalry, and Investing in the Cure

Since the 1950s, the National Institutes of Health (NIH) has funded almost all diabetes research worldwide. From its headquarters in Bethesda, Maryland, the NIH oversees a $28 billion annual medical research budget. More than $1 billion of those taxpayer dollars go specifically toward diabetes research. Still, a cure remains frustratingly elusive.

comments 0 comments - Posted Sep 13, 2007

February 2007

Spring Point Project's Potential Diabetes Cure to Mark Another Major Milestone

MINNEAPOLIS, Minn. - For the millions of people worldwide who are afflicted with diabetes, we are now one step closer to a potential cure for the disease. Spring Point Project, a non-profit organization created to expedite the widespread availability of islet tissue for diabetes care, will open its first biosecure animal facility in Western Wisconsin in February to hold high-health pathogen-free pigs. Insulin-producing islet cells from pigs are needed to meet the demands that cannot be realized by using transplantation of human islets.

comments 0 comments - Posted Feb 28, 2007

June 2006

Cure Research Back in the News

Two and a half years ago, the journal Science published results from Denise Faustman’s groundbreaking study in which type 1 diabetes was reversed in non-obese diabetic mice injected with a combination of an immune adjuvant and spleen cells. Recently, researchers at the University of Chicago, Washington University in St. Louis and Harvard’s Joslin Clinic all partially replicated Dr. Faustman’s research.

comments 0 comments - Posted Jun 1, 2006

March 2004

The Latest Cure

In November 2003 the news was everywhere. “Juvenile diabetes cured in lab mice!” proclaimed the November 14, 2003, edition of The Boston Globe.

comments 6 comments - Posted Mar 1, 2004

June 2002

Hope for a Type 2 Cure

Researchers may have discovered a protein in the liver that could lead to a cure for type 2 diabetes, according to a new study published in the February 19, 2002, issue of Nature Genetics. Doctors at the Medical College of Ohio found that this protein, called CEACAM1, helps to clear insulin from the blood.

comments 0 comments - Posted Jun 1, 2002

December 2001

The Diabetes Cure of Tomorrow

Someday, a cure for diabetes will be found. But the question still remains about it how it will happen. By regenerating our own cells? Or maybe by transplanting islets from pigs into humans?

comments 0 comments - Posted Dec 1, 2001

September 2001

Type 1 Diabetes Cured Mice

A 40-day treatment of type 1 diabetes was shown to cure the disease in mice, say researchers from Massachusetts. The encouraging results could lead to finding a cure for diabetes in humans, they say.

comments 0 comments - Posted Sep 1, 2001

September 2000

President Clinton Announces 10 New Transplant Sites - Revolutionary New Islet-transplant Procedure to Begin This Fall

On July 13, President Clinton announced the 10 centers chosen to replicate the Edmonton Protocol.

comments 0 comments - Posted Sep 1, 2000

November 1992

Is Fetal Tissue the Answer for Finding a

Fetal tissue. No other topic in diabetes research is as emotionally stirring. Some say that fetal tissue is the key to progress, and perhaps that fetal tissue will even cure diabetes. Others claim that fetal tissue research is immoral because it produces an incentive for abortions. How important is fetal tissue research? Is it likely to produce a cure for diabetes? Are there alternatives that avoid ethical concerns?

comments 0 comments - Posted Nov 1, 1992

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