Scientists generally think that decreased insulin production by the pancreas, a hallmark of type 2 diabetes, is due to the death of the organ's beta cells. However, scientists at Columbia University Medical Center report that the beta cells do not die, but instead revert to a more basic cell type.
Physically fit men with type 2 diabetes and a heart condition known as left ventricular hypertrophy run a considerably lower risk of premature death than their diabetic peers who are not fit. That's the conclusion of a longitudinal study of 866 patients conducted by Veterans Affairs Medical Center and George Washington University, Washington, DC.
Endocrinologist Robert Cuddihy, MD, joined Sanofi US over a year ago to be the company’s Vice President and Medical Diabetes Head in the United States. He is responsible for developing and executing the US strategy for Sanofi’s Diabetes Division, including pharmaceuticals, devices, and other technologies. He previously served as the medical director for several organizations, including the International Diabetes Center-Park Nicollet in Minnesota.
Swedish researchers report that a drop in A1C of less than one percentage point can lower the risk of death from cardiovascular disease among people with diabetes by nearly half. Specifically, they found that patients who reduced their A1C from 7.8% to 7.0% decreased their risk of dying from cardiovascular disease by 45 percent.
Bariatric surgery, which alters or blocks portions of the digestive system, has produced long-term remission of diabetes symptoms in many type 2 patients. However, a small study of obese type 2 patients who underwent bariatric surgery shows that the longer they had diabetes, the greater the chances that their disease recurred after surgery. The retrospective study, conducted by Yessica Ramos, MD, at the Mayo Clinic Arizona, found that patients who had had diabetes for five years or longer were nearly four times as likely to experience a recurrence of the disease after the remission brought on by the surgery.
Diabetes affects nearly 25 million Americans, and that number is expected to grow substantially every year. It's the fifth leading cause of death in America, more than breast cancer and AIDs combined. And according to a report released last week from the Agency for Healthcare Research and Quality (AHRQ), it's a disease that’s costing Americans $83 billion a year in hospital fees — 23 percent of total hospital spending.
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