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One of the major complications of diabetes is diabetic nephropathy, a loss of kidney function that may lead to renal failure. As kidney disease progresses, the barrier that keeps large molecules out of the urine, called the glomerular barrier, begins to break down. With the barrier failing, certain large molecules begin to migrate into the urine. One of those hefty molecules is immunoglobulin M, or IgM.
1 comment - Aug 19, 2009 -
The theory of unintended consequences has gotten another boost. Although two drugs designed to slow the loss of kidney function in people with type 1 diabetes turned out to be busts, they had a wonderful but entirely unexpected side effect: Eye damage was reduced by 65 to 70 percent in the patients taking them.
6 comments - Aug 17, 2009 -
A report commissioned by the U.S. Centers for Disease Control and Prevention (CDC) is being published in this month's issue of the American Journal of Kidney Diseases, the National Kidney Foundation's journal. Led by kidney specialists Dr. Andrew S. Levey at Tufts Medical Center in Boston, Massachusetts, and Dr. William McClellan at Emory University in Atlanta, Georgia, the panel of experts designed a comprehensive public health strategy to prevent the development and complications of chronic kidney disease in the U.S.
1 comment - Mar 19, 2009 -
In what is believed to be a first-ever procedure, surgeons at Johns Hopkins have successfully removed a healthy donor kidney through a small incision in the back of the donor's vagina.
0 comments - Feb 17, 2009 -
Utah Jazz owner, Larry H. Miller had his legs amputated six inches below the knee last week. A spokesman for the successful pro basketball team told the Associated Press that the surgery was due to complications from type 2 diabetes. The spokesman noted that Miller was already using a wheelchair before the surgery. Miller is 64 years old.
5 comments - Jan 26, 2009 -
Researchers at the Chinese University of Hong Kong report that having metabolic syndrome may raise the risk of chronic kidney disease in people with type 2 diabetes.
1 comment - Jan 6, 2009 -
The day I heard "Diabetes is not the leading cause of heart attack, blindness, kidney disease, and amputation," my life changed. I had believed the opposite to be true for the 32 years I'd been dealing with diabetes. Complications had always hung like a knife over my head.
14 comments - Dec 22, 2008 -
The first time I presented medical research findings, I was not yet a physician. The year was about 1975. I was in my early forties and a mid-career engineer. The forum was a scientific symposium on diabetes. At the time, I felt that I had discovered the holy grail of diabetes care and was eager to share what I had learned.
22 comments - Dec 8, 2008 -
Pentoxifylline, a drug used to treat patients with circulation problems, may also benefit those with kidney disease caused by diabetes and other conditions. Specifically, pentoxifylline decreases proteinuria, the abnormal leakage of protein into the urine, according to two articles in the September issue of the American Journal of Kidney Diseases, the official journal of the National Kidney Foundation.
0 comments - Oct 27, 2008 -
Last week was Kidney Disease Awareness and Education Week. Kidney disease is considered a "quiet disease," and many people don't recognize its early warning signs.
2 comments - Aug 20, 2008 -
Diabetes Health is the essential resource for people living with diabetes- both newly diagnosed and experienced as well as the professionals who care for them. We provide balanced expert news and information on living healthfully with diabetes. Each issue includes cutting-edge editorial coverage of new products, research, treatment options, and meaningful lifestyle issues.