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Endocrinology Archives

Endocrinology

Updated 139 weeks ago
Metformin Helped My Type 1 Diabetes

My name is Katherine Marple, and I've had type 1 diabetes for 13 years. I'm the first in my family to have the disease, so I've done most of the research and made most of the discoveries on my own. One of those discoveries was the power of metformin (in addition to insulin) to help me control my diabetes.

Comments 16 comments - Aug 18, 2011 - * * * * *

New Website Facilitates Communication Between Type 2 Patients and Their Physicians

People with type 2 diabetes often find visits with their physicians frustrating.  Dr. Jeffrey Mechanick, MD, FACE, FACP, Secretary of the American Association of Clinical Endocrinologists (AACE), observes, "Many times when patients come to the doctor, the first thing that they say is really what's on their mind--that's their top priority. But oftentimes physicians don't address that at all. Instead, they move on to what's on their own agenda."

Comments 3 comments - Jul 31, 2011 - * * * * *

Be Thankful: A Letter of Gratitude

If you, like me, have diabetes, you realize upon reflection that you are, despite the constant demands of the disease, blessed.  Somewhere, sometime, you have benefited from the kindness, professionalism, and genuine concern of a medical professional, be it a nurse, pharmacist, dietitian, physician, therapist, or supporting staff.   

Comments 7 comments - Apr 7, 2011 - * * * * *

Does Coffee Protect Against Type 2 Diabetes?

Folks who need that morning cup of coffee to get going may be protecting themselves from type 2 diabetes, a new study suggests. UCLA researchers wrote in the journal Diabetes last month that drinking four cups of coffee a day reduced women's chance of developing type 2 by a bit less than half. What's more, the scientists point to a specific reason why all that java has a beneficial effect: a protein known as sex hormone-binding globulin (SHBG). Scientists have suspected for some time that SHBG was connected to diabetes development.

Comments 0 comments - Feb 19, 2011 - * * * * *

Mouse Study Eliminates Need for Insulin by Eliminating Glucagon

Can't make insulin? That might not be a problem, according to Dr. Roger Unger, the lead researcher on a mouse study out of UT Southwestern Medical Center. As Dr. Unger stated in a press release, his findings "suggest that if there is no glucagon, it doesn't matter if you don't have insulin....In adulthood, at least with respect to glucose metabolism, the role of insulin is to control glucagon. And if you don't have glucagon, then you don't need insulin...If diabetes is defined as restoration of glucose homeostasis to normal, then this treatment can perhaps be considered very close to a ‘cure.' "

Comments 1 comment - Feb 16, 2011 - * * * * *

Last Patient Completes the EU Phase III Study of Diamyd® Antigen Based Therapy for Type 1 Diabetes

The final patient has performed the last visit of the main study period in Diamyd Medical's European Phase III study. Treatment with the antigen based therapy Diamyd® is made to investigate whether beta cell function and thereby blood sugar control can be preserved in children and adolescents with new onset type 1 diabetes. The top line results from this study are expected to be reported as planned, in late spring 2011.

Comments 0 comments - Feb 15, 2011 - * * * * *

Type 1 Diabetes Associated With Common Cold Virus

It's generally thought that a genetic predisposition to type 1 diabetes is not enough to develop the disease, but that an environmental trigger is required to activate it. Researchers are not sure what that environmental trigger is, but enteroviruses have been under suspicion for quite a while. Enteroviruses are the second leading cause of viral colds in children.

Comments 1 comment - Feb 8, 2011 - * * * * *

"The Hormone of Darkness" Won't Come Out in the Light

Keeping the lights on all night might keep away the monsters under the bed, but it also keeps away the "hormone of darkness," melatonin, according to a new study in the Journal of Clinical Endocrinology and Metabolism. Melatonin, which is secreted into the blood by the brain's pineal gland at night, is involved in the circadian rhythm. Scientists believe that disrupting circadian rhythms can contribute to metabolic disease. Specifically, melatonin receptor genes have been linked to type 2 diabetes. Melatonin is also a powerful antioxidant that may help prevent cancer.

Comments 3 comments - Jan 19, 2011 - * * * * *

Stem cells used to make pancreas, gut cells

(Reuters) - Stem cells can be transformed into the pancreatic cells needed to treat diabetes and into complex layers of intestinal tissue, scientists demonstrated in two experiments reported on Sunday.

Comments 6 comments - Dec 13, 2010 - * * * * *

Surgeons Create Functional Artificial Pancreatic Tissue

In a proof-of-concept study presented at the 2010 Annual Clinical Congress of the American College of Surgeons, the researchers note that the matrix not only helps to understand the micro-architecture of the pancreas, but also prolongs the survival and preserves the function of the islets. Islets survived longer in the bio-artificial matrix than in conventional transplantation sites, and they produced significantly more insulin when challenged with glucose.

Comments 0 comments - Oct 30, 2010 - * * * * *

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