People with type 2 diabetes often find visits with their physicians frustrating. Dr. Jeffrey Mechanick, MD, FACE, FACP, Secretary of the American Association of Clinical Endocrinologists (AACE), observes, "Many times when patients come to the doctor, the first thing that they say is really what's on their mind--that's their top priority. But oftentimes physicians don't address that at all. Instead, they move on to what's on their own agenda."
If you, like me, have diabetes, you realize upon reflection that you are, despite the constant demands of the disease, blessed. Somewhere, sometime, you have benefited from the kindness, professionalism, and genuine concern of a medical professional, be it a nurse, pharmacist, dietitian, physician, therapist, or supporting staff.
Can't make insulin? That might not be a problem, according to Dr. Roger Unger, the lead researcher on a mouse study out of UT Southwestern Medical Center. As Dr. Unger stated in a press release, his findings "suggest that if there is no glucagon, it doesn't matter if you don't have insulin....In adulthood, at least with respect to glucose metabolism, the role of insulin is to control glucagon. And if you don't have glucagon, then you don't need insulin...If diabetes is defined as restoration of glucose homeostasis to normal, then this treatment can perhaps be considered very close to a ‘cure.' "
The final patient has performed the last visit of the main study period in Diamyd Medical's European Phase III study. Treatment with the antigen based therapy Diamyd® is made to investigate whether beta cell function and thereby blood sugar control can be preserved in children and adolescents with new onset type 1 diabetes. The top line results from this study are expected to be reported as planned, in late spring 2011.
It's generally thought that a genetic predisposition to type 1 diabetes is not enough to develop the disease, but that an environmental trigger is required to activate it. Researchers are not sure what that environmental trigger is, but enteroviruses have been under suspicion for quite a while. Enteroviruses are the second leading cause of viral colds in children.
(Reuters) - Stem cells can be transformed into the pancreatic cells needed to treat diabetes and into complex layers of intestinal tissue, scientists demonstrated in two experiments reported on Sunday.
In a proof-of-concept study presented at the 2010 Annual Clinical Congress of the American College of Surgeons, the researchers note that the matrix not only helps to understand the micro-architecture of the pancreas, but also prolongs the survival and preserves the function of the islets. Islets survived longer in the bio-artificial matrix than in conventional transplantation sites, and they produced significantly more insulin when challenged with glucose.
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