Two Asian companies--BioLineRx of Israel and JHL Biotech of Taiwan--have agreed to collaborate on the development and marketing of BL-9020, a monoclonal antibody that could become a significant means of treatment for early-stage type 1 diabetes.
People with type 2 diabetes and those heading toward that diagnosis may face a quicker decline in their beta cell function than previously understood, according to a new study published in the Journal of Clinical Endocrinology & Metabolism. That means the progress and challenges for such patients may progress more quickly than doctors expects and need more aggressive treatment.
Type 1 diabetes doesn't happen all at once. Scientists have shown that it's usually a gradual process, in which the insulin-producing beta cells eventually fade out. So wouldn't it be marvelous if the function of those beta cells could be preserved, allowing people newly diagnosed with diabetes to produce some of their own insulin for a longer time?
Low doses of metformin and rosiglitazone seem to delay the onset of type 2 in prediabetic people who have impaired glucose tolerance, according to a Canadian study. However, although the drug combination was effective over the first year of the study in helping to control glucose levels and insulin resistance, it was not effective subsequently in delaying the onset of insulin resistance and pancreatic beta cell deterioration.
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