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Diabetes and Beta Cells

Page 2
Type 2 Diabetes: From Old Dogmas to New Realities

Over the last decade, dramatic changes have occurred in our understanding of the onset and progression of prediabetes. Lightning speed changes have also occurred regarding the therapies available to achieve optimal blood glucose control. Even with all of this change, however, many old dogmas hang on. It's time to become aware of the new realities.  In this article, I focus on two common old dogmas and the new realities.

Comments 2 comments - Jun 16, 2011 - * * * * *

Store Your Teeth in a Stem Cell Bank

Every year four million baby teeth fall out, and 1.4 million wisdom teeth are pulled out of our collective mouth. Until recently, the only entity really interested in all those teeth was the tooth fairy. But all that changed in the year 2000, with the discovery that dental pulp contains adult stem cells. In the not-too-distant future, those stem cells might be used for growing new islet cells to cure diabetes. The problem is, how to keep the teeth nice and fresh until that hoped-for day. That's where Provia Laboratories comes in, with their Store-A-Tooth service.

Comments 1 comment - Apr 24, 2011 - * * * * *

Pre-Diabetes Glossary

This List defines terms that people with prediabetes commonly encounter as they learn more about the condition.

Comments 2 comments - Mar 29, 2011 - * * * * *

Last Patient Completes the EU Phase III Study of Diamyd® Antigen Based Therapy for Type 1 Diabetes

The final patient has performed the last visit of the main study period in Diamyd Medical's European Phase III study. Treatment with the antigen based therapy Diamyd® is made to investigate whether beta cell function and thereby blood sugar control can be preserved in children and adolescents with new onset type 1 diabetes. The top line results from this study are expected to be reported as planned, in late spring 2011.

Comments 0 comments - Feb 15, 2011 - * * * * *

Lilly and the JDRF Partner to Fund Regenerative Medicine Research in Type 1 Diabetes

INDIANAPOLIS and NEW YORK - Eli Lilly and Company and the Juvenile Diabetes Research Foundation (JDRF) today announced that they have signed an agreement to fund early-stage research that could enable patients with type 1 diabetes to regenerate insulin-producing cells destroyed by the disease.

Comments 0 comments - Feb 4, 2011 - * * * * *

Stem cells used to make pancreas, gut cells

(Reuters) - Stem cells can be transformed into the pancreatic cells needed to treat diabetes and into complex layers of intestinal tissue, scientists demonstrated in two experiments reported on Sunday.

Comments 6 comments - Dec 13, 2010 - * * * * *

The Sanford Project Launches Research Study to Find a Cure

"The objective of this clinical trial (research study) is to determine if the medications can rescue the few beta cells that remain soon after the diagnosis of type 1 diabetes; and whether new beta cells can even be regenerated," commented Alex Rabinovitch, MD, Principal Investigator of the trial and Associate Director of The Sanford Project. "The investigational combinations of these medications could possibly allow patients to decrease or no longer need to inject insulin to keep their blood levels under proper control."

Comments 0 comments - Aug 12, 2010 - * * * * *

Malfunctioning Pancreatic

A malfunction in the pancreas's "circadian clock*," the built-in timer found in all living things that regulates major biological processes, may be one of the reasons that people develop diabetes.

Comments 0 comments - Jun 29, 2010 - * * * * *

Beware the Perils of Severe Hypoglycemia

Over 80 years ago, famed diabetologist Elliot Joslin said about the treatment of patients with type 1 diabetes: "Ketoacidosis may kill a patient, but frequent hypoglycemic reactions will ruin him."  Unfortunately, hypoglycemia continues to be the most difficult problem facing most patients, families, and caregivers who deal with the management of type 1 diabetes on a daily basis. Frequent hypoglycemia episodes not only can "ruin," or adversely impact the quality of life for patients, but also, when severe, can cause seizures, coma, and even death.

Comments 12 comments - May 13, 2010 - * * * * *

Recruiting Patients with Newly Diagnosed Type 1 Diabetes

Dr. Richard Hays announced today that he is now recruiting children with newly diagnosed type 1 diabetes for Protégé Encore, a randomized, placebo-controlled Phase III clinical trial. This is the second of two Phase III studies testing the safety and efficacy of an investigational drug called teplizumab. The first study, known as Protégé, has completed enrollment of more than 530 subjects with type 1 diabetes. There is currently no approved therapy to slow the progression of type 1 diabetes.

Comments 0 comments - May 12, 2010 - * * * * *

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