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Beta Cells Archives

Diabetes and Beta Cells

Page 3
Researchers Discover Protein that Triggers Islet Cell Rejection

Researchers at RIKEN and Fukuoka University have pinpointed the mechanism responsible for early rejection of transplanted pancreatic islet cells in the treatment of type 1 diabetes. A new system based on this mechanism has been shown to vastly increase transplant efficiency, setting the stage for the development of powerful new treatment techniques.

Comments 0 comments - Feb 9, 2010 - * * * * *

Skin cells transformed directly into nerve cells: Are beta cells next?

WASHINGTON (Reuters) - Researchers have transformed ordinary mouse skin cells directly into neurons, bypassing the need for stem cells or even stemlike cells and greatly speeding up the field of regenerative medicine.

Comments 0 comments - Jan 29, 2010 - * * * * *

Newly identified genes influence insulin and glucose regulation

An international research consortium has found 13 new genetic variants that influence blood glucose regulation, insulin resistance, and the function of insulin-secreting beta cells in populations of European descent. Five of the newly discovered variants increase the risk of developing type 2 diabetes, the most common form of diabetes.

Comments 0 comments - Jan 23, 2010 - * * * * *

Relieving Stress on Insulin-Producing Cells May Prevent Diabetes

BOSTON, Mass. - Dec. 23, 2009 - Cells in your body are constantly churning out poisonous forms of oxygen (oxidants) and mopping them up with a countervailing force of proteins and chemicals (anti-oxidants). This balancing act of oxidative stress is particularly likely to go haywire in beta cells, the insulin-producing cells that malfunction and then start to die off in type 2 diabetes.

Comments 0 comments - Dec 29, 2009 - * * * * *

Cancer Drug May Slow Body's Rejection of Beta Cells in Type 1

Rituxamab, a drug that treats lymphoma and rheumatoid arthritis, may soon be used to help combat the destruction of pancreatic beta cells in newly diagnosed cases of type 1 diabetes. Researchers at Indiana University have found that the drug, originally developed and sold by Genentech as Rituxan, temporarily slows or stops the destruction of the 10 or 20 percent of beta cells that type 1s typically have remaining when they are first diagnosed.

Comments 0 comments - Dec 21, 2009 - * * * * *

JDRF Announces Diabetes Research Program with Johnson & Johnson

NEW YORK, Dec. 17, 2009 - The Juvenile Diabetes Research Foundation, a leader in setting the agenda for diabetes research worldwide, said today that it will begin working with The Johnson & Johnson Corporate Office of Science and Technology, and its affiliates, to speed the development of drug targets and pathways to promote the survival and function of insulin-producing cells in people who have diabetes.  The program will look to fund research at academic centers around the world that could eventually lead to novel drug targets and industry collaborations for the treatment of type 1 diabetes.

Comments 0 comments - Dec 19, 2009 - * * * * *

Airman Injured in Afghanistan Receives Unprecedented Islet Cell Transplant

WASHINGTON, Dec. 15 /PRNewswire-USNewswire/ -- A 21-year old Airman severely wounded in Afghanistan is recovering at Walter Reed Army Medical Center after several surgeries and an unprecedented transplant.

Comments 0 comments - Dec 17, 2009 - * * * * *

Promising Pancreate Creates New Islets

One thing that really frustrates people with diabetes mellitus is the biopharma industry's focus on treatments rather than cures. A cure is what the diabetes community wants, not another band-aid. So the existence of a biopharma company that calls itself "CureDM" is promising, and its first product, Pancreate, seems to be on its way to fulfilling that promise.

Comments 0 comments - Sep 28, 2009 - * * * * *

Diabetes in a Dish: Steps Toward a Cure

By reprogramming skin cells from people with type 1 diabetes, scientists have produced beta cells that secrete insulin in response to changes in glucose levels. Dr. Douglas Melton and his colleagues at the Harvard Stem Cell Institute started by using the skin cells to generate induced pluripotent stem (iPS) cells. Once they had iPS cells, the researchers manipulated them into developing into pancreatic islet (beta) cells.

Comments 0 comments - Sep 19, 2009 - * * * * *

To be or not to be... a pancreatic beta cell

Our genes are like a recipe for a human. It's a very complicated recipe, determining how much of this protein and how much of that enzyme need to be added into the mix in order for us to function properly, but our genes are pretty good at getting it right. Although we are still learning how the recipe works, what ingredients (gene products) are involved, and when are they are produced, our knowledge is growing fast.  

Comments 0 comments - Aug 28, 2009 - * * * * *

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