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Health Research Archives

Health Research

Page 5
FDA Freezes Long-Term Study on Diabetes Drug Avandia

A long-term study on the safety of a popular diabetes drug was put on hold Wednesday by the Food and Drug Administration, while the FDA considers whether it's too dangerous to continue.  Several large studies have linked the drug, Avandia, to a higher risk of heart attacks and other heart problems. While other studies have not found the same risk, last week an FDA advisory panel recommended that the drug not be sold without a stronger warning label or possibly limits on who could receive it.

Comments 0 comments - Jul 23, 2010 - * * * * *

Hepatitis C and Insulin Resistance

We have known for several years that Hepatitis C, a common cause of liver cirrhosis and cancer, also makes people three to four times more likely to develop Type 2 diabetes. In studying the insulin resistance of 29 people with Hepatitis C, Australian researchers have confirmed that they have high insulin resistance, a precursor to diabetes. However, almost all insulin resistance occurs in muscle, with little or none in the liver, a very surprising finding given that Hepatitis C is a liver disease.

Comments 0 comments - Jul 21, 2010 - * * * * *

Moderate Alcohol Intake Lessens Chance of Developing Type 2, Says Dutch Study

While teetotaling is the surest way to avoid abusing alcohol, it turns out that moderate alcohol intake may be one way to stave off the development of type 2 diabetes.

Comments 0 comments - Jul 16, 2010 - * * * * *

Avandia and the FDA Panel: Scientific Leaders Urge Diabetes Patients to Talk with their Doctor before Making Changes to their Medication Use

The U.S. Food and Drug Administration's (FDA) Joint Meeting of the Endocrinologic and Metabolic Drugs Advisory Committee and Drug Safety and Risk Management Advisory Committee has completed their evaluation of the scientific research available on the safety of rosiglitazone. The deliberations of the panel reflected the complexity of the issues, with several members voting to add additional warnings or to withdraw the drug from the U.S. market. Ultimately, the final recommendation was to allow Avandia to remain on the market. Now that the expert panel has concluded its meeting, the FDA will review their recommendations and make the final decision on whether the drug remains available to patients.

Comments 0 comments - Jul 15, 2010 - * * * * *

Johns Hopkins Team Discovers Sweet Way to Detect Pre-Diabetes

Having discovered a dramatic increase of an easy-to-detect enzyme in the red blood cells of people with diabetes and pre-diabetes, Johns Hopkins scientists say the discovery could lead to a simple, routine test for detecting the subtle onset of the disease, before symptoms or complications occur and in time to reverse its course.

Comments 0 comments - Jul 15, 2010 - * * * * *

Testosterone Gel in Older Men Leads to Increased Cardiovascular Problems

A clinical trial that used testosterone gel, a topically applied ointment, to increase muscle strength in older men with low testosterone levels was stopped because adverse cardiovascular events increased significantly among patients receiving the treatment.

Comments 0 comments - Jul 7, 2010 - * * * * *

More from ACCORD

In people with longstanding type 2 diabetes who are at high risk for heart attack and stroke, lowering blood sugar to near-normal levels did not delay the combined risk of diabetic damage to kidneys, eyes, or nerves, but did delay several other signs of diabetic damage, a study has found. The intensive glucose treatment was compared with standard glucose control.

Comments 0 comments - Jul 2, 2010 - * * * * *

Do You Have Obstructive Sleep Apnea?

It raises fasting blood sugars. It increases the risk for type 2 diabetes. Millions of people suffer from it. And many don't even know they have it.

Comments 1 comment - Jun 30, 2010 - * * * * *

Malfunctioning Pancreatic

A malfunction in the pancreas's "circadian clock*," the built-in timer found in all living things that regulates major biological processes, may be one of the reasons that people develop diabetes.

Comments 0 comments - Jun 29, 2010 - * * * * *

Scientists Have Found the Peptide Trigger for Type 1 Diabetes in Animal Tests

Researchers from the National Jewish Health and University of Colorado Anschutz Medical Campus have found a specific protein fragment, or peptide, that stimulates an immune system attack resulting in diabetes. Their experiments in mice contradict conventional wisdom about such peptides and support work by scientists studying autoimmune diseases.

Comments 0 comments - Jun 24, 2010 - * * * * *

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