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Page 4
Interpreting Your C-peptide Values

Normal C-peptide levels for a fasting test are generally considered to be anything between 0.5 nanograms (ng) per millileter (ml) and 3 ng/ml, although people who do not have diabetes may occasionally stray out of this range. The following is a range of C-peptide values in people without diabetes, as compiled by Endocrine Sciences, Inc., a California-based laboratory that conducts the test. It should be noted that, in some cases, subjects fell below the normal range of C-peptide values, but were still not found to have diabetes. The range of values may also vary according to what lab your health care practitioner uses.

Comments 11 comments - Sep 1, 2000 - * * * * *

What is the C-peptide Test?

The precursor to insulin produced by the pancreas's beta cells is a peptide chain known as proinsulin. Made up of amino acids bound into a u-shape by a connecting polypeptide, proinsulin is stored in beta cells until a glucose load demands the release of insulin. At this point, the connecting molecule is broken off the bottom of the "u"-its shape earning it the moniker C-peptide-freeing the insulin molecule for secretion.

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An Old Test Teaches Doctors New Tricks: C-peptide Exam Becoming an Accepted Tool for Diabetes Treatment

If you're a person with diabetes who suspects your beta cells may still be hard at work, you may be more right than you know. Most people with diabetes, including type 1s, are still producing at least trace amounts of insulin. And while BGs and HbA1cs may be the foundation for any good diabetes treatment, when it comes to showing insulin production, they don't necessarily paint the full picture.

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