I have read with interest the promising information about youngsters and even adults who show a mutation in Kir6.2 gene causing neonatal type 1 diabetes and getting improvement with Sulfonylurea even though it is generally prescribed for type 2 diabetes. I have searched the net for any information that would indicate this special type of diabetes is actually at caused at ages older than birth to 6 months, but find very little. Is there any indication that it may also happen to children who are say 6-18 months of age at onset?
I would be very interested in knowing if this was possible. Also what type of genetic test is done to determine the mutation for this specific type of diabetes.
Anyone who has information on this please advise. I have an adult son who developed type 1 diabetes at age 13 months. He is now 32 years old on an insulin pump but shows insulin resistance and has complications, including diabetic retinopathy, weight gain and periphreal nueropathy.
Thanks
Tom Gleeson
Mr. Gleeson:
The following is from the www.monogenicdiabetes.org website:
"The University of Chicago's Kovler Diabetes Center has established a National Registry for Neonatal Diabetes with JDRF support. Inquiries should be directed to Dr. Lou Philipson at l-philipson@uchicago.edu. The Center's investigators not only study such forms of diabetes as MODY, PND, and TND, but also provide genetic testing, support, and information to patients and physicians in the U.S."
Perhaps they might be able to assist you with your son's case.
God Bless,
John |