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Smoking Induces Insulin Resistance

Jan 1, 1993

Researchers from the Institute of Medicine, Sahlgrenska Hospital, in Gøteborg, Sweden, have concluded that smoking causes insulin resistance.

After one night's fasting, a sample group of habitual smokers were given a subcutaneous injection of short acting insulin. Each subject was randomly selected to smoke one cigarette or abstain from tobacco entirely for several hours. The metabolic effect of the insulin was then evaluated.

A reduced glucose need of 12% was found for the smokers, when compared to the non-smokers, and the smokers showed a lower glucose infusion rate.

Insulin-antagonistic hormone GH was found to significantly increase during smoking, leading the researchers to conclude that smoking induces a notable resistance to insulin.


Categories: Insulin, Insulin Resistance, Research, Smoking



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