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In a study conducted at the Northeastern Ohio University Medical College, the effect of aspartame (Nutrasweet) on patients with a history of depression was measured.
The study examined the difference in response between subjects who received 30 mg of aspartame per kilogram of body weight per day, and those who received a placebo. Due to the severe, adverse reactions observed in response to consumption of aspartame, the Institutional Review Board forced the study to end prematurely (Biological Psychiatry, July, 1993).
[Advisory Board Comment: I think it should be mentioned that NutraSweet is far more beneficial than detrimental to most people with diabetes. - Nancy Bohannon, MD]
Categories: Depression, Diabetes, Sugar & Sweeteners
Diabetes Health is the essential resource for people living with diabetes- both newly diagnosed and experienced as well as the professionals who care for them. We provide balanced expert news and information on living healthfully with diabetes. Each issue includes cutting-edge editorial coverage of new products, research, treatment options, and meaningful lifestyle issues.

Comments
30 mg of aspartame per kg of body weight works out, in my case (90 kg) to 2,700 mg a day. That is roughly 335 aspartame "tablets" a day. Since this is several orders of magnitudes greater than any level I will ever take, I don't see the value in this study. Surely similar doses of other everyday foods, such as salt or sugar, would be far more damaging to one's health, wouldn't they?
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