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New Drug For Type 2: Precose Gets FDA OK
Precose, a new oral drug from Bayer, was recently granted market clearance by the FDA for the treatment of type 2 diabetes.
Precose, also called acarbose, works differently than current drugs. By slowing the digestion of carbohydrates in the small intestine, Precose decreases the rise in blood sugar that typically occurs after eating. As a result, the drug allows the body's own insulin to better regulate blood glucose levels.
"When diet and exercise fail, Precose can be an ideal treatment for patients with type 2 diabetes," says Harold Lebovitz, MD, Professor of Medicine at SUNY Downstate Medical Center, Brooklyn, N.Y. "Precose significantly reduces after-meal glucose levels. In addition, unlike sulfonylurea drugs, Precose does not cause hypoglycemia, hyperinsu-linemia, or weight gain."
According to Bayer, side effects of the drug "tend to be gastrointestinal in nature, such as flatulence, abdominal distention, and diarrhea due to fermentation of undigested carbohydrates. However, these symptoms have been moderate and generally diminish over time."
Says Frank Vinicor, MD, MPH, President of the ADA, "Type 2 diabetes is a serious, complex disease best managed through an individualized treatment plan. Acarbose offers physicians and the diabetes healthcare team a new tool in determining the best course of treatment for people with type 2 diabetes and for helping them achieve glycemic control."
Precose has been available for over four years in Europe under the brand name Glucobay.
Mean Change in HbA1c in Fixed Dose Monotherapy Studies
Dose of Precose}Change in HbA1c
(three times per day)
}25 mg }decreased 0.44
}50 mg }decreased 0.77
}100 mg }decreased 0.74
Doses in excess of 100 mg three times per day are not recommended
Categories: A1c Test, Blood Glucose, Blood Sugar, Diabetes, Government & Policy, Insulin, Low Blood Sugar, Medications, Type 2 Issues, Type 2 Medications
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Nov 1, 1995
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Diabetes Health
Diabetes Health is the essential resource for people living with diabetes- both newly diagnosed and experienced as well as the professionals who care for them. We provide balanced expert news and information on living healthfully with diabetes. Each issue includes cutting-edge editorial coverage of new products, research, treatment options, and meaningful lifestyle issues.
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Topics
- Diabetic / Diabetes Health
- Type 1 / 1.5 Diabetes
- Type 2 Diabetes
- Blood Glucose / Sugar
- High/Low Blood Sugar / Fast Acting Glucose
- Insulin- Pumps, Pens & Syringes
- Continuous Glucose Monitors, CGM, Infusion Sets
- Type 2 Medications
- Hyperglycemia
- Hypoglycemia
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