Home
You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View
See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.
Latest Diabetes Articles
Popular Diabetes Articles
Highly Recommended Diabetes Articles
The One-Two Combination
Abstract #134
Metformin 3D model.
Metformin and troglitazone were both shown to improve glycemic control of type 2 diabetes. In addition, using them in combination proved to be safe and to provide additional benefit.
Two weeks after test subjects were taken off their anti-diabetic therapy (mostly sulfonylureas) they were put on metformin or troglitazone for three months (monotherapy).
After three months the subjects taking metformin had troglitazone added to their therapy (MET-TGZ), and the subjects taking troglitazone had metformin added (TGZ-MET). This combined therapy lasted for three more months. No significant side-effects or adverse effects were seen when the drugs were used in combination.
After three months of monotherapy, both groups experienced improved fasting blood sugars (FBS) levels. Metformin lowered FBS by 19 percent, and troglitazone lowered FBS by 17 percent. BG levels after a meal were also improved. BG response to a meal was decreased by 62 percent for patients on metformin and by 56 percent for patients taking troglitazone.
After three months of combined therapy, subjects experienced even more decreases in FBS. The MET-TGZ group's FBS dropped (from baseline) 32 percent and the TGZ-MET group's dropped 42 percent. In addition, HbA1c levels dropped 13.2 percent in the MET-TGZ group and 16 percent in the TGZ-MET group compared to HbA1cs on prior therapy.
Categories: A1c Test, Blood Sugar, Diabetes, Metformin, Professional Issues, Type 2 Issues
You May Also Be Interested In...
Click Here To View Or Post Comments
0 comments -
Aug 1, 1997
-
Diabetes Health
Diabetes Health is the essential resource for people living with diabetes- both newly diagnosed and experienced as well as the professionals who care for them. We provide balanced expert news and information on living healthfully with diabetes. Each issue includes cutting-edge editorial coverage of new products, research, treatment options, and meaningful lifestyle issues.
-
Topics
- Diabetic / Diabetes Health
- Type 1 / 1.5 Diabetes
- Type 2 Diabetes
- Blood Glucose / Sugar
- High/Low Blood Sugar / Fast Acting Glucose
- Insulin- Pumps, Pens & Syringes
- Continuous Glucose Monitors, CGM, Infusion Sets
- Type 2 Medications
- Hyperglycemia
- Hypoglycemia
Email to a Friend
Send a link to this page to your friends and colleagues.