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Islet Capsule Lowers Blood Sugar Levels in Diabetic Rats
Researchers at Kyoto University in Japan have discovered a technique in which a capsule containing pancreatic cells can be implanted into a patient with a minor case of diabetes.
In preliminary trials, pancreatic cells from a donor's pancreas were implanted in the backs of five rats who suffered from diabetes. According to a recent issue of The Daily Yomiuri, the rats all demonstrated normal blood sugar levels for up to 80 days after taking the capsule.
The islets are enclosed in a 4.5-cubic-centimeter capsule, which could be implanted into a human being's lower abdomen or thigh. According to Professor Kazutomo Inoue of the University Institute for Frontier Medical Science, the transplanted cells are expected to secrete insulin through holes just 200-billionths of a meter wide and not cause any side effects. The holes will not allow permeation of larger immunocytes, such as leukocytes and antibodies, and the recipient would not need immunosuppressants.
The research group has applied to Kyoto University's bioethics committee to start clinical trials by the end of this year.
Categories: Blood Sugar, Diabetes, Insulin, Islet & Pancreas Transplant
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Apr 1, 1999
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Diabetes Health
Diabetes Health is the essential resource for people living with diabetes- both newly diagnosed and experienced as well as the professionals who care for them. We provide balanced expert news and information on living healthfully with diabetes. Each issue includes cutting-edge editorial coverage of new products, research, treatment options, and meaningful lifestyle issues.
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Topics
- Diabetic / Diabetes Health
- Type 1 / 1.5 Diabetes
- Type 2 Diabetes
- Blood Glucose / Sugar
- High/Low Blood Sugar / Fast Acting Glucose
- Insulin- Pumps, Pens & Syringes
- Continuous Glucose Monitors, CGM, Infusion Sets
- Type 2 Medications
- Hyperglycemia
- Hypoglycemia
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