Lipoatrophy Associated with Humalog Use in Insulin-Pump Therapy

Apr 1, 2001

If you use lispro (Humalog) insulin in your pump and are seeing dents in your skin at your infusion sites, a switch in insulin can stop the problem.

The situation, called lipoatrophy, happens when the fatty tissue under the skin disappears. Lipoatrophy, more common in the past, was believed to have been caused by reactions to insulins that are not as pure as today's human-origin compounds. However, at least three recent cases of lipoatrophy involving the use of Humalog in a pump has led doctors from the Yale University and West Virginia University schools of medicine to caution others to be on the lookout for the problem.

The doctors, writing in the "Letters" section of the January 2001 issue of Diabetes Care, observed two incidents of lipoatrophy and received correspondence from a colleague who observed one case.

Switching to human-based buffered Regular insulin in the form of Velosulin alleviated the problems with lipoatrophy.

Doctors say evidence points to Humalog—not the delivery system—as being the primary factor in causing lipoatrophy.

Click Here To View Or Post Comments

Categories: Complications & Care, Diabetes, Diabetes, Insulin, Insulin Pumps, Type 1 Issues

Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • 12th Annual Product Reference Guide
  • Insulin Syringe Chart
  • Insulin Pen Needles Chart
  • Fast-Acting Glucose
  • Sharps Disposal
  • Blood Glucose Meters Chart
  • Insulin Pumps Chart
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter

Top Rated
Print | Email | Share | Comments (5)

You May Also Be Interested In...

Click Here To View Or Post Comments

Comments 5 comments - Apr 1, 2001

©1991-2015 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.