Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • 12 Tips for Traveling With Diabetes
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter
Latest
Popular
Top Rated
Diabetes Archives
Print | Email | Share | Comments (1)

Vaccine May Prevent Type 1-Shown to Work Successfully in Mice


Jun 1, 2001
Researchers at the University of North Carolina at Chapel-Hill may have just proven that certain types of vaccines can help prevent and treat type 1 diabetes.

Roland Tisch, PhD, and colleagues experimented with vaccines using plasmid DNA, genetic material that is taken from bacteria. According to research published in the February 1 issue of the Journal of Immunology, the vaccines successfully prevented and mitigated the progression of diabetes in mice.

The researchers injected mice with the vaccines three times in three weeks. The majority of them remained diabetes-free for over a year.

The vaccines were engineered to re-establish the balance between two immune cells-Th1 and Th2. With type 1, Th1 cells malfunction by attacking insulin-producing beta cells. The cells in the vaccines were designed to act like two different proteins, one that activates islet beta cell-detecting T cells, and the other that stops the Th1 cells from attacking when they shouldn't.

"Our approach was relatively simple," said Dr. Tisch in an interview with News Rx. "The vaccines allowed us to selectively suppress the body's auto-immune response while leaving the remainder of the immune response intact."

Tisch also indicated how researchers anticipate that the vaccines will be used: "One of the appealing features of plasmid DNA vaccinesÉis that the DNA persists for long periodsÉ Ideally, human patients might require injection of plasmid DNA vaccines only every year or two."

-R. McLean


Categories: Diabetes, Diabetes, General, Insulin, Type 1 Issues



You May Also Be Interested In...


Click Here To View Or Post Comments

Jun 1, 2001

©1991-2014 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.