Niacin Shown to Control Cholesterol in the Body

Niaspan from Kos Pharmaceuticals, Inc.

| Jul 1, 2001

A recent study shows that taking extended-release niacin, a vitamin known to lower cholesterol, helps reduce risk of cardiovascular disease without affecting sugar levels in the body.

Research conducted by Kos Pharmaceuticals Inc., the maker of Niaspan—a once-daily niacin formulation—was presented on March 19 at the 50th Annual Scientific Session of the American College of Cardiology. According to Kos Pharmaceuticals, results of the randomized, double-blind, placebo-controlled, multi-center study showed that taking the supplement helped control several types of cholesterol in the body.

One hundred and forty eight patients with dyslipidemia (disease in the lipids) or abnormal lipid levels were chosen for the trial. In a double-blinded study at 20 different locations, they received either 1,000 or 1,500 milligrams of either Niaspan or a placebo.

After six weeks of treatment, high-density lipoprotein (HDL), or good cholesterol, increased by 24 percent for patients taking 1,500 milli-grams of Niaspan. HDL levels rose 20 percent for those taking 1,000 milligrams and four percent for those taking a placebo. Triglyceride went down 29 percent for those on the 1,500-milligram dose of the drug and 15 percent for those on the 1,000-milligram dose.

Researchers also note the important fact that the patients' HbA1c levels were not significantly affected by the treatment.

Scott M. Grundy, MD, PhD, professor of Internal Medicine and Biochemistry and director for University of Texas Southwestern's Center of Human Nutrition, states, "Use of extended-release niacin in the proper doses can provide a great deal of benefit in safely altering the lipid profile of those with diabetes."

Due to the fact that approximately half of the patients studied were already taking an anti-cholesterol drug, investigators also conclude that people with higher-than-normal lipid levels may want to take extended-release niacin in combination with an anti-cholesterol drug to treat the problem.

In an interview with Diabetes Health, Keith Campbell, RpH, CDE, professor of pharmacology at Washington State University, stated that patients should use niacin under the direction of a physician.

Click Here To View Or Post Comments

Categories: A1c Test, Diabetes, Diabetes, Heart Care & Heart Disease, Vitamins

Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • 12th Annual Product Reference Guide
  • Insulin Syringe Chart
  • Insulin Pen Needles Chart
  • Fast-Acting Glucose
  • Sharps Disposal
  • Blood Glucose Meters Chart
  • Insulin Pumps Chart
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter

Top Rated
Print | Email | Share | Comments (0)

You May Also Be Interested In...


Add your comments about this article below. You can add comments as a registered user or anonymously. If you choose to post anonymously your comments will be sent to our moderator for approval before they appear on this page. If you choose to post as a registered user your comments will appear instantly.

When voicing your views via the comment feature, please respect the Diabetes Health community by refraining from comments that could be considered offensive to other people. Diabetes Health reserves the right to remove comments when necessary to maintain the cordial voice of the diabetes community.

For your privacy and protection, we ask that you do not include personal details such as address or telephone number in any comments posted.

Don't have your Diabetes Health Username? Register now and add your comments to all our content.

Have Your Say...

Username: Password:
©1991-2015 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.