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Type 2s Say They Like The Pump Better/Researchers Say Novolog Safe for Pump Use
Type 2s Say They Like the Pump Better
There has not been a wealth of research into whether insulin-dependent type 2s would prefer insulin-pump therapy to injection therapy. This led four researchers from Boston to conduct a study of 126 insulin-treated type 2s, which was presented at this year's ADA scientific sessions.
The researchers report, "Type 2 patients requiring intensive-insulin therapy demonstrated greater satisfaction with the pump compared to multiple daily injections using a pen."
For the study, 60 people were randomized to multiple subcutaneous pen injection, while 66 people were put on the pump. Patient-satisfaction questionnaires were passed out at 16 and 24 weeks into the study.
The researchers discovered that:
Researchers Say Novolog Safe for Pump Use
The soon-to-be-released fast-acting insulin aspart (Novolog), according to Bruce Bode, MD, of Atlanta Diabetes Association, is "safe and effective in continuous subcutaneous insulin infusion and is suitable for use in external insulin pumps."
Bode and researchers from around the country presented results of their study at the recent ADA scientific sessions. For their study, they randomized 146 adults with type 1 diabetes to receive either Novolog buffered regular insulin (Velosulin) or lispro (Humalog) in an external pump for 16 weeks. Before the study, all subjects had four weeks of treatment with Velosulin.
At the beginning of the study, HbA1c was similar between the treatment groups—Novolog 7.34%; Velosulin 7.47% and Humalog 7.29%. By the end of the study, the Novolog group's A1c control remained the same, while the Velosulin and Humalog group's A1c's got slightly worse (7.63% and 7.47%, respectively).
The researchers note that after-meal BG values were lower in the Novolog compared to Velosulin group but similar to the Humalog group. However, they were "significantly lower 90 minutes after dinner in the [Novolog] group (136 mg/dl) when compared to the Velosulin (171 mg/dl) and Humalog (164 mg/dl) groups.
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