Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • 12 Tips for Traveling With Diabetes
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter
Latest
Popular
Top Rated
Diabetes Health Reference Charts
Insulin Archives
Print | Email | Share | Comments (0)

Concerns About Humulin

Mar 1, 2002

Q: All insulin vials are packaged with an insert that tells you not to use the insulin if the solids stay caked when you roll or shake the vial. For around 23 years, I used Iletin I and never encountered that problem. The solids always distributed themselves through the liquid the way they were supposed to. In two or three years of using Humulin, however, I've had to throw away at least four vials because the insulin cakes up and will not uncake itself no matter how much rolling, tipping or shaking I do. I can't imagine why the old "standard" insulin, which worked better in general, cost less than what we're using now, and tended to survive better on the shelf, is no longer produced in this country but is apparently still made in eastern Europe, where medicine is supposedly less advanced!

Wade Dowdell
Clements, California

A: As you point out, it is important to resuspend all insulins that come in the form of a suspension, such as Humulin 70/30, NPH, Lente, Ultralente and Humalog Mix 75/25. As the product information indicates, Humulin NPH should look uniformly cloudy or milky after mixing. Do not use it if the insulin substance (the white material) remains visibly separated from the liquid after mixing. Do not use the vial or pen if there are clumps in the insulin after mixing or if solid white particles stick to the walls of the vial or cartridge, giving it a frosted appearance. If you note anything unusual in the appearance of an insulin suspension, or if you notice your insulin requirements changing markedly, you should consult your doctor.

John H. Holcombe, MD
Medical Adviser
Eli Lilly and Company
Indianapolis, Indiana

 


Categories: Insulin, Pens



You May Also Be Interested In...


Click Here To View Or Post Comments

Comments 0 comments - Mar 1, 2002

©1991-2014 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.