Pravachol: How Cholesterol-Lowering May Help You

| Feb 1, 2004

The cholesterol-lowering drug Pravachol (pravastatin), when administered at 40 milligrams per day over six years, helps prevent cardiovascular events including stroke in people with diabetes or with impaired fasting glucose (IFG) and established coronary disease.

The LIPID trial (long-term intervention with pravastatin in ischemic disease) conducted in Australia studied 9,014 patients including 1,077 with diabetes and 940 with IFG.

Use of Pravachol reduced the risk of any cardiovascular event from 52.7 to 45.2 percent in subjects with diabetes and reduced the risk of stroke from 9.9 to 6.3 percent. However, it did not reduce the incidence of diabetes in those not previously diagnosed.

Treatment with “statin” drugs to lower cholesterol does pay off, however.

Use of pravastatin prevented one major coronary event (death or nonfatal myocardial infarction) over a six-year period in 23 patients with IFG and 18 patients with diabetes.

In the placebo-treated group the risk of a major coronary disease event was 61 percent higher in subjects with diabetes and 23 percent higher in those with IFG than in subjects with normal fasting glucose.

Diabetes Care, October 2003

Click Here To View Or Post Comments

Categories: Diabetes, Diabetes, Heart Care & Heart Disease, Medications, Medications Research, Other Lab Tests, Type 2 Medications

Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • 12th Annual Product Reference Guide
  • Insulin Syringe Chart
  • Insulin Pen Needles Chart
  • Fast-Acting Glucose
  • Sharps Disposal
  • Blood Glucose Meters Chart
  • Insulin Pumps Chart
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter

Top Rated
Print | Email | Share | Comments (0)

You May Also Be Interested In...


Add your comments about this article below. You can add comments as a registered user or anonymously. If you choose to post anonymously your comments will be sent to our moderator for approval before they appear on this page. If you choose to post as a registered user your comments will appear instantly.

When voicing your views via the comment feature, please respect the Diabetes Health community by refraining from comments that could be considered offensive to other people. Diabetes Health reserves the right to remove comments when necessary to maintain the cordial voice of the diabetes community.

For your privacy and protection, we ask that you do not include personal details such as address or telephone number in any comments posted.

Don't have your Diabetes Health Username? Register now and add your comments to all our content.

Have Your Say...

Username: Password:
©1991-2015 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.