Cut Through the Fat

TZD Works or Without Reductions in Fat Distribution

| Mar 1, 2004

Researchers have long understood that thiazolidinediones (TZDs) improve the action of insulin while increasing total fat mass as well. After studying 39 upper-body obese, insulin-resistant, but non-diabetic men and postmenopausal women, researchers concluded that patients on pioglitazone (Actos) improved their insulin resistance level regardless of the rise in intra-abdominal fat that accompanied the therapy.

Half the patients in the study were randomly assigned to receive 30 mg daily of Actos, while the other half participated in a diet and exercise program that yielded an approximate 12-kg weight loss over 20 weeks.

In spite of the increase in total body fat, particularly in the lower body, the patients on Actos experienced an improvement in insulin sensitivity.

Diabetes Care, November 2003

Click Here To View Or Post Comments

Categories: Diabetes, Diabetes, Insulin, Medications Research, Type 2 Medications


Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • What's on the Horizon with Diabetes Research and Therapy
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter

Latest
Popular
Top Rated
Print | Email | Share | Comments (0)

You May Also Be Interested In...


Click Here To View Or Post Comments

Comments 0 comments - Mar 1, 2004

©1991-2014 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.