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New Therapy Helps Freshly Isolated Islets Survive
Researchers in Italy and the United States collaborated to determine whether the peptide hormone glucagon-like peptide 1 (GLP-1) could improve function and inhibit programmed cell death or suicide.
Human islets were cultured for five days either with or without GLP-1. They were studied for viability, the absence or presence of cell suicide and glucose-dependent insulin production.
Results showed better-preserved three-dimensional islet morphology in the GLP-1 group than the controls. Reduction of suicide cells was particularly evident at day three.
Researchers concluded that GLP-1 preserves morphology, improves functions and inhibits cell suicide.
-Endocrinology, December 2003
Categories: Insulin, Islet & Pancreas Transplant, Research
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Apr 1, 2004
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Diabetes Health
Diabetes Health is the essential resource for people living with diabetes- both newly diagnosed and experienced as well as the professionals who care for them. We provide balanced expert news and information on living healthfully with diabetes. Each issue includes cutting-edge editorial coverage of new products, research, treatment options, and meaningful lifestyle issues.
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