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Stiffness and impaired blood flow in the arteries of the lower legs may help identify diabetic patients with possible coronary artery disease.
Japanese researchers observed 102 asymptomatic type 2 diabetic patients with no history of cardiovascular complications. Coronary artery calcium (CAC) score was used as a marker.
Patients with the highest CAC scores, which indicate possible coronary artery disease, showed the highest brachial-ankle PWV and resistive index and the lowest total flow volume. Both brachial-ankle PWV and resistive index were positively correlated and total flow was negatively correlated with the CAC score.
—Diabetes Care, October 2004
Dec 1, 2004