Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • 12 Tips for Traveling With Diabetes
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter
Latest
Popular
Top Rated
Type 2 Issues Archives
Print | Email | Share | Comments (0)

Islet Cell Regeneration

Jan 1, 2005

The content for this column is provided by the Iacocca Foundation

A New Therapy for Diabetes

A new generation of therapies for type 1 diabetes is likely to come from within our own bodies. The idea of pancreatic islet regeneration as a therapy for diabetes first came to light back in 2001, and it is now a hot topic among researchers in the field.

What do we mean by regeneration?

Regeneration takes advantage of the body’s capacity for healing and renewal, assuming that the underlying problem of type 1 diabetes—the immune-cell attack on the islets in the pancreas—can be overcome. The work done at the Faustman laboratory over the past five years suggests that the diabetic pancreas has immense regenerative potential once the immune cells are stopped from attacking and destroying the islet cells. This approach is now coming to the forefront in diabetes research.

Over the past two years, a multitude of scientific papers have suggested that there are most likely many ways to regenerate these islet cells. A wide range of cell types and existing precursor cells exist, some in the pancreas and some in the spleen, in both normal mice and humans. If the capacity to regenerate can be harnessed to replenish insulin-producing islet cells that are destroyed by disease, then perhaps a “transplant” of stem cells or islets may not be needed.

Eliminating disease

As the Faustman laboratory moves forward, the goal will be to eliminate disease in humans with type 1 diabetes and to stop the immune-cell attack on the islets. Faustman’s research suggests that if the underlying disease is eliminated, regeneration can occur. If this is true in humans, successes with this approach could apply both to type 1 and type 2 diabetes. Disease elimination could uncover the remarkable process of self-healing, a process not previously considered as a potential avenue in the search for a cure for diabetes.


How Can I Help?

The cost of the first three years of clinical trials at Massachusetts General Hospital is estimated at $11 million. Contribute to the JoinLeeNow campaign and support these efforts to cure type 1 diabetes in humans. Donations may be made over the Internet or by mail.

Internet: To make a donation over the Internet, please visit www.JoinLeeNow.org and click on “Donate Now.”

U.S. Mail: To mail your donation, please make checks payable to “Iacocca Foundation.” Send donations to the following address:

The Iacocca Foundation
17 Arlington Street
Boston, MA 02116

Gifts: Give the gift of a donation to support important diabetes research. Donations can be made in a loved one’s name. For more information about gift-giving, go to www.JoinLeeNow.org or call Danielle Briscoe at (212) 255-5340.

Volunteer: For information on becoming a city captain and helping with local efforts to raise money for these research trials, or if you have other inquiries, please call Danielle Briscoe at (212) 255-5340 or send e-mail to danielle@corinthgroup.com.


Categories: Celebrities, Diabetes, Diabetes, Insulin, Type 1 Issues, Type 2 Issues



You May Also Be Interested In...


Click Here To View Or Post Comments

Jan 1, 2005

©1991-2014 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.