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Diabetics have an increased mortality associated with peripheral arterial disease (PAD) progression.
Minnesota residents aged 50 to 70 years with PAD and/or diabetes were identified from the Mayo Clinic diagnostic registry and monitored from 1977 through 1999. At baseline, 149 had PAD alone, 238 had diabetes alone and 186 had both conditions. Within each group the survival rate was lower than expected.
Among the 449 who returned at four years, the risk of death was greater for those whose PAD had progressed. The adjusted risk of death for both conditions was 2.2 times that for PAD alone.
For those who had only diabetes at baseline, 100 percent who had PAD progression died by the end of 1999. The increased mortality associated with PAD progression was significant only for individuals with diabetes, alone or with PAD at baseline.
The researchers say detecting and monitoring PAD in diabetic patients is of the utmost importance.
—Diabetes Care, December 2004
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