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Italian researchers say that kidney disease is a “significant predictor” of death, and that people who have kidney problems at the time of their diabetes diagnosis should be treated aggressively from the onset.
In a study aimed at evaluating the pattern and predictors of death after a 4½-year follow-up in type 2s, 1,200 patients with a diabetes duration of less than five years and 2,692 patients with a diabetes duration of more than five years were evaluated.
Survival after four years was 92 and 83.7 percent, respectively. Most deaths, the researchers say, are due to cardiovascular diseases (36 and 41 percent, respectively).
“The duration of diabetes is no longer a significant predictor of death after adjustments for age, HbA1c and chronic complications (which are all significantly higher in patients who have had diabetes for longer time),” write the researchers.
Kidney disease, they add, is “significantly associated with cardiovascular deaths in the younger cohort.”
—Nutrition, Metabolism and Cardiovascular Diseases, January 2006
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