Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • 12 Tips for Traveling With Diabetes
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter
Latest
Popular
Top Rated
Diabetes Health Reference Charts
Type 1 Issues Archives
Print | Email | Share | Comments (0)

Majority of Edmonton Protocol Participants Don’t Stay Off Insulin After One Year


Feb 1, 2007

An islet.

Despite successfully restoring insulin production and blood-glucose stability after transplantation, insulin independence is usually not sustainable after the Edmonton Protocol.

The Edmonton Protocol team, lead by James Shapiro, MD, PhD, FRCS, conducted an international, multi-center trial to “explore the feasibility and reproducibility of islet transplantation with the use of a single common protocol.” Thirty-six type 1s were enrolled and underwent islet transplantation at nine international sites.

“Of the 36 subjects, 16 met the primary end point, 10 had partial function, and 10 had complete graft loss one year after the final transplantation,” write the researchers. “A total of 21 subjects attained insulin independence with good glycemic control at any point throughout the trial. Of these subjects, 16 required insulin again at two years; five of the 16 subjects who reached the primary end point remained insulin-independent at two years.”

New England Journal of Medicine, September 28, 2006


Categories: Bariatric Surgery, Insulin, Research, Type 1 Issues



You May Also Be Interested In...


Comments


Add your comments about this article below. You can add comments as a registered user or anonymously. If you choose to post anonymously your comments will be sent to our moderator for approval before they appear on this page. If you choose to post as a registered user your comments will appear instantly.

When voicing your views via the comment feature, please respect the Diabetes Health community by refraining from comments that could be considered offensive to other people. Diabetes Health reserves the right to remove comments when necessary to maintain the cordial voice of the diabetes community.

For your privacy and protection, we ask that you do not include personal details such as address or telephone number in any comments posted.

Don't have your Diabetes Health Username? Register now and add your comments to all our content.

Have Your Say...


Username: Password:
Comment:
©1991-2014 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.