Visceral Fat, Guilty of Systemic Inflammation

| Apr 14, 2007

If you have to be fat, it’s a far, far better thing to be fat in places other than your belly. Visceral fat, the kind deep inside the abdomen that inextricably surrounds internal organs, is an organ in itself, secreting hormones and active molecules, called cytokines, which are bad for your health.

Now a study from the Washington University School of medicine in St. Louis, published in February 2007 Diabetes, has shown that visceral fat secretes molecules that increase system-wide inflammation.

The study involved 25 obese patients who were undergoing gastric bypass surgery. Since the researchers couldn’t remove their visceral fat, which was entangled in intestines and other organs, they sampled blood from the portal vein, which drains the visceral fat.  They found that portal vein blood had levels of interleukin-6 (IL-6), an inflammatory molecule, 50 times higher than blood from the radial artery of the arm.  Clearly, the visceral fat was secreting high levels of IL-6 into the portal vein blood.

Increased levels of IL-6 in the portal vein are associated with high concentrations of C-reactive protein (CRP) in the body. High CRP levels are related to inflammation.  Chronic inflammation is associated with insulin resistance, type 2 diabetes, hypertension, and atherosclerosis, and may also be implicated in cancer and aging. 

The lesson here? Ban the belly fat! Walk a little more, eat a little less, and eradicate that visceral fat.

Click Here To View Or Post Comments

Categories: Diabetes, Diabetes, Insulin, Nutrition Advice, Type 2 Issues


Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter

Latest
Popular
Top Rated
Print | Email | Share | Comments (1)

You May Also Be Interested In...


Comments

Posted by Anonymous on 7 November 2007

My son ( and late husband ) bothgot a large deposit of 'fat' around the middle just where they put in the insulin needles It is worrying because neither is or was overweight. Does anyone else have this problem ? anonymous.


Add your comments about this article below. You can add comments as a registered user or anonymously. If you choose to post anonymously your comments will be sent to our moderator for approval before they appear on this page. If you choose to post as a registered user your comments will appear instantly.

When voicing your views via the comment feature, please respect the Diabetes Health community by refraining from comments that could be considered offensive to other people. Diabetes Health reserves the right to remove comments when necessary to maintain the cordial voice of the diabetes community.

For your privacy and protection, we ask that you do not include personal details such as address or telephone number in any comments posted.

Don't have your Diabetes Health Username? Register now and add your comments to all our content.

Have Your Say...


Username: Password:
Comment:
©1991-2014 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.