Liquid Fructose Gives Ratty A Fatty Liver

| May 18, 2007

Here's yet another bit of research connecting fat to fructose-laden beverages A study recently published in Hepatology shows that fructose-laden water (10% wt/vol) decreases liver fat breakdown and causes lipid accumulation in rats.

This change wasnt observed in glucose-fed rats. The rats that drank liquid fructose, unlike those getting glucose, had extra leptin in their blood. However, their livers did not behave as expected given the high levels of leptin, a hormone that generally accelerates fat oxidation in the liver and reduces its synthesis.

The researchers concluded that the fructose-caused lipid accumulation and fatty liver was caused by resistance to the extra leptin. The resistance to leptin decreased the action of a specific receptor (PPAR-alpha), which controls fatty acid oxidation. The researchers noted that because PPAR-alpha activity is lower in humans than in rats, liquid fructose ingestion could cause even worse effects in humans.

Click Here To View Or Post Comments

Categories: Nutrition Research


Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter

Latest
Popular
Top Rated
Print | Email | Share | Comments (0)

You May Also Be Interested In...


Comments


Add your comments about this article below. You can add comments as a registered user or anonymously. If you choose to post anonymously your comments will be sent to our moderator for approval before they appear on this page. If you choose to post as a registered user your comments will appear instantly.

When voicing your views via the comment feature, please respect the Diabetes Health community by refraining from comments that could be considered offensive to other people. Diabetes Health reserves the right to remove comments when necessary to maintain the cordial voice of the diabetes community.

For your privacy and protection, we ask that you do not include personal details such as address or telephone number in any comments posted.

Don't have your Diabetes Health Username? Register now and add your comments to all our content.

Have Your Say...


Username: Password:
Comment:
©1991-2014 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.