Gastric Bypass Surgery Being Considered as Treatment for Type 2

| May 20, 2007

Bariatric surgery, formerly used only for treating obesity, is being explored as a cure for type 2 diabetes in normal weight or moderately overweight people.

A recent analysis of 22,094 patients showed that 84 percent who underwent Roux-en-Y gastric bypass (RYGB) experienced complete reversal of their type 2 diabetes. Most of them stopped their oral meds or insulin before they even left the hospital. 

Researchers initially thought that weight loss caused the remission of type 2, but new findings are pointing to hormonal and metabolic changes caused by the surgery.  Ghrelin, a peptide that stimulates appetite, is decreased after bypass surgery.  Other peptides secreted by intestinal cells, including glucagon-like peptide 1 (GLP-1), increase after the operation. (GLP-1 is the protein that Byetta mimics.)

Recently, the RYGB procedure was used on two mildly overweight patients.  Within a month post-surgery, these patients had dramatically lower fasting glucose, fasting insulin, and A1c’s.

Specific recommendations regarding the audience for this surgery are due out this summer.  The researchers believe that a bit of a turf war may consequently develop between endocrinologists and bariatric surgeons, who have their eye on type 2s as a potential market for surgical procedures.

Source: Medscape Medical News
Amercian Association of Clinical Endocrinologists

Click Here To View Or Post Comments

Related Article

Bariatric Surgery: The Operation Diet

Jun 28, 2007

Categories: A1c Test, Diabetes, Diabetes, Hospital Care, Insulin, Type 2 Issues, Weight Loss

Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • 12th Annual Product Reference Guide
  • Insulin Syringe Chart
  • Insulin Pen Needles Chart
  • Fast-Acting Glucose
  • Sharps Disposal
  • Blood Glucose Meters Chart
  • Insulin Pumps Chart
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter

Top Rated
Print | Email | Share | Comments (1)

You May Also Be Interested In...


Posted by Anonymous on 12 September 2008

there appears to be not much info as to exactly why the surgery works. Is it the absence of food contact with the duodenum?

Add your comments about this article below. You can add comments as a registered user or anonymously. If you choose to post anonymously your comments will be sent to our moderator for approval before they appear on this page. If you choose to post as a registered user your comments will appear instantly.

When voicing your views via the comment feature, please respect the Diabetes Health community by refraining from comments that could be considered offensive to other people. Diabetes Health reserves the right to remove comments when necessary to maintain the cordial voice of the diabetes community.

For your privacy and protection, we ask that you do not include personal details such as address or telephone number in any comments posted.

Don't have your Diabetes Health Username? Register now and add your comments to all our content.

Have Your Say...

Username: Password:
©1991-2015 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.