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New Insulin-Secreting Beta Cells Come From Beta Cell Division, Not From Adult Stem Cells
Researchers from Philadelphia have just discovered that beta cells, the insulin-producing cells of the pancreas, divide, albeit slowly, to make new beta cells. Adult stem cells, which are precursors of new skin, intestines, and other tissues, apparently do not differentiate into beta cells or other pancreatic tissue.
Instead, beta cells replicate themselves, basically functioning as their own stem cells.
Dr. Jake A. Kushner and his team were able to see the process occur by giving rats a sequence of colored dyes in their drinking water. The idea was that dividing cells would be all the same color; that is, the color of the single cell from which they came. The researchers were able to see clusters of beta cells in the pancreas that were all the same color, indicating that one cell had divided into many cells.
In contrast, the colors of cells in the rats' intestine were blended, indicating that they had divided multiple times from specialized cells - possibly from adult stem cells.
The researchers hope that this finding will eventually lead to an understanding of how to induce beta cells to divide and replenish their numbers in people who have type 1 diabetes.
Source: PharmaLive.com
Categories: Diabetes, Diabetes, Insulin, Islet & Pancreas Transplant, Type 1 Issues
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Jun 2, 2007
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Diabetes Health
Diabetes Health is the essential resource for people living with diabetes- both newly diagnosed and experienced as well as the professionals who care for them. We provide balanced expert news and information on living healthfully with diabetes. Each issue includes cutting-edge editorial coverage of new products, research, treatment options, and meaningful lifestyle issues.
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Topics
- Diabetic / Diabetes Health
- Type 1 / 1.5 Diabetes
- Type 2 Diabetes
- Blood Glucose / Sugar
- High/Low Blood Sugar / Fast Acting Glucose
- Insulin- Pumps, Pens & Syringes
- Continuous Glucose Monitors, CGM, Infusion Sets
- Type 2 Medications
- Hyperglycemia
- Hypoglycemia
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