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Thinner artery walls are a good thing, because thicker ones indicate atherosclerosis and an increased risk of heart attack. In a study published in the December 2006 Journal of the American Medical Association, pioglitazone (Actos, a thiazolidinedione) was compared to glimepiride (a sulfonylurea) with regard to carotid artery thickness.
For a period of 18 months, 462 patients with type 2 diabetes were given one or the other. In the end, the thickness of the artery in the glimepiride group increased by a tiny amount, 0.012 millimeters. In the pioglitazone group, average thickness fell by an even tinier amount, 0.001 millimeters.
Jun 9, 2007
Diabetes Health is the essential resource for people living with diabetes- both newly diagnosed and experienced as well as the professionals who care for them. We provide balanced expert news and information on living healthfully with diabetes. Each issue includes cutting-edge editorial coverage of new products, research, treatment options, and meaningful lifestyle issues.