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Cord Blood Stem Cells Engineered to Produce Insulin
Given that babies are born by the cartloads every day, cord blood is an easy source of fetal stem cells, especially because it’s free of the controversy surrounding embryonic stem cells.
Now U.S. and British researchers have reportedly harvested a batch of stem cells from cord blood and then engineered the cells to resemble beta cells, the insulin-producing pancreatic cells that are destroyed in type 1 diabetes. The stem cells apparently did produce insulin, and a little C-peptide also was found in the test tube, confirming that the insulin had been generated by the stem cells.
On the other hand, recent research concluded that beta cells reproduce themselves and do not come from adult stem cells. That research found that adult stem cells, although they are precursors of new skin, intestines, and other tissues, apparently do not differentiate into beta cells or other pancreatic tissue.
For these reasons, states our board member Dr. Nancy Bohannon, she has been advising her type 1 patients to bank the cord blood of their children for the past decade, in the hope that eventually scientists will be able to use it to develop functional, glucose-responsive beta cells.
Categories: Diabetes, Diabetes, Insulin, Islet & Pancreas Transplant, Type 1 Issues
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Diabetes Health
Diabetes Health is the essential resource for people living with diabetes- both newly diagnosed and experienced as well as the professionals who care for them. We provide balanced expert news and information on living healthfully with diabetes. Each issue includes cutting-edge editorial coverage of new products, research, treatment options, and meaningful lifestyle issues.
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