Incretin Therapy Is Rather Good At Lowering Blood Sugar, Says Study Review

| Aug 16, 2007

A meta-analysis of 29 studies, none longer than six months, has shown that incretin therapies (like Byetta and Januvia) are moderately effective in lowering blood glucose in people with type 2 diabetes, especially after meals.

Better yet, they do so without the weight gain associated with many type 2 medications.

Incretin therapy uses drugs that increase the action of GLP-1, a hormone secreted by the intestine that lowers blood glucose. Studies of two types of incretin therapy were assessed: A GLP-1 analogue, exenatide (Byetta), which is an injectable synthetic copy of GLP-1 that lasts much longer in the body than natural GLP-1; and DPP-4 inhibitors, like sitagliptin (Januvia), which are pills that block the breakdown of natural GLP-1, again making it last longer in the body.

The results of the meta-analysis indicate that incretin therapy appears to be safe, at least over the short run, with minimal negative side effects. For people who still have adequate beta cells, are at risk for hypoglycemia, and need to lose weight, it appears to be a good alternative. However, it needs lengthier evaluation to assess its long-term safety and effectiveness.

Journal of the American Medical Association, July 2007

Click Here To View Or Post Comments

Categories: Blood Glucose, Blood Sugar, Diabetes, Diabetes, Losing weight, Low Blood Sugar, Type 2 Issues, Type 2 Medications

Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • 12th Annual Product Reference Guide
  • Insulin Syringe Chart
  • Insulin Pen Needles Chart
  • Fast-Acting Glucose
  • Sharps Disposal
  • Blood Glucose Meters Chart
  • Insulin Pumps Chart
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter

Top Rated
Print | Email | Share | Comments (0)

You May Also Be Interested In...

Click Here To View Or Post Comments

Aug 16, 2007

©1991-2015 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.