Symlin Promising as Weight Loss Drug

| Oct 12, 2007

Symlin, or pramlintide, is synthetic amylin, a natural hormone that slows stomach emptying and leads to a feeling of fullness. Currently Symlin is used to dampen blood sugar rises in people with diabetes, but it's showing potential as a weight loss drug as well, according to a recent study.

The researchers examined 204 obese subjects for sixteen weeks, half of whom received Symlin injections thrice daily before meals and half of whom were given a placebo on the same schedule.

About 31 percent of the Symlin group lost five percent or more of their weight, compared to only two percent of the placebo group. On average, they lost about eight pounds. Furthermore, 72 percent of them said that their appetite control had improved, versus 31 percent of the placebo group, and 52 percent said their wellbeing had improved, versus only 17 percent of the placebo patients.

Symlin has not yet been approved as a weight loss drug. It is approved as an add-on treatment for people with type 1 who fail to reach glucose control on optimal insulin therapy, or for type 2s who fail to reach glucose control on optimal insulin therapy, with or without concurrent use of metformin or a sulfonylurea. It requires a prescription from your doctor, and insurance often doesn't pay for it. The average wholesale price is about $99 to $179 per month.

Sources: Medline Plus; Journal of Clinical Endocrinology and Metabolism, August 2007

Click Here To View Or Post Comments

Categories: Blood Sugar, Diabetes, Diabetes, Insulin, Professional Issues, Symlin, Type 1 Issues, Type 2 Issues, Weight Loss


Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • What's on the Horizon with Diabetes Research and Therapy
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter

Latest
Popular
Top Rated
Print | Email | Share | Comments (1)

You May Also Be Interested In...


Click Here To View Or Post Comments

Oct 12, 2007

©1991-2014 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.