High Levels of "Good" Cholesterol May Be a Bad Thing

| Feb 16, 2008

That ancient Greek advice, "moderation in all things," may apply not only to human conduct, but also to the natural world.

A Dutch research study suggests that high levels of "good" HDL cholesterol are not so good - in fact, they may actually increase the risk of a cardiovascular event.

That conclusion comes from the Academic Medical Center in the Netherlands. Scientists there analyzed data from a study involving almost 8,900 patients to assess the benefits of high-dose statin therapy for preventing the recurrence of coronary events.

What the researchers found was that very high levels of HDL cholesterol were tied to increased risk of a major cardiovascular event. After adjusting for other factors, they found each 12-point increase in HDL cholesterol raised that risk by 21 percent.

On the other hand, the study found that apolipoprotein A-I, the major protein component of HDL, continues to be linked to a reduced risk of coronary disease, even at high levels.

In an editorial commenting on the findings, Dr. Jacques Genest of McGill University in Montreal writes, "First, naturally occurring high levels of HDL cholesterol may not protect against heart disease, and second, and herein lies the most important and provocative finding, HDL cholesterol as a therapeutic goal may be fraught with potential dangers."

Source: Journal of the American College of Cardiology, February, 2008

Click Here To View Or Post Comments

Categories: Heart Care & Heart Disease, Professional Issues

Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • 12th Annual Product Reference Guide
  • Insulin Syringe Chart
  • Insulin Pen Needles Chart
  • Fast-Acting Glucose
  • Sharps Disposal
  • Blood Glucose Meters Chart
  • Insulin Pumps Chart
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter

Top Rated
Print | Email | Share | Comments (12)

You May Also Be Interested In...

Click Here To View Or Post Comments

Comments 12 comments - Feb 16, 2008

©1991-2015 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.