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Glucose-controlling metformin, the generic drug that is the first medication that many newly diagnosed type 2s take, could soon be available in a chewing gum.
Glucose-controlling metformin, the generic drug that is the first medication for many newly diagnosed type 2s, could soon be available in a chewing gum.
That’s the hope held by Massachusetts-based Generex Biotechnology Corporation, which has announced that it is ready to test its proprietary metformin chewing gum product, MetControl™, on 36 volunteer patients. In the study, Generex will compare the speed and efficacy of MetControl to that of immediate-release metformin tablets.
Metformin is the most prescribed drug for type 2 patients. Nevertheless, many people with diabetes avoid using it because of its gastrointestinal side effects, large pill size and bitter taste. These factors are especially off-putting to the increasing number of children being diagnosed with type 2.
Generex believes that the delivery of metformin in a good-tasting chewing gum will make the drug more acceptable to these patients and thereby increase adherence with diabetes therapy.
Because metformin is safe, well known and well established, the company does not anticipate taking as long to come to market with MetControl as it would with a product containing a new active compound. Such products typically must undergo stringent testing that can last years.
Categories: Diabetes, Diabetes, Type 2 Issues, Type 2 Medications
May 15, 2008
Diabetes Health is the essential resource for people living with diabetes- both newly diagnosed and experienced as well as the professionals who care for them. We provide balanced expert news and information on living healthfully with diabetes. Each issue includes cutting-edge editorial coverage of new products, research, treatment options, and meaningful lifestyle issues.


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