Metformin May Aid in Weight Loss for Obese Pre-Diabetic Teen Girls

By itself, the goal-setting helped neither group achieve significant weight loss. However, 60 percent of the metformin group’s members who also cut back on their food portions experienced a decrease in their body mass index of more than 5 percent.

Jul 11, 2008

Metformin, combined with dietary changes and exercise, seems to help obese pre-diabetic adolescents, especially girls, lose weight, says a report in the June 2008 Journal of Pediatrics.

Researchers studied 85 obese teens with insulin resistance, 71 of whom were girls, and had them follow a goal-setting program of smaller food portions and increased exercise. The study divided the teens into two groups, one of which received metformin while the other received a placebo.

By itself, the goal-setting helped neither group achieve significant weight loss. However, 60 percent of the metformin group’s members who also cut back on their food portions experienced a decrease in their body mass index of more than 5 percent.

Metformin is a low-cost, widely available glucose control drug that is usually the first that doctors prescribe for newly diagnosed type 2 diabetics. This means it could become a powerful tool for helping adolescents lose weight and resist the onset of type 2.  

SOURCE: Journal of Pediatrics, June 2008

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Categories: Adolescent Girls, Blood Sugar, Complementary Therapies, Diabetes, Diabetes, Exercise, Food, Insulin, Kids & Teens, Losing weight, Metformin, Nutrition Advice, Research, Teenagers, Type 2 Issues, Type 2 Medications

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Posted by maxsmom77 on 12 July 2008

I have PCOS/Insulin Resistance and we had my 14 year old daughter checked. Her insulin levels were terribly high. We put her on glucophoge and low-moderate carb diet and she dropped 60lbs with little to no effort. I can't say she cut back on her food at all. Just change WHAT she ate. She STOPPED eating foods that required her insulin to work over time to process (carbs mainly). She's doing great and in great health now.

Posted by volleyball on 14 July 2008

Take a pill and you will get thin. Bad mindset to give these girls. The pills may help the obese youngster but what about a fat youngster? Where is it no longer effective? How many anorexic young women will be stealing them from the grandparents? I can see it now, Look Dear, our grandchild is visiting us AGAIN. Later, have you seen my pills.
I would like to have seen a multiple times a day BG reading and A1c results from the testing they did on these youngsters, what price thin? And where are the youngster a year later?

Posted by KidsDiabetesDr on 15 July 2008

Our practice has used metformin for years. BUT it ONLY works if teens are willing to exercise 30-60 min daily and to limit food intake with proper portions. It CAN be a springboard to success IF exercise is increased and food intake reduced.

Posted by Anonymous on 16 July 2008

i have the type 1.
can i take metformina too ???

Posted by Anonymous on 10 August 2008

You can read anywhere what to do if your BGL is too low. Eat some candy...But no where can you find out what to do if your BGL is too high other than go to the ER. Is there a quick temp' cure to high BGL?

Posted by Anonymous on 10 August 2008

Is there a quick temp cure when my BGL goes sky high. I know what to do if it bottoms quickly. Please help me. Thanks

Posted by Anonymous on 11 September 2008

I have a question for anyone with PCOS and Insulin resistance. I'm trying to find out if anyone has experienced some rate of success eating the dreamfields "low carb" pastas, they say that people with insulin resistance might not benefit from it so i'm trying to find out if insulin resistance + metformin can benefit. I'm not yet diabetic but am insulin resistant & on metformin and just looking for answers.

Posted by Anonymous on 20 May 2009

Diets and diet aids do not help anyone. The only way to successfully lose weight and get the body that you want is by using the right information. This information can be found in the book Lose Weight Using Four Easy Steps.

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