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Thirteen months ago, we published a short article about NeuropathyRx, an amalgamation of five micronutrients (including alpha lipoic acid) that is touted as a treatment for diabetic neuropathic pain. Not knowing much about it, we asked readers to comment on whether they had achieved success with this or a similar product. Here’s what they posted at diabeteshealth.com.
“Say what you want. It WORKS for me!”
“I haven't used this particular mixture of supplements, but have been using alpha lipoic acid now for over a year, and I feel it cured my "foot drop." I'm on 600mg/day of it, after going on a very high dosage for a couple of months, and the neuropathy in my feet keeps on improving all the time.”
“Metanx contains methylcobalamin (a form of vitamin B12), which is being investigated for reduction of symptoms of diabetic peripheral neuropathy. "Regular" cyanocobalamin B12 has been shown not to have this benefit. I am a physician and have seen several patients improved over the short- and long-term with oral and injectable methylcobalamin. I am aware of benefit of ALA and NAC as well.”
“My husband has been using alpha lipoic acid, 600 mg twice a day, for about eight years, and it has been very effective for his neuropathy. His uncle used it from age 82 until his death at 86, and he found it helped him to keep on gardening, which he loved. I buy a six-month supply.”
Encouraged by the enthusiasm of these readers, we asked Patty Smith Hall, the research director at Neuropathy Solutions, if more research is being done on the efficacy of NeuropathyRx. Patty wrote the following article for us.
When I was growing up in the South, my mother always told me, "You are what you eat." With Americans leading the pack in obesity and type 2 diabetes, it appears that she may have been right. Years of drive-through dinners and instant breakfasts have caught up with us, making us rethink every bite that passes our lips in our quest to fight off the complications of diabetes.
But what about the good stuff, those necessary nutrients we don't get in our daily diet? Could the lack of certain vitamins, minerals, and micronutrients be hurting us, particularly in the case of diabetic neuropathy?
That's what preliminary results from a year-long study by Dr. Mark Gostine, founder of Michigan Pain Consultants, and Dr. Larry Pawl, a recognized oncologist, appear to confirm. In a follow-up to their findings, published in the Journal of Practical Pain Management in July/August of 2007, the doctors reported that after introducing essential vitamins, minerals, and antioxidants into the diet of diabetic patients for a year, the pain, numbness, and burning associated with their diabetic neuropathy decreased by almost 65 percent.
Neuropathy is a common complication of diabetes. Peripheral nerves in the hands and feet are damaged by high blood sugar levels. Of the 20.8 million people with diabetes in the United States, an estimated 14.6 million have or will develop some form of numbness, tingling, and pain in their extremities during their lives. Although treatment for diabetic neuropathy has improved with the use of anti-epileptic drugs and antidepressants, most of the commonly used medications can cause dry mouth, constipation, blurred vision, or sedation. Because of these side effects, many (including the pharmaceutical companies) are looking to natural supplements as a way to treat diabetic neuropathy.
The purpose of Drs. Gostine and Pawl's study was to determine if long-term use of NeuropathyRx-a combination of N-acetyl cysteine, alpha lipoic acid, L-carnitine, selenium, and vitamin C-could improve the symptoms of diabetic neuropathy. Thirty-two diabetic patients with various degrees of peripheral neuropathy were followed for a period of six months to a year after introducing these micronutrients into their diet. At monthly intervals, the patients were questioned about their compliance and asked to rate their pain, numbness, and burning on a scale from zero to ten (zero being no pain and ten being the worst possible pain).
In the first open label study, spanning three months, patients reported a 41 percent drop in their numbness, a 63 percent decrease in their burning pain, and a 56 percent reduction in overall pain. In a follow-up extension study, patients who remained on the supplement continued to see improvement in their neuropathy symptoms. Nine months after starting NeuropathyRx, patients reported a decrease in their numbness by 62 percent, a drop in burning pain by 69 percent, and a reduction in overall pain by almost 65 percent.
Because these nutrients are hypothesized to work in the regeneration of the nerve sheath, Drs. Gostine and Pawl are also conducting studies with NeuropathyRx in patients with chemo-induced neuropathy and neurofibromatosis.
A non-prescriptive, NeuropathyRx costs around $40 for a one-month supply of 120 capsules and offers a money-back guarantee if the customer is not completely satisfied. NeuropathyRx is available at neuropathysolution.com or by phone at 1-877-243-6633.
Diabetes Health is the essential resource for people living with diabetes- both newly diagnosed and experienced as well as the professionals who care for them. We provide balanced expert news and information on living healthfully with diabetes. Each issue includes cutting-edge editorial coverage of new products, research, treatment options, and meaningful lifestyle issues.