Common Glucose-Control Drug May Delay or Even Prevent Onset of Type 2

Interestingly, the study was originally intended to last three years. But the results from the administration of volglibose came so quickly and dramatically after less than a year that the study was terminated.

May 1, 2009

Voglibose*, a generic drug often used in combination with sulfonylureas to control blood glucose levels, appears to delay or even prevent the onset of diabetes in people who are predisposed to the disease.

A study conducted by the Jutendo University School of medicine in Tokyo concluded that patients from impaired glucose tolerance were 40 percent less likely to develop type 2 diabetes if they regularly took volglibose three times daily.

The study tracked 1,780 Japanese patients who were considered to be at high risk of developing type 2. A little more than half the patients-897-took volglibose three times a day while the remaining 883 patients took a placebo.

While 106 of the placebo recipients went on to develop full-blown type 2, only 50 of the patients taking voglibose did so. Voglibose recipients were also 54 percent more likely than their placebo-taking counterparts to achieve normal blood sugar levels.

Interestingly, the study was originally intended to last three years. But the results from the administration of volglibose came so quickly and dramatically after less than a year that the study was terminated. 

Results of the study were recently published in the British medical journal The Lancet. 

*Voglibose is defined as an alpha-glucosidase inhibitor that is used to lower post-meal blood sugar levels in people with type 2 diabetes.

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Categories: Blood Glucose, Blood Sugar, Diabetes, Diabetes, Medications Research, Professional Issues, Type 2 Issues, Voglibose


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Comments

Posted by Anonymous on 8 May 2009

What are the side effects and adverse reactions of voglibose? Is this drug a substitute for a correct diet? Are there other non-pharmaceutical ways to achieve this goal? Does this drug allow the patient to continue a diet that encourages diabetic trend physiologically?

Posted by Anonymous on 8 May 2009

voglibose not in US Pharmacopeia.Here probably equivlent to acarbose

Posted by Anonymous on 8 May 2009

This drug impedes the absorbtion of carbohydrate and is thus equivalent to a low carbo diet without the drug.We already know that high carbo diets are the major contributors to the current diabetes epidemic.
R Bernstein MD

Posted by Anonymous on 11 May 2009

As someone who deals with diabetes daily (at work), I am so burned out on hearing that "high carbo diets are the major contributor" to DM in the U.S. Why doesn't anyone have the intestinal fortitude to say the truth--GET OFF THE COUCH and stop drinking a 6-pack of sodas a day!!! It's not just food/drink...its the lack of activity to burn off that food!

Posted by Anonymous on 1 June 2009

Does Voglibose has any side effects for kidney transplant patient?

Posted by Anonymous on 15 December 2010

It is actually a great medicine which has been approved for preventing diabetes. It is now easily available online at International Drug Mart.


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