Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • 12 Tips for Traveling With Diabetes
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter
Latest
Popular
Top Rated
Type 2 Issues Archives
Print | Email | Share | Comments (2)

Type 2 Drugs: EU Approves “Victoza,” FDA Extends Review of “Onglyza”

May 6, 2009

The FDA had originally intended to complete its review by April 30. Although a majority of the agency’s Endocrinologic and Metabolic Drugs Advisory Committee believes that saxagliptin does not present an “unacceptable” risk of creating cardiovascular problems in normal type 2 users, they want additional time to study the drug’s effects among type 2 patients who are already at a higher risk of cardiovascular problems.

The European Union's drug regulation agency has recommended that the EU approve the marketing of "Victoza" (liraglutide), a type 2 drug developed by Novo Nordisk.

The recommendation by the European Medicines Agency, based in London, could mean that the drug will reach the European market by late July.

At the same time, the U.S. Food and Drug Administration has announced that it wants 90 more days to review Onglyza (saxagliptin), a type 2 diabetes drug developed by AstraZeneca PLC and Bristol-Meyers Squibb Co.

The FDA had originally intended to complete its review by April 30. Although a majority of the agency's Endocrinologic and Metabolic Drugs Advisory Committee believes that saxagliptin does not present an "unacceptable" risk of creating cardiovascular problems in normal type 2 users, they want additional time to study the drug's effects among type 2 patients who are already at a higher risk of cardiovascular problems.

Liraglutide is in the same class as Byetta (exenatide), a long-acting glucagon-like peptide-1 analog. Like Byetta, the drug reduces blood glucose levels by increasing insulin secretion, slowing gastric emptying, and suppressing mealtime secretion of glucagon. secretion. It is intended to be taken as a once-daily drug.

Saxagliptin is a dipeptidyl peptidase-4 inhibitor, an oral glucose-lowering drug that works much the same as exenatide.  


Categories: Blood Glucose, Byetta, Diabetes, Diabetes, Food, Heart Care & Heart Disease, Insulin, Medications Research, Novo Nordisk, Onglyza, Type 2 Issues, Type 2 Medications, Victoza



You May Also Be Interested In...


Click Here To View Or Post Comments

Comments 2 comments - May 6, 2009

©1991-2014 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.