Foot Amputation Risk in Type 2s Reduced 36 Percent By Blood Fat-Lowering Drug

Fenofibrate, a drug designed to lower blood fat levels, helps reduce amputation risk.

Jun 12, 2009

Patients with type 2 diabetes reduced their risk of having a foot amputated by 36 percent when they took fenofibrate, a drug designed to lower blood fat levels.

An Australian research team at the National Health and Medical Research Council Clinical Trials Centre at the University of Sydney tracked 9,795 type 2s, ages 50 to 75, over a five-year period. Half took 200 mg of fenofibrate daily, while the other half took a placebo.

At the end of the study, the risk of a first amputation among patients taking fenofibrate was 36 percent lower than among those taking the placebo. Researchers also noted that fenofibrate takers had a 47 percent lower risk of amputations below the ankle of feet that did not have large-vessel disease.
(Large vessel disease is caused by atherosclerosis of large arteries, usually the result of cardiovascular disease, as opposed to the microvascular disease commonly found in people with type 2.)

The beneficial aspects of fenofibrate consumption seemed to emerge after 1.5 years of continuous use. However, despite the notably encouraging reduction in the risk for below-the-ankle amputations, taking fenofibrate produced no reduction in the risk for above-the-ankle amputations.

Click Here To View Or Post Comments

Categories: Amputations & Amputee, Diabetes, Diabetes, Foot Care, Health, Health Care, Medications, Medications Research, Type 2 Issues

Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter

Top Rated
Print | Email | Share | Comments (0)

You May Also Be Interested In...

Click Here To View Or Post Comments

Comments 0 comments - Jun 12, 2009

©1991-2014 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.