You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View
Latest Type 2 Issues Articles
Popular Type 2 Issues Articles
Highly Recommended Type 2 Issues Articles
Send a link to this page to your friends and colleagues.
UK-based GW Pharmaceuticals has entered into a strategic alliance with Professor Mike Cawthorne and the Clore Laboratory, University of Buckingham, to research the use of cannabinoids-chemical compounds derived from marijuana-in the treatment of type 2 diabetes.
Cawthorne has a global reputation for his research into treatments for type 2 and obesity. As Group Director for diabetes and obesity research at SmithKline Beecham, he led the research team that developed the drug Avandia (rosiglitazone), a commercially successful insulin sensitizer.
GW's research on the use of cannabinoids in the treatment of type 2 has shown beneficial effects on levels of plasma insulin and on leptin and adiponectin, hormones that factor heavily in both the onset and the treatment of the disease. The research has also shown a reduction in overall levels of cholesterol, while increasing levels of "good" HDL cholesterol.
As a result, the company has developed two cannabinoid-based drugs that have passed through Phase 1 clinical trials: delta-9-tetrahydrocannabivarin (THCV) and cannabidiol (CBD). GW reports that CBD has demonstrated potential beneficial effects on non-fatty liver disease and hypercholesterolemia, the condition in which there is an abnormal amount of cholesterol in cells and blood plasma-often a precursor to artherosclerosis.
THCV's effects so far have included raising energy expenditure, a key element in blood glucose control. GW will combine both drugs in a Phase IIa trial of their effects in the treatment of fatty liver and dyslipidemia (disruption of lipid levels in the blood) in type 2 patients.
GW says the objectives of its alliance with Cawthorne include:
Diabetes Health is the essential resource for people living with diabetes- both newly diagnosed and experienced as well as the professionals who care for them. We provide balanced expert news and information on living healthfully with diabetes. Each issue includes cutting-edge editorial coverage of new products, research, treatment options, and meaningful lifestyle issues.