Cardiologists Say Give Statins to People Even If They Don't Have Heart Disease

Cardiologists concluded from the data that statin therapy should start 10 years earlier with men than with women who have the same pre-heart disease risk factors.

Jul 15, 2009

An analysis of ten trials involving statin therapy among 70,000 participants has led an international team of cardiologists to recommend that that the cholesterol-lowering drugs be prescribed for people who do not have heart disease.

Such therapy could replace the small daily doses of prophylactic aspirin that people take to ward off arterial blockage, they say, because the benefits of statins are demonstrably higher while their drawbacks are much less.

The team's meta-analysis* showed that statin therapy reduced overall mortality by 12 percent, lowered major coronary events by 30 percent, and cut strokes by 19 percent.

The study comes in the wake of the JUPITER trial, a massive study published in 2008. JUPITER indicated that people with high levels of C-reactive protein but normal levels of cholesterol experienced 54 percent fewer heart attacks and 48 percent fewer strokes if they took statins. (C-reactive protein is a marker of inflammation, which is a major factor in diabetes and cardiovascular disease.)

Although this new study supports JUPITER's findings, the researchers undertook it before JUPITER was published because there was a lack of data on whether statins could help prevent heart disease in women and older people. Typically, preventive therapy using statins has been reserved for younger people with diabetes or high blood pressure who are at risk for cardiovascular problems.

By analyzing the data gathered from the 10 trials, the researchers found that 34 percent of the 70,000 total participants were women, and 23 percent were people with diabetes. From that enlarged set of data, the cardiologists concluded that statin therapy should start 10 years earlier with men than with women who have the same pre-heart disease risk factors.

Click Here To View Or Post Comments

Categories: Community, Diabetes, Diabetes, Health, Health Care, Heart Care & Heart Disease, Medications Research, Research, Type 2 Issues

Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • 12th Annual Product Reference Guide
  • Insulin Syringe Chart
  • Insulin Pen Needles Chart
  • Fast-Acting Glucose
  • Sharps Disposal
  • Blood Glucose Meters Chart
  • Insulin Pumps Chart
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter

Top Rated
Print | Email | Share | Comments (2)

You May Also Be Interested In...


Posted by huser on 21 July 2009

So statins reduce cardio-vascular disease? If so, why, since statins have been used have cholesterol levels gone down, but cardio-vascular disease increased? Side effects of statins are liver problems and muscle weakness (heart is a muscle). Jupiter study was ended early when they got the results they wanted and before they got the results they were afraid of.

Posted by cde on 21 July 2009

I personally think statins are probably useful, but I am reluctant to begin taking a drug that, according to the information that I have received, cannot be safely stopped. That is, once one starts on statins, he or she must continue on them until death. I am unable to verify if this is true or not. In either case, I prefer to be informed before beginning them, if that is the decision that I make.

Add your comments about this article below. You can add comments as a registered user or anonymously. If you choose to post anonymously your comments will be sent to our moderator for approval before they appear on this page. If you choose to post as a registered user your comments will appear instantly.

When voicing your views via the comment feature, please respect the Diabetes Health community by refraining from comments that could be considered offensive to other people. Diabetes Health reserves the right to remove comments when necessary to maintain the cordial voice of the diabetes community.

For your privacy and protection, we ask that you do not include personal details such as address or telephone number in any comments posted.

Don't have your Diabetes Health Username? Register now and add your comments to all our content.

Have Your Say...

Username: Password:
©1991-2015 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.